The inhibitory cytokine IL-35 contributes to regulatory T-cell function

Control of Regulatory T Cell Development by the Transcription Factor Foxp3

2003 • 7,902 citations

CD4+CD25+ Immunoregulatory T Cells Suppress Polyclonal T Cell Activation In Vitro by Inhibiting Interleukin 2 Production

1998 • 2,658 citations

Regulatory T Cell Lineage Specification by the Forkhead Transcription Factor Foxp3

2005 • 2,256 citations

Divergent Pro- and Antiinflammatory Roles for IL-23 and IL-12 in Joint Autoimmune Inflammation

2003 • 1,652 citations

An Essential Role for Interleukin 10 in the Function of Regulatory T Cells That Inhibit Intestinal Inflammation

1999 • 1,607 citations

Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state.

1998 • 1,579 citations

Immunologic tolerance maintained by CD25⁺ CD4⁺ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance

2001 • 1,515 citations

IL-27, a Heterodimeric Cytokine Composed of EBI3 and p28 Protein, Induces Proliferation of Naive CD4+ T Cells

2002 • 1,401 citations

Role of LAG-3 in Regulatory T Cells

2004 • 1,198 citations

Foxp3-dependent programme of regulatory T-cell differentiation

2007 • 1,106 citations

Cutting Edge: Cure of Colitis by CD4+CD25+ Regulatory T Cells

2003 • 933 citations

The lifestyle of naturally occurring CD4⁺CD25⁺Foxp3⁺ regulatory T cells

2006 • 589 citations

IL-23 plays a key role inHelicobacter hepaticus–induced T cell–dependent colitis

2006 • 570 citations

Genetically resistant mice lacking interleukin‐12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response

1996 • 483 citations

Regulatory T cells suppress systemic and mucosal immune activation to control intestinal inflammation

2006 • 463 citations

IL-12p35-Deficient Mice Are Susceptible to Experimental Autoimmune Encephalomyelitis: Evidence for Redundancy in the IL-12 System in the Induction of Central Nervous System Autoimmune Demyelination

2002 • 395 citations

A novel interleukin-12 p40-related protein induced by latent Epstein-Barr virus infection in B lymphocytes

1996 • 327 citations

Both IL-12p70 and IL-23 are synthesized during active Crohnʼs disease and are down-regulated by treatment with anti-IL-12 p40 monoclonal antibody

2005 • 319 citations

Epstein–Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietin

1997 • 308 citations

Negative Regulation of T Cell Homeostasis by Lymphocyte Activation Gene-3 (CD223)

2005 • 306 citations

Regulatory T cells and intestinal homeostasis

2005 • 279 citations

Novel IL-12 family members shed light on the orchestration of Th1 responses

2003 • 274 citations

Development of 2A peptide-based strategies in the design of multicistronic vectors

2005 • 272 citations

Generation of T-cell receptor retrogenic mice

2006 • 259 citations

Regulatory T cells in virus infections

2006 • 254 citations

Metalloproteases regulate T-cell proliferation and effector function via LAG-3

2007 • 242 citations

Potent Antitumor Activity of Interleukin-27

2004 • 240 citations

Retroviral-Mediated Transfer of the Green Fluorescent Protein Gene Into Murine Hematopoietic Cells Facilitates Scoring and Selection of Transduced Progenitors In Vitro and Identification of Genetically Modified Cells In Vivo

1997 • 230 citations

Disruption of T helper 2-immune responses in Epstein–Barr virus-induced gene 3-deficient mice

2002 • 176 citations

Rapid analysis of T-cell selection in vivo using T cell–receptor retrogenic mice

2006 • 159 citations

Natural regulatory T cells and parasites: a common quest for host homeostasis

2006 • 138 citations

Biochemical Analysis of the Regulatory T Cell Protein Lymphocyte Activation Gene-3 (LAG-3; CD223)

2004 • 122 citations

Making regulatory T cells with defined antigen specificity: role in autoimmunity and cancer

2006 • 95 citations

An Improved Method for Generating Retroviral Producer Clones for Vectors Lacking a Selectable Marker Gene

1998 • 84 citations

On the ontogeny and physiology of regulatory T cells

2001 • 82 citations

T regulatory cells and the control of allergic disease

2006 • 75 citations

Regulatory function ofin vivoanergized CD4⁺T cells

2001 • 63 citations

Profound Enhancement of T Cell Activation Mediated by the Interaction Between the TCR and the D3 Domain of CD4

1999 • 51 citations

Impaired Th1 responses in mice deficient in Epstein‐Barr virus‐induced gene 3 and challenged with physiological doses of Leishmania major

2005 • 47 citations

Autocrine secretion and the physiological concentration of cytokines

1996 • 42 citations