Augmentation of antitumor effects by NK cell inhibitory receptor blockade in vitro and in vivo

Enhancement of Antitumor Immunity by CTLA-4 Blockade

1996 • 3,585 citations

Biology of Natural Killer Cells

1989 • 2,970 citations

Selective rejection of H–2-deficient lymphoma variants suggests alternative immune defence strategy

1986 • 2,102 citations

NK CELL RECEPTORS

1998 • 1,666 citations

MHC Class I Deficiency: Susceptibility to Natural Killer (NK) Cells and Impaired NK Activity

1991 • 474 citations

Loss of T-cell receptor zeta chain and p56lck in T-cells infiltrating human renal cell carcinoma.

1993 • 385 citations

Direct Assessment of MHC Class I Binding by Seven Ly49 Inhibitory NK Cell Receptors

1999 • 308 citations

Inhibition of natural killer cells by a cytomegalovirus MHC class I homologue in vivo

1997 • 305 citations

Ly-49D and Ly-49H associate with mouse DAP12 and form activating receptors.

1998 • 282 citations

Recognition of beta 2-microglobulin-negative (beta 2m-) T-cell blasts by natural killer cells from normal but not from beta 2m- mice: nonresponsiveness controlled by beta 2m- bone marrow in chimeric mice.

1991 • 269 citations

Cutting Edge: Ly-49D and Ly-49H Associate with Mouse DAP12 and Form Activating Receptors

1998 • 241 citations

The Role of Ly49A and 5E6(Ly49C) Molecules in Hybrid Resistance Mediated by Murine Natural Killer Cells Against Normal T Cell Blasts

1996 • 234 citations

DAP12-mediated Signal Transduction in Natural Killer Cells

1998 • 212 citations

Modulation of Natural Killer Cell Cytotoxicity in Human Cytomegalovirus Infection: The Role of Endogenous Class I Major Histocompatibility Complex and a Viral Class I Homolog

1998 • 194 citations

Allelic exclusion of Ly49-family genes encoding class I MHC-specific receptors on NK cells

1995 • 188 citations

Effects of TGF-β on the immune system: implications for cancer immunotherapy

1999 • 159 citations

Recruitment and Activation of Natural Killer (Nk) Cells in Vivo Determined by the Target Cell Phenotype

2000 • 146 citations

Positive Recognition of MHC Class I Molecules by the Ly49D Receptor of Murine NK Cells

1999 • 137 citations

Mouse Ly-49D Recognizes H-2Dd and Activates Natural Killer Cell Cytotoxicity

1999 • 137 citations

Divergent functions of lectin‐like receptors on NK cells

1997 • 135 citations

Tolerance and Alloreactivity of the Ly49D Subset of Murine NK Cells

1999 • 95 citations

Down-regulation of the expression and function of the transporter associated with antigen processing in murine tumor cell lines expressing IL-10.

1997 • 92 citations

Tumor escape from immune recognition: loss of HLA-A2 melanoma cell surface expression is associated with a complex rearrangement of the short arm of chromosome 6.

1996 • 90 citations

Multiple natural killer cell‐activating signals are inhibited by major histocompatibility complex class I expression in target cells

1994 • 81 citations

Down regulation of major histocompatibility complex class I expression in mammary carcinoma of HER-2/neu transgenic mice

1998 • 64 citations

NK cell receptor calibration: effects of MHC class I induction on killing by Ly49Ahigh and Ly49Alow NK cells.

1997 • 55 citations

The molecular basis of Natural Killer (NK) cell recognition and function

1996 • 44 citations

Dependency on intercellular adhesion molecule recognition and local interleukin-2 provision in generation of an in vivo CD8+ T-cell immune response to murine myeloid leukemia

1995 • 42 citations

Negative regulation of rat natural killer cell activity by major histocompatibility complex class I recognition

1996 • 38 citations

[The Fas/Fas-ligand system: implications in the antitumor immune response and in the activity of cytotoxic agents].

1998 • 15 citations