Citrullination: a small change for a protein with great consequences for rheumatoid arthritis.

Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes.

1994 • 1,722 citations

Antinuclear Antibodies: Diagnostic Markers for Autoimmune Diseases and Probes for Cell Biology

1989 • 1,543 citations

The diagnostic properties of rheumatoid arthritis antibodies recognizing a cyclic citrullinated peptide

2000 • 1,444 citations

Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies.

1998 • 1,402 citations

The Major Synovial Targets of the Rheumatoid Arthritis-Specific Antifilaggrin Autoantibodies Are Deiminated Forms of the α- and β-Chains of Fibrin

2001 • 629 citations

The Epitopes Targeted by the Rheumatoid Arthritis-Associated Antifilaggrin Autoantibodies are Posttranslationally Generated on Various Sites of (Pro)Filaggrin by Deimination of Arginine Residues

1999 • 481 citations

New Serum Factor in Patients with Rheumatoid Arthritis: The Antiperinuclear Factor

1964 • 368 citations

Protein Unfolding by Peptidylarginine Deiminase

1996 • 340 citations

The antiperinuclear factor and the so-called antikeratin antibodies are the same rheumatoid arthritis-specific autoantibodies.

1995 • 339 citations

The mosaic of autoimmunity

1989 • 292 citations

The cytokeratin filament-aggregating protein filaggrin is the target of the so-called "antikeratin antibodies," autoantibodies specific for rheumatoid arthritis.

1993 • 259 citations

In the rheumatoid pannus, anti-filaggrin autoantibodies are produced by local plasma cells and constitute a higher proportion of IgG than in synovial fluid and serum

2000 • 226 citations

Selective Deimination of Vimentin in Calcium Ionophore-Induced Apoptosis of Mouse Peritoneal Macrophages

1998 • 209 citations

Apoptosis in rheumatoid arthritis

1999 • 197 citations

Ca2+-dependent deimination-induced disassembly of intermediate filaments involves specific modification of the amino-terminal head domain

1989 • 176 citations

Manual of Biological Markers of Disease

1996 • 166 citations

Apoptosis and inflammation

1995 • 161 citations

Death, autoantigen modifications, and tolerance.

2000 • 151 citations

Peptidylarginine Deiminase in Rat Pituitary: Sex Difference, Estrous Cycle-Related Changes, and Estrogen Dependence*

1989 • 55 citations

Deimination of 70-kD Nuclear Protein During Epidermal Apoptotic Events In Vitro

1998 • 55 citations

Expression of peptidylarginine deiminase in the uterine epithelial cells of mouse is dependent on estrogen.

1992 • 52 citations