IFN-γ protects short-term ovarian carcinoma cell lines from CTL lysis via a CD94/NKG2A-dependent mechanism

Real time quantitative PCR.

1996 • 6,155 citations

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

1999 • 5,659 citations

IFNγ and lymphocytes prevent primary tumour development and shape tumour immunogenicity

2001 • 2,658 citations

HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C

1998 • 2,114 citations

Demonstration of an interferon γ-dependent tumor surveillance system in immunocompetent mice

1998 • 1,400 citations

Escape of Human Solid Tumors from T–Cell Recognition: Molecular Mechanisms and Functional Significance

1999 • 1,168 citations

HLA-E is a major ligand for the natural killer inhibitory receptor CD94/NKG2A

1998 • 998 citations

A Common Inhibitory Receptor for Major Histocompatibility Complex Class I Molecules on Human Lymphoid and Myelomonocytic Cells

1997 • 933 citations

DEGRADATION OF CELL PROTEINS AND THE GENERATION OF MHC CLASS I-PRESENTED PEPTIDES

1999 • 898 citations

RECEPTORS FOR HLA CLASS-I MOLECULES IN HUMAN NATURAL KILLER CELLS

1996 • 871 citations

Characterization of an Antigen That Is Recognized on a Melanoma Showing Partial HLA Loss by CTL Expressing an NK Inhibitory Receptor

1997 • 746 citations

Recognition of Human Histocompatibility Leukocyte Antigen (HLA)-E Complexed with HLA Class I Signal Sequence–derived Peptides by CD94/NKG2 Confers Protection from Natural Killer Cell–mediated Lysis

1998 • 706 citations

Enhanced in vivo growth and resistance to rejection of tumor cells expressing dominant negative IFNγ receptors

1994 • 619 citations

Real-time quantitative RT–PCR after laser-assisted cell picking

1998 • 578 citations

HLA-E Surface Expression Depends on Binding of TAP-Dependent Peptides Derived from Certain HLA Class I Signal Sequences

1998 • 495 citations

Mouse CD94/NKG2A Is a Natural Killer Cell Receptor for the Nonclassical Major Histocompatibility Complex (MHC) Class I Molecule Qa-1b

1998 • 491 citations

The human major histocompatibility complex class Ib molecule HLA‐E binds signal sequence‐derived peptides with primary anchor residues at positions 2 and 9

1997 • 489 citations

HLA-E-bound peptides influence recognition by inhibitory and triggering CD94/NKG2 receptors: preferential response to an HLA-G-derived nonamer

1998 • 366 citations

Kinetics and peptide dependency of the binding of the inhibitory NK receptor CD94/NKG2-A and the activating receptor CD94/NKG2-C to HLA-E

1999 • 355 citations

The ILT2(LIR1) and CD94/NKG2A NK cell receptors respectively recognize HLA-G1 and HLA-E molecules co-expressed on target cells

1999 • 355 citations

The membrane-bound and soluble forms of HLA-G bind identical sets of endogenous peptides but differ with respect to TAP association

1995 • 320 citations

Regulation of KIR expression in human T cells: a safety mechanism that may impair protective T-cell responses

1998 • 245 citations

Lymphocyte apoptosis induced by Fas ligand- expressing ovarian carcinoma cells. Implications for altered expression of T cell receptor in tumor-associated lymphocytes.

1998 • 238 citations

HLA class I-specific inhibitory receptors in human T lymphocytes: Interleukin 15-induced expression of CD94/NKG2A in superantigen- or alloantigen-activated CD8⁺ T cells

1998 • 237 citations

Inhibition of antigen-induced T cell response and antibody-induced NK cell cytotoxicity by NKG2A: association of NKG2A with SHP-1 and SHP-2 protein-tyrosine phosphatases

1998 • 236 citations

Selective expression of interleukin 10, interferon gamma, and granulocyte-macrophage colony-stimulating factor in ovarian cancer biopsies.

