Specific activation of the non‐classical class I histocompatibility HLA‐G antigen and expression of the ILT2 inhibitory receptor in human breast cancer

HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C

1998 • 2,114 citations

Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma.

1996 • 1,206 citations

Escape of Human Solid Tumors from T–Cell Recognition: Molecular Mechanisms and Functional Significance

1999 • 1,168 citations

The origin and function of tumor-associated macrophages

1992 • 1,081 citations

A Common Inhibitory Receptor for Major Histocompatibility Complex Class I Molecules on Human Lymphoid and Myelomonocytic Cells

1997 • 933 citations

Characterization of an Antigen That Is Recognized on a Melanoma Showing Partial HLA Loss by CTL Expressing an NK Inhibitory Receptor

1997 • 746 citations

Tumor antigens recognized by T cells

1997 • 552 citations

Cutting Edge: Soluble HLA-G1 Triggers CD95/CD95 Ligand-Mediated Apoptosis in Activated CD8+ Cells by Interacting with CD8

2000 • 465 citations

HLA-G expression in melanoma: A way for tumor cells to escape from immunosurveillance

1998 • 430 citations

IL-10 selectively induces HLA-G expression in human trophoblasts and monocytes

1999 • 409 citations

Thrombin receptor overexpression in malignant and physiological invasion processes

1998 • 408 citations

Concurrent and independent genetic alterations in the stromal and epithelial cells of mammary carcinoma: implications for tumorigenesis.

2000 • 400 citations

HLA-E-bound peptides influence recognition by inhibitory and triggering CD94/NKG2 receptors: preferential response to an HLA-G-derived nonamer

1998 • 366 citations

HLA-G-mediated inhibition of antigen-specific cytotoxic T lymphocytes

1999 • 313 citations

Fas ligand is positioned in mouse uterus and placenta to prevent trafficking of activated leukocytes between the mother and the conceptus.

1997 • 291 citations

Tetrameric Complexes of Human Histocompatibility Leukocyte Antigen (HLA)-G Bind to Peripheral Blood Myelomonocytic Cells

1999 • 252 citations

Regulation of KIR expression in human T cells: a safety mechanism that may impair protective T-cell responses

1998 • 245 citations

HLA-G suppresses proliferation of CD4+ T-lymphocytes

2000 • 244 citations

Inhibition of antigen-induced T cell response and antibody-induced NK cell cytotoxicity by NKG2A: association of NKG2A with SHP-1 and SHP-2 protein-tyrosine phosphatases

1998 • 236 citations

Expression of HLA-G in human mononuclear phagocytes and selective induction by IFN-gamma.

1996 • 234 citations

In Vivo Expression of Natural Killer Cell Inhibitory Receptors by Human Melanoma–Specific Cytolytic T Lymphocytes

1999 • 202 citations

TRAIL (Apo-2L) and TRAIL Receptors in Human Placentas: Implications for Immune Privilege

1999 • 191 citations

Study of tumor infiltrating lymphocytes and transforming growth factor-β as prognostic factors in breast carcinoma

1997 • 182 citations

HLA-G inhibits the allogeneic proliferative response

1999 • 177 citations

HLA class I antigen and transporter associated with antigen processing (TAP1 and TAP2) down-regulation in high-grade primary breast carcinoma lesions.

1998 • 175 citations

NK cell recognition of non-classical HLA class I molecules

2000 • 170 citations

Modulation of HLA-G Antigens Expression by Human Cytomegalovirus: Specific Induction in Activated Macrophages Harboring Human Cytomegalovirus Infection

2000 • 161 citations

Endothelial cells in chorionic fetal vessels of first trimester placenta express HLA‐G

1997 • 161 citations

Where have all the T cells gone? Mechanisms of immune evasion by tumors

1999 • 153 citations

Heterogeneity of HLA-G gene transcription and protein expression in malignant melanoma biopsies.

1999 • 146 citations

The CD85/LIR-1/ILT2 Inhibitory Receptor Is Expressed by All Human T Lymphocytes and Down-Regulates Their Functions

2000 • 142 citations

Classical and Nonclassical Class I Major Histocompatibility Complex Molecules Exhibit Subtle Conformational Differences That Affect Binding to CD8αα

2000 • 136 citations

Cell-cell adhesion mediated by CD8 and human histocompatibility leukocyte antigen G, a nonclassical major histocompatibility complex class 1 molecule on cytotrophoblasts.

1991 • 128 citations

HLA-G and HLA-E: fundamental and pathophysiological aspects

2000 • 119 citations

HLA-G, -E, -F preworkshop: tools and protocols for analysis of non-classical class I genes transcription and protein expression

2000 • 119 citations

A Specific Interferon (IFN)-stimulated Response Element of the Distal HLA-G Promoter Binds IFN-regulatory Factor 1 and Mediates Enhancement of This Nonclassical Class I Gene by IFN-β

2001 • 111 citations

HLA-G inhibits the transendothelial migration of human NK cells

2000 • 95 citations

Presence of HLA‐G‐Expressing Cells Modulates the Ability of Peripheral Blood Mononuclear Cells to Release Cytokines

1997 • 91 citations

Heat shock and arsenite induce expression of the nonclassical class I histocompatibility HLA-G gene in tumor cell lines

2000 • 90 citations

Malignant transformation of nontrophoblastic cells is associated with the expression of chorionic gonadotropin beta genes normally transcribed in trophoblastic cells.

1997 • 85 citations

Modulation of HLA-G expression in human thymic and amniotic epithelial cells

2000 • 84 citations

The immunotolerance role of HLA-G

1999 • 84 citations

The complement regulatory proteins CD46 and CD59, but not CD55, are highly expressed by glandular epithelium of human breast and colorectal tumour tissues

1998 • 84 citations

Increased expression of human histocompatibility leukocyte antigen-G in colorectal cancer cells.

1998 • 81 citations

Expression of HLA G in human tumors is not a frequent event

1999 • 80 citations

Glucocorticoid hormones upregulate levels of HLA-G transcripts in trophoblasts

2001 • 76 citations

HLA-G class I gene expression in normal and malignant hematopoietic cells

1998 • 74 citations

HLA-G expression in human melanoma cells: protection from NK cytolysis

1999 • 61 citations

HLA‐G protein expression is not induced during malignant transformation

1999 • 59 citations

Melanomas and melanoma cell lines do not express HLA‐G, and the expression cannot be induced by γIFN treatment

2000 • 51 citations

HLA‐G Expression by Tumors

2001 • 48 citations

Expression of CD94/NKG2 Subtypes on Tumor-Infiltrating Lymphocytes in Primary and Metastatic Melanoma

2000 • 34 citations

Human breast carcinoma patients develop clonable oncofetal antigen-specific effector and regulatory T lymphocytes.

1999 • 34 citations

Expression and regulation of HLA-G in human glioma cell lines

1999 • 29 citations

Human Breast Carcinoma Patients Develop Clonable Oncofetal Antigen-Specific Effector and Regulatory T Lymphocytes

1999 • 24 citations

Biological therapies for breast carcinoma: concepts for improvement in survival.

1999 • 17 citations

Analysis of HLA-G expression in tumor cell lines

1999 • 12 citations