A Single-nucleotide Deletion Leads to Rapid Degradation ofTAP-1 mRNA in a Melanoma Cell Line

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

1984 • 3,150 citations

Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients

1999 • 1,131 citations

Implications for immunosurveillance of altered HLA class I phenotypes in human tumours

1997 • 769 citations

Human Upf Proteins Target an mRNA for Nonsense-Mediated Decay When Bound Downstream of a Termination Codon

2000 • 571 citations

A stem-loop in the 3′ untranslated region mediates iron-dependent regulation of transferrin receptor mRNA stability in the cytoplasm

1988 • 565 citations

Ex Vivo Staining of Metastatic Lymph Nodes by Class I Major Histocompatibility Complex Tetramers Reveals High Numbers of Antigen-experienced Tumor-specific Cytolytic T Lymphocytes

1998 • 534 citations

A specific mRNA binding factor regulates the iron-dependent stability of cytoplasmic transferrin receptor mRNA

1989 • 511 citations

A mechanism for exon skipping caused by nonsense or missense mutations in BRCA1 and other genes

2001 • 480 citations

Restored expression of major histocompatibility class I molecules by gene transfer of a putative peptide transporter

1991 • 413 citations

Binary specification of nonsense codons by splicing and cytoplasmic translation

1998 • 396 citations

Communication of the Position of Exon-Exon Junctions to the mRNA Surveillance Machinery by the Protein RNPS1

2001 • 376 citations

Molecular mechanism and species specificity of TAP inhibition by herpes simplex virus ICP47.

1996 • 350 citations

Role of the Nonsense-Mediated Decay Factor hUpf3 in the Splicing-Dependent Exon-Exon Junction Complex

2001 • 292 citations

At Least One Intron Is Required for the Nonsense-Mediated Decay of Triosephosphate Isomerase mRNA: a Possible Link between Nuclear Splicing and Cytoplasmic Translation

1998 • 286 citations

Exonic Splicing Enhancer Motif Recognized by Human SC35 under Splicing Conditions

2000 • 243 citations

Coordinate regulation of the human TAP1 and LMP2 genes from a shared bidirectional promoter.

1995 • 241 citations

A functionally defective allele of TAP1 results in loss of MHC class I antigen presentation in a human lung cancer

1996 • 196 citations

Immune escape of melanoma: first evidence of structural alterations in two distinct components of the MHC class I antigen processing pathway.

2001 • 189 citations

Low HLA-C expression at cell surfaces correlates with increased turnover of heavy chain mRNA.

1995 • 171 citations

Proto-oncogene PML controls genes devoted to MHC class I antigen presentation

1998 • 165 citations

LMP-associated proteolytic activities and TAP-dependent peptide transport for class 1 MHC molecules are suppressed in cell lines transformed by the highly oncogenic adenovirus 12.

1996 • 99 citations

Low cytoplasmic mRNA levels of immunoglobulin kappa light chain genes containing nonsense codons correlate with inefficient splicing.

1994 • 97 citations

Down-regulation of the expression and function of the transporter associated with antigen processing in murine tumor cell lines expressing IL-10.

1997 • 92 citations

Down-regulation of the MHC class I antigen-processing machinery after oncogenic transformation of murine fibroblasts

1998 • 90 citations

Loss of interferon-gamma inducibility of TAP1 and LMP2 in a renal cell carcinoma cell line.

2000 • 89 citations

Nonsense-Mediated Decay of HumanHEXA mRNA

2001 • 83 citations

The human intronless melanocortin 4-receptor gene is NMD insensitive

2002 • 78 citations

Two mechanisms for tumor evasion of preexisting cytotoxic T-cell responses: lessons from recurrent tumors.

1999 • 76 citations

Downregulation of peptide transporter genes in cell lines transformed with the highly oncogenic adenovirus 12.

1994 • 75 citations

Induction of immunogenicity of a human renal-cell carcinoma cell line byTAP1-gene transfer

1999 • 43 citations

Development and characterization of rabbit antisera to human MHC‐linked transporters associated with antigen processing

1996 • 24 citations

Transfection of TAP 1 gene restores HLA class I expression in human small-cell lung carcinoma

1998 • 21 citations

Regulation of the Stability of Heat-Stable Antigen mRNA by Interplay between Two Novel cis Elements in the 3′ Untranslated Region

1998 • 21 citations

Transcriptional regulation of class-I major histocompatibility complex genes transformed in murine cells is mediated by positive and negative regulatory elements

1994 • 13 citations