Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis

The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

1988 • 19,632 citations

Revised Criteria for the Classification of Rheumatoid Arthritis

1990 • 7,730 citations

The Future of Genetic Studies of Complex Human Diseases

1996 • 5,355 citations

The shared epitope hypothesis. an approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis

1987 • 2,539 citations

The diagnostic properties of rheumatoid arthritis antibodies recognizing a cyclic citrullinated peptide

2000 • 1,444 citations

Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies.

1998 • 1,402 citations

A Comparison of Linkage Disequilibrium Measures for Fine-Scale Mapping

1995 • 1,067 citations

Functional SNPs in the lymphotoxin-α gene that are associated with susceptibility to myocardial infarction

2002 • 942 citations

The Major Synovial Targets of the Rheumatoid Arthritis-Specific Antifilaggrin Autoantibodies Are Deiminated Forms of the α- and β-Chains of Fibrin

2001 • 629 citations

New susceptibility locus for rheumatoid arthritis suggested by a genome-wide linkage study

1998 • 480 citations

A high-throughput SNP typing system for genome-wide association studies

2001 • 434 citations

A Genomewide Screen in Multiplex Rheumatoid Arthritis Families Suggests Genetic Overlap with Other Autoimmune Diseases

2001 • 368 citations

Rheumatoid arthritis associated autoantibodies in patients with synovitis of recent onset

2000 • 360 citations

The genetics revolution and the assault on rheumatoid arthritis

1999 • 285 citations

JSNP: a database of common gene variations in the Japanese population

2002 • 278 citations

Citrullination: a small change for a protein with great consequences for rheumatoid arthritis.

2000 • 225 citations

Whole‐genome linkage analysis of rheumatoid arthritis susceptibility loci in 252 affected sibling pairs in the United Kingdom

2002 • 203 citations

Identification of the gene loci that predispose to rheumatoid arthritis.

1998 • 199 citations

THE NEUTROPHIL IN RHEUMATOID ARTHRITIS

1995 • 186 citations

Molecular Characterization of Peptidylarginine Deiminase in HL-60 Cells Induced by Retinoic Acid and 1α,25-Dihydroxyvitamin D3

1999 • 182 citations

Rheumatoid factor and antibodies to cyclic citrullinated Peptide differentiate rheumatoid arthritis from undifferentiated polyarthritis in patients with early arthritis.

2002 • 177 citations

Specific presence of intracellular citrullinated proteins in rheumatoid arthritis synovium: Relevance to antifilaggrin autoantibodies

2001 • 168 citations

Immunocytochemical localization of peptidylarginine deiminase in human eosinophils and neutrophils

2001 • 158 citations

Specific presence of intracellular citrullinated proteins in rheumatoid arthritis synovium: Relevance to antifilaggrin autoantibodies

2001 • 143 citations

Reshaping the shared epitope hypothesis: HLA‐associated risk for rheumatoid arthritis is encoded by amino acid substitutions at positions 67–74 of the HLA–DRB1 molecule

2002 • 124 citations

Insights into rheumatoid arthritis derived from the Sa immune system.

2000 • 106 citations

Major Histocompatibility Complex-Directed Susceptibility to Rheumatoid Arthritis

1998 • 105 citations

Detection of antibodies to deiminated recombinant rat filaggrin by enzyme‐linked immunosorbent assay: A highly effective test for the diagnosis of rheumatoid arthritis

2002 • 104 citations

Circumventing multiple testing: A multilocus Monte Carlo approach to testing for association

2000 • 102 citations

High diagnostic value in rheumatoid arthritis of antibodies to the stratum corneum of rat oesophagus epithelium, so-called 'antikeratin antibodies'.

1989 • 92 citations

Association of novel polymorphisms with the expression of SPARC in normal fibroblasts and with susceptibility to scleroderma

2002 • 81 citations

Immunoblotting detection of autoantibodies to human epidermis filaggrin: a new diagnostic test for rheumatoid arthritis.

1998 • 77 citations

Association of MHC and rheumatoid arthritis. HLA polymorphisms in phenotypic variants of rheumatoid arthritis.

2000 • 75 citations

Counting methods (EM algorithm) in human pedigree analysis: Linkage and segregation analysis

1977 • 63 citations

Tumor necrosis factor α 5′-flanking region, tumor necrosis factor receptor II, and HLA–DRB1 polymorphisms in Japanese patients with rheumatoid arthritis

2000 • 57 citations

Performance of two ELISAs for antifilaggrin autoantibodies, using either affinity purified or deiminated recombinant human filaggrin, in the diagnosis of rheumatoid arthritis.

2001 • 52 citations

HuD binds to three AU-rich sequences in the 3'-UTR of neuroserpin mRNA and promotes the accumulation of neuroserpin mRNA and protein

2002 • 51 citations

A Single-nucleotide Deletion Leads to Rapid Degradation ofTAP-1 mRNA in a Melanoma Cell Line

2003 • 50 citations

Autoantigenic posttranslational modifications of proteins: does it apply to rheumatoid arthritis?

2002 • 44 citations

Counting methods (EM algorithm) in human pedigree analysis: Linkage and segregation analysis

1977 • 33 citations

Immunoblotting detection of so-called 'antikeratin antibodies': a new assay for the diagnosis of rheumatoid arthritis.

1994 • 26 citations