Immunologic Monitoring of Clinical Trials in Patients with Cancer: TechnologyVersusCommon Sense

A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human Melanoma

1991 • 3,493 citations

Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma

1998 • 1,826 citations

Limiting dilution assays for the determination of immunocompetent cell frequencies. I. Data analysis.

1981 • 1,281 citations

Detection of intracellular cytokines by flow cytometry

1993 • 992 citations

Rapid Effector Function in CD8+ Memory T Cells

1997 • 652 citations

Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies

1995 • 473 citations

TAP off - tumors on

1997 • 215 citations

The effects of macrophage depletion on the clinical and pathologic expression of experimental allergic encephalomyelitis.

1981 • 215 citations

Detection and quantification of blood-derived CD8+ T lymphocytes secreting tumor necrosis factor α in response to HLA-A2.1-binding melanoma and viral peptide antigens

1996 • 179 citations

Natural killer cytotoxicity in the diagnosis of immune dysfunction: Criteria for a reproducible assay

1990 • 173 citations

Limiting dilution analysis of human T cells: a useful clinical tool

1990 • 166 citations

Tumor Immunology

1998 • 146 citations

The use of computer-assisted video image analysis for the quantification of CD8+ T lymphocytes producing tumor necrosis factor α spots in response to peptide antigens

1997 • 142 citations

Separation, phenotyping and limiting dilution analysis of T‐lymphocytes infiltrating human solid tumors

1986 • 136 citations

Precursor frequency analysis of human cytolytic T lymphocytes directed against autologous melanoma cells

1992 • 132 citations

Detection of intracellular expression and secretion of interferon‐γ at the single‐cell level after activation of human T cells with tetanus toxoid in vitro

1990 • 130 citations

Preferential clonogenic deficit of CD8-positive T-lymphocytes infiltrating human solid tumors.

1988 • 95 citations

Nonsecretory apoptotic killing by human NK cells.

1996 • 94 citations

Novel methods to monitor antigen-specific cytotoxic T-cell responses in cancer immunotherapy

1998 • 86 citations

Multiple specificities in the repertoire of a melanoma patient's cytolytic T lymphocytes directed against tumor antigen MAGE-1.A1.

1995 • 68 citations

Human tumor antigen-specific T lymphocytes and interleukin-2-activated natural killer cells: comparisons of antitumor effects in vitro and in vivo.

1998 • 30 citations

Current protocols in immunology, vol. 1

1992 • 24 citations

Immunomodulatory Function of Interferon-Gamma in Patients with Metastatic Melanoma: Results of a Phase II-B Trial in Subjects with Metastatic Melanoma, ECOG Study E 4987

1997 • 21 citations