Transcriptional regulation of the MHC II gene DRA in untransformed human thyrocytes

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins

1994 • 5,932 citations

Phosphorylated CREB binds specifically to the nuclear protein CBP

1993 • 2,039 citations

Targeted Disruption of the Stat1 Gene in Mice Reveals Unexpected Physiologic Specificity in the JAK–STAT Signaling Pathway

1996 • 1,648 citations

MHC-dependent antigen processing and peptide presentation: Providing ligands for T lymphocyte activation

1994 • 1,448 citations

ROLE OF ABERRANT HLA-DR EXPRESSION AND ANTIGEN PRESENTATION IN INDUCTION OF ENDOCRINE AUTOIMMUNITY

1983 • 1,275 citations

Continuous culture of human lymphoblasts from peripheral blood of a child with acute leukemia

1965 • 1,213 citations

Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)

1993 • 828 citations

Activation of Transcription by IFN-γ: Tyrosine Phosphorylation of a 91-kD DNA Binding Protein

1992 • 772 citations

Role of MHC Gene Products in Immune Regulation

1981 • 705 citations

Sequences and Factors: A Guide to MHC Class-II Transcription

1992 • 540 citations

Poly (ADP-ribose) polymerase, nitric oxide and cell death

1999 • 518 citations

REGULATION OF MHC CLASS II GENES: Lessons from a Disease

1996 • 488 citations

Regulation of Major Histocompatibility Complex Class-II Genes: X, Y and Other Letters of the Alphabet

1990 • 470 citations

Interferon-gamma induces HLA-DR expression by thyroid epithelium.

1985 • 314 citations

STAT-related transcription factors are constitutively activated in peripheral blood cells from acute leukemia patients

1996 • 312 citations

A New Member of the Leucine Zipper Class of Proteins that Binds to the HLA DRα Promoter

1990 • 286 citations

Congenital immunodeficiency with a regulatory defect in MHC class II gene expression lacks a specific HLA-DR promoter binding protein, RF-X

1988 • 275 citations

A gene encoding a novel RFX-associated transactivator is mutated in the majority of MHC class II deficiency patients

1998 • 272 citations

Co-evolution from yeast to mouse: cDNA cloning of the two NF-Y (CP-1/CBF) subunits.

1990 • 264 citations

Lectin-induced expression of DR antigen on human cultured follicular thyroid cells

1983 • 233 citations

Induction of Graves-like disease in mice by immunization with fibroblasts transfected with the thyrotropin receptor and a class II molecule.

1996 • 226 citations

Regulation of MHC gene expression

1993 • 215 citations

Regulation of transcription of MHC class II genes

1997 • 199 citations

Adaptor-mediated Recruitment of RNA Polymerase II to a Signal-dependent Activator

1996 • 199 citations

Monoclonal antibodies to NF-Y define its function in MHC class II and albumin gene transcription.

1992 • 192 citations

Poly(ADP-Ribose) Polymerase Binds with Transcription Enhancer Factor 1 to MCAT1 Elements To Regulate Muscle-Specific Transcription

1999 • 186 citations

CREB Regulates MHC Class II Expression in a CIITA-Dependent Manner

1999 • 183 citations

Activation of class II MHC genes requires both the X ☐ region and the class II transactivator (CIITA)

1995 • 180 citations

RFX-B Is the Gene Responsible for the Most Common Cause of the Bare Lymphocyte Syndrome, an MHC Class II Immunodeficiency

1999 • 162 citations

Poly(ADP-ribose) polymerase enhances activator-dependent transcription in vitro

1997 • 153 citations

The Transcriptional Regulatory Protein, YB-1, Promotes Single-stranded Regions in the DRA Promoter

1995 • 134 citations

PolyADP-ribose polymerase is a coactivator for AP-2-mediated transcriptional activation

1999 • 130 citations

Stat1 alpha expression is involved in IFN-gamma induction of the class II transactivator and class II MHC genes.

1996 • 125 citations

Human X-box-binding protein 1 is required for the transcription of a subset of human class II major histocompatibility genes and forms a heterodimer with c-fos.

1991 • 125 citations

Quantitative control of MHC class II expression by the transactivator CIITA

1998 • 117 citations

PARP alleles within the linked chromosomal region are associated with systemic lupus erythematosus

1999 • 110 citations

A cDNA for a human cyclic AMP response element-binding protein which is distinct from CREB and expressed preferentially in brain.

1990 • 98 citations

Long-term culture and functional characterization of follicular cells from adult normal human thyroids.

1994 • 91 citations

YB-1 DNA-binding protein represses interferon gamma activation of class II major histocompatibility complex genes.

1994 • 86 citations

Purified X2 binding protein (X2BP) cooperatively binds the class II MHC X box region in the presence of purified RFX, the X box factor deficient in the bare lymphocyte syndrome.

1995 • 86 citations

Formation of a regulatory factor X/X2 box-binding protein/nuclear factor-Y multiprotein complex on the conserved regulatory regions of HLA class II genes.

1997 • 83 citations

Affinity-purified CCAAT-box-binding protein (YEBP) functionally regulates expression of a human class II major histocompatibility complex gene and the herpes simplex virus thymidine kinase gene.

1991 • 73 citations

Differences in DNA sequence specificity among MHC class II X box binding proteins.

1989 • 73 citations

NF-X2 that binds to the DRA X2-box is activator protein 1. Expression cloning of c-Jun.

1990 • 57 citations

Transcription of a subset of human class II major histocompatibility complex genes is regulated by a nucleoprotein complex that contains c-fos or an antigenically related protein.

1991 • 52 citations

Usage of primary cells to delineate IFN-gamma-responsive DNA elements in the HLA-DRA promoter and to identify a novel IFN-gamma-enhanced nuclear factor.

1992 • 38 citations

Regulation of Major Histocompatibility Class II Gene Expression in FRTL-5 Thyrocytes: Opposite Effects of Interferon and Methimazole*

1998 • 37 citations

Hyperinducibility of HLA class II expression of thyroid follicular cells from Graves' disease. A primary defect?

1995 • 33 citations

Major Histocompatibility Class II HLA-DRα Gene Expression in Thyrocytes: Counter Regulation by the Class II Transactivator and the Thyroid Y Box Protein

1998 • 30 citations

HLA-DMB expression by thyrocytes: indication of the antigen-processing and possible presenting capability of thyroid cells

1999 • 26 citations

Induction of CIITA and modification of in vivo HLA-DR promoter occupancy in normal thymic epithelial cells treated with IFN-gamma: similarities and distinctions with respect to HLA-DR-constitutive