Killer inhibitory receptor (CD158b) modulates the lytic activity of tumor-specific T lymphocytes infiltrating renal cell carcinomas

HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C

1998 • 2,114 citations

Treatment of 283 Consecutive Patients With Metastatic Melanoma or Renal Cell Cancer Using High-Dose Bolus Interleukin 2

1994 • 1,070 citations

Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells

1998 • 892 citations

RECEPTORS FOR HLA CLASS-I MOLECULES IN HUMAN NATURAL KILLER CELLS

1996 • 871 citations

Characterization of an Antigen That Is Recognized on a Melanoma Showing Partial HLA Loss by CTL Expressing an NK Inhibitory Receptor

1997 • 746 citations

Recruitment of Tyrosine Phosphatase HCP by the Killer Cell Inhibitory Receptor

1996 • 625 citations

Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains

1995 • 575 citations

T-cell repertoire diversity and clonal expansions in normal and clinical samples

1995 • 562 citations

P58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities.

1993 • 537 citations

Existence of both inhibitory (p58) and activatory (p50) receptors for HLA-C molecules in human natural killer cells.

1995 • 446 citations

NKB1: a natural killer cell receptor involved in the recognition of polymorphic HLA-B molecules.

1994 • 343 citations

Autologous tumor-specific cytotoxic T lymphocytes in the infiltrate of human metastatic melanomas. Activation by interleukin 2 and autologous tumor cells, and involvement of the T cell receptor.

1988 • 324 citations

Superantigen-Dependent, Cell-Mediated Cytotoxicity Inhibited by MHC Class I Receptors on T Lymphocytes

1995 • 316 citations

An experimentally validated panel of subfamily‐specific oligonucleotide primers (V_α1‐w29/V_β1‐w24) for the study of human T cell receptor variable V gene segment usage by polymerase chain reaction

1992 • 302 citations

Human killer cell activatory receptors for MHC class I molecules are included in a multimeric complex expressed by natural killer cells.

1997 • 260 citations

A novel surface antigen expressed by a subset of human CD3- CD16+ natural killer cells. Role in cell activation and regulation of cytolytic function.

1990 • 254 citations

HLA class I-specific inhibitory receptors in human T lymphocytes: Interleukin 15-induced expression of CD94/NKG2A in superantigen- or alloantigen-activated CD8⁺ T cells

1998 • 237 citations

Cytolytic T lymphocytes displaying natural killer (NK)-like activity: expression of NK-related functional receptors for HLA class I molecules (p58 and CD94) and inhibitory effect on the TCR-mediated target cell lysis or lymphokine production

1995 • 221 citations

Involvement of HLA class I alleles in natural killer (NK) cell-specific functions: expression of HLA-Cw3 confers selective protection from lysis by alloreactive NK clones displaying a defined specificity (specificity 2).

1992 • 218 citations

Molecular characterization of human CD94: A type II membrane glycoprotein related to the C‐type lectin superfamily

1995 • 207 citations

In Vivo Expression of Natural Killer Cell Inhibitory Receptors by Human Melanoma–Specific Cytolytic T Lymphocytes

1999 • 202 citations

Transforming growth factor-β-induced expression of CD94/NKG2A inhibitory receptors in human T lymphocytes

1999 • 180 citations

A new gene coding for an antigen recognized by autologous cytolytic T lymphocytes on a human renal carcinoma

1996 • 174 citations

T-cells infiltrating renal cell carcinoma display a poor proliferative response even though they can produce interleukin 2 and express interleukin 2 receptors.

1993 • 158 citations

Killer cell inhibitory receptors for MHC class I molecules regulate lysis of melanoma cells mediated by NK cells, gamma delta T cells, and antigen-specific CTL.

1998 • 157 citations

A mutated HLA-A2 molecule recognized by autologous cytotoxic T lymphocytes on a human renal cell carcinoma.

1996 • 142 citations

T cell clones expressing the natural killer cell‐related p58 receptor molecule display heterogeneity in phenotypic properties and p58 function

1994 • 140 citations

A novel functional cell surface dimer (Kp43) expressed by natural killer cells and T cell receptor-gamma/delta+ T lymphocytes. I. Inhibition of the IL-2-dependent proliferation by anti-Kp43 monoclonal antibody.

1990 • 136 citations

Divergent functions of lectin‐like receptors on NK cells

1997 • 135 citations

A novel surface molecule homologous to the p58/p50 family of receptors is selectively expressed on a subset of human natural killer cells and induces both triggering of cell functions and proliferation

1996 • 130 citations

CD28-negative cytolytic effector T cells frequently express NK receptors and are present at variable proportions in circulating lymphocytes from healthy donors and melanoma patients

1999 • 124 citations

Kinetics of Interaction of HLA-C Ligands with Natural Killer Cell Inhibitory Receptors

1998 • 121 citations

Killer Cell Inhibitory Receptors for MHC Class I Molecules Regulate Lysis of Melanoma Cells Mediated by NK cells, γδ T Cells, and Antigen-Specific CTL

1998 • 121 citations

Differential Roles of N- and C-Terminal Immunoreceptor Tyrosine-Based Inhibition Motifs During Inhibition of Cell Activation by Killer Cell Inhibitory Receptors

1999 • 112 citations

Regulation of T cell lymphokine production by killer cell inhibitory receptor recognition of self HLA class I alleles.

1996 • 109 citations

A Non-AUG-Defined Alternative Open Reading Frame of the Intestinal Carboxyl Esterase mRNA Generates an Epitope Recognized by Renal Cell Carcinoma-Reactive Tumor-Infiltrating Lymphocytes In Situ

1999 • 105 citations

A hsp70-2 Mutation Recognized by CTL on a Human Renal Cell Carcinoma

1999 • 98 citations

Reduced membrane major histocompatibility complex class I density and stability in a subset of human renal cell carcinomas with low TAP and LMP expression.

1996 • 92 citations

HLA‐G recognition by human natural killer cells. Involvement of CD94 both as inhibitory and as activating receptor complex

1997 • 90 citations

The susceptibility to natural killer cell-mediated lysis of HLA class I-positive melanomas reflects the expression of insufficient amounts of different HLA class I alleles

1998 • 67 citations

Analysis of T-cell immune response in renal cell carcinoma: Polarization to type 1-like differentiation pattern, clonal T-cell expansion and tumor-specific cytotoxicity

1997 • 62 citations

In vivo local expansion of clonal T cell subpopulations in renal cell carcinoma.

1995 • 53 citations

In situ demonstration of renal-cell-carcinoma-specific T-cell clones

1996 • 51 citations

Selective loss of human leukocyte antigen class I allele expression in advanced renal cell carcinoma.

1996 • 45 citations

TCR analysis reveals significant repertoire selection during in vitro lymphocyte culture

1997 • 44 citations

Phase II Trial of Interleukin-2 and Interferon-ce in Patients with Renal Cell Carcinoma: Clinical Results and Immunologic Correlates of Response

1997 • 35 citations

Effect of tumor growth factor-beta on NK receptor expression by allostimulated CD8+ T lymphocytes.

1999 • 18 citations