Reshaping the shared epitope hypothesis: HLA‐associated risk for rheumatoid arthritis is encoded by amino acid substitutions at positions 67–74 of the HLA–DRB1 molecule

The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

1988 • 19,632 citations

Revised Criteria for the Classification of Rheumatoid Arthritis

1990 • 7,730 citations

The shared epitope hypothesis. an approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis

1987 • 2,539 citations

HLA-DR4 subtype frequencies in rheumatoid arthritis indicate that DRB1 is the major susceptibility locus within the HLA class II region.

1989 • 376 citations

Nomenclature for factors of the HLA system, 1991

1992 • 337 citations

Genetic basis of rheumatoid disease: HLA antigens, disease manifestations, and toxic reactions to drugs.

1978 • 335 citations

A combination of HLA-DQ beta Asp57-negative and HLA DQ alpha Arg52 confers susceptibility to insulin-dependent diabetes mellitus.

1990 • 332 citations

Homozygosity for the HLA-DRB1 allele selects for extraarticular manifestations in rheumatoid arthritis.

1992 • 229 citations

The Molecular Basis of Susceptibility to Rheumatoid Arthritis

1994 • 218 citations

Genetic typing of patients with inflammatory arthritis at presentation can be used to predict outcome

1994 • 187 citations

Could HLA-DRB1 be the protective locus in rheumatoid arthritis?

1995 • 178 citations

Association of HLA-Aw31 and HLA-DR1 with adult rheumatoid arthritis.

1982 • 168 citations

IDENTIFICATION OF HLA-Dw14 GENES IN DR4+ RHEUMATOID ARTHRITIS

1986 • 150 citations

Quantifying the exact role of HLA-DRB1 alleles in susceptibility to inflammatory polyarthritis: Results from a large, population-based study

1999 • 110 citations

Association of hla–dr4‐dw15 (drb1*0405) and dr10 with rheumatoid arthritis in a spanish population

1993 • 94 citations

The relationship between HLA-DRB1 alleles and disease subsets of rheumatoid arthritis in Japanese

1997 • 85 citations

Association of HLA alleles and clinical features in patients with synovitis of recent onset

1999 • 78 citations

HLA-DRB1 alleles encoding an aspartic acid at position 70 protect against development of rheumatoid arthritis.

2001 • 77 citations

Influence of shared epitope-negative HLA-DRB1 alleles on genetic susceptibility to rheumatoid arthritis

2001 • 74 citations

HLA‐DRwlO confers the highest susceptibility to rheumatoid arthritis in a Spanish population

1990 • 69 citations

HLA-DRB1 alleles associated with susceptibility or resistance to rheumatoid arthritis, articular deformities, and disability in Mexican Americans

1999 • 67 citations

Rheumatoid arthritis may be primarily associated with HLA‐DR4 molecules sharing a particular sequence at residues 67–74

1990 • 59 citations

Molecular analysis of HLA class II polymorphisms among different ethnic groups in Israel

1999 • 51 citations

A variant of HLA–DR4 determines susceptibility to rheumatoid arthritis in a subset of Israeli Jews

1991 • 49 citations

Clinical expression of rheumatoid arthritis in Chilean patients

1995 • 41 citations

HLA Dr Antigens in Rheumatoid Arthritis

1983 • 40 citations

No support for HLA-DQ encoded susceptibility in rheumatoid arthritis

1999 • 37 citations

Novel genetic markers of rheumatoid arthritis in chilean patients, by dr serotyping and restriction fragment length polymorphism analysis

1992 • 33 citations

Association between HLA-DR antigens and rheumatoid arthritis in Arabs.

1990 • 32 citations

The Homozygote of HLA-DRB1*0901, not its Heterozygote, is Associated with Rheumatoid Arthritis in Japanese: SHORT REPORT

1998 • 32 citations

Linkage Between Rheumatoid Arthritis Susceptibility and the Presence of HLA—DR4 and DRβ Allelic ThIrd Hypervariable Region Sequences in Southern Chinese Persons

1992 • 31 citations

HLA-DRB1*04 subtypes are associated with increased inflammatory activity in early rheumatoid arthritis

1997 • 28 citations

Prevalence of human leukocyte antigen DQA1 and DQB1 alleles in Kuwaiti Arab children with type 1 diabetes mellitus

1999 • 28 citations

Analysis of the HLA-DR gene frequencies in Japanese cases of juveniles rheumatoid arthritis and rheumatoid arthritis by oligonucleotide DNA typing

1993 • 27 citations

HLA-DR1 and DRw6 association in DR4-negative rheumatoid arthritis patients

1990 • 26 citations

THE ASSOCIATION OF HLA DR B ALLELES WITH SELF-LIMITING AND PERSISTENT FORMS OF EARLY SYMMETRICAL POLYARTHRITIS

1993 • 24 citations

HLA‐DR antigens in rheumatoid arthritis in North India

1982 • 21 citations

Histocompatibility antigens (A, B, C, and DR) in Arabs with rheumatoid arthritis.

1990 • 9 citations

Reply

2000 • 1 citations

Deleted Work

1955 • 0 citations