1992 • 235 citations

CD94-NKG2A receptors regulate antiviral CD8+ T cell responses

2002 • 225 citations

Cytolytic T lymphocytes displaying natural killer (NK)-like activity: expression of NK-related functional receptors for HLA class I molecules (p58 and CD94) and inhibitory effect on the TCR-mediated target cell lysis or lymphokine production

1995 • 221 citations

In Vivo Expression of Natural Killer Cell Inhibitory Receptors by Human Melanoma–Specific Cytolytic T Lymphocytes

1999 • 202 citations

Differential Expression of Leukocyte Receptor Complex-Encoded Ig-Like Receptors Correlates with the Transition from Effector to Memory CTL

2001 • 181 citations

Transforming growth factor-β-induced expression of CD94/NKG2A inhibitory receptors in human T lymphocytes

1999 • 180 citations

Specific activation of the non‐classical class I histocompatibility HLA‐G antigen and expression of the ILT2 inhibitory receptor in human breast cancer

2001 • 179 citations

Expression and function of NK cell receptors in CD8+ T cells

2001 • 177 citations

NK cell recognition of non-classical HLA class I molecules

2000 • 170 citations

Tumor-specific up-regulation of the nonclassical class I HLA-G antigen expression in renal carcinoma.

2001 • 160 citations

Augmentation of antitumor effects by NK cell inhibitory receptor blockade in vitro and in vivo

2001 • 153 citations

Heterogeneity of HLA-G gene transcription and protein expression in malignant melanoma biopsies.

1999 • 146 citations

CD94 functions as a natural killer cell inhibitory receptor for different HLA class I alleles: identification of the inhibitory form of CD94 by the use of novel monoclonal antibodies

1996 • 133 citations

CD28-negative cytolytic effector T cells frequently express NK receptors and are present at variable proportions in circulating lymphocytes from healthy donors and melanoma patients

1999 • 124 citations

HLA-G and HLA-E: fundamental and pathophysiological aspects

2000 • 119 citations

Randomized Trial of Adjuvant Human Interferon Gamma Versus Observation in High-Risk Cutaneous Melanoma: a Southwest Oncology Group Study

1995 • 111 citations

Paired inhibitory and triggering NK cell receptors for HLA class I molecules

2000 • 103 citations

HLA class I recognition by killer cell Ig-like receptors

2000 • 97 citations

Tumor cytolysis by lymphocytes infiltrating ovarian malignant ascites.

1991 • 95 citations

Clinical and biological effects of intraperitoneal injections of recombinant interferon-gamma and recombinant interleukin 2 with or without tumor-infiltrating lymphocytes in patients with ovarian or peritoneal carcinoma.

2000 • 92 citations

Regulation of Inhibitory and Activating Killer-Cell Ig-Like Receptor Expression Occurs in T Cells After Termination of TCR Rearrangements

2001 • 83 citations

Expression of HLA G in human tumors is not a frequent event

1999 • 80 citations

Interferon-γ Induction of the Human Leukocyte Antigen-E Gene Is Mediated through Binding of a Complex Containing STAT1α to a Distinct Interferon-γ-responsive Element

1996 • 76 citations

Synergistic effect of IFN-γ and human cytomegalovirus protein UL40 in the HLA-E-dependent protection from NK cell-mediated cytotoxicity

2001 • 74 citations

Killer inhibitory receptor (CD158b) modulates the lytic activity of tumor-specific T lymphocytes infiltrating renal cell carcinomas

2000 • 70 citations

The Clonal Composition of a Peptide-Specific Oligoclonal CTL Repertoire Selected in Response to Persistent EBV Infection Is Stable Over Time

1998 • 67 citations

Regulation of obese (ob) mRNA and Plasma Leptin Levels in Rhesus Monkeys

1996 • 48 citations

Interferon is able to reduce tumor cell susceptibility to human lymphokine-activated killer (LAK) cells

1989 • 27 citations