Enzyme-linked immunospot, cytokine flow cytometry, and tetramers in the detection of T-cell responses to a dendritic cell-based multipeptide vaccine in patients with melanoma.
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References (37)
Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.
1994 • 5,204 citations
Phenotypic Analysis of Antigen-Specific T Lymphocytes
1996 • 3,611 citations
Progress in human tumour immunology and immunotherapy
2001 • 1,327 citations
Manual of Clinical Laboratory Immunology
1992 • 1,243 citations
Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients
1999 • 1,131 citations
A solid-phase enzyme-linked immunospot (ELISPOT) assay for enumeration of specific antibody-secreting cells
1983 • 1,054 citations
Immune and clinical responses in patients with metastatic melanoma to CD34(+) progenitor-derived dendritic cell vaccine.
2001 • 828 citations
HIV-1-specific CD4+ T cells are detectable in most individuals with active HIV-1 infection, but decline with prolonged viral suppression
1999 • 766 citations
A listing of human tumor antigens recognized by T cells
2001 • 708 citations
Restoration of cytomegalovirus-specific CD4+ T-lymphocyte responses after ganciclovir and highly active antiretroviral therapy in individuals infected with HIV-1
1998 • 400 citations
Cancer Immunotherapy With Peptide-Based Vaccines: What Have We Achieved? Where Are We Going?
2002 • 400 citations
Spontaneous apoptosis of circulating T lymphocytes in patients with head and neck cancer and its clinical importance.
2002 • 375 citations
Immunoselection in vivo: Independent loss of MHC class I and melanocyte differentiation antigen expression in metastatic melanoma
1997 • 311 citations
Immunologic Monitoring of Cancer Vaccine Therapy: Results of a Workshop Sponsored by the Society for Biological Therapy
2002 • 303 citations
Detection of antigen-specific T cell cytokine expression in whole blood by flow cytometry
1998 • 285 citations
A monoclonal cytolytic T-lymphocyte response observed in a melanoma patient vaccinated with a tumor-specific antigenic peptide encoded by geneMAGE-3
2001 • 222 citations
Identification of functional subsets by flow cytometry: Intracellular detection of cytokine expression
1998 • 219 citations
Signaling abnormalities, apoptosis, and reduced proliferation of circulating and tumor-infiltrating lymphocytes in patients with oral carcinoma.
2002 • 214 citations
Mass spectrometric identification of a naturally processed melanoma peptide recognized by CD8+ cytotoxic T lymphocytes.
1995 • 208 citations
Human Cytotoxic T-Lymphocyte Repertoire to Influenza A Viruses
1998 • 187 citations
Human dendritic cell differentiation pathway from CD34+ hematopoietic precursor cells
1996 • 175 citations
Assays for monitoring cellular immune responses to active immunotherapy of cancer.
2001 • 167 citations
Optimization of whole blood antigen-specific cytokine assays for CD4+ T cells
2000 • 145 citations
Clinical cancer vaccine trials
2002 • 134 citations
Decreased zeta chain expression and apoptosis in CD3+ peripheral blood T lymphocytes of patients with melanoma.
2001 • 128 citations
Clonal expansion of melan a-specific cytotoxic T lymphocytes in a melanoma patient responding to continued immunization with melanoma-associated peptides
2000 • 110 citations
Evaluation of the Modified ELISPOT Assay for Gamma Interferon Production in Cancer Patients Receiving Antitumor Vaccines
2000 • 101 citations
Rapid Determination of Epstein-Barr Virus–Specific CD8+T-Cell Frequencies by Flow Cytometry
1999 • 100 citations
Expansion and functional maturation of human tumor antigen-specific CD8+ T cells after vaccination with antigenic peptide.
2001 • 88 citations
Cellular Immune Response Against Autologous Human Malignant Melanoma: Are In Vitro Studies Providing a Framework for a More Effective Immunotherapy?
1990 • 81 citations
Flow cytometric measurement of intracellular cytokines detects immune responses in MUC1 immunotherapy.
2000 • 62 citations
Competition of peptide-MHC class I tetrameric complexes with anti-CD3 provides evidence for specificity of peptide binding to the TCR complex
2000 • 52 citations
Frequency analysis of tumor-reactive cytotoxic T lymphocytes in peripheral blood of a melanoma patient vaccinated with autologous tumor cells
1994 • 38 citations
Detection of CD4 T-cell responses to a tumor vaccine by cytokine flow cytometry.
2001 • 31 citations
Application of IL-5 ELISPOT assays to quantification of antigen-specific T helper responses
2002 • 31 citations
Immunologic Monitoring of Clinical Trials in Patients with Cancer: TechnologyVersusCommon Sense
2000 • 28 citations
Recovery of ζ-chain expression and changes in spontaneous IL-10 production after PSA-based vaccines in patients with prostate cancer
2002 • 21 citations
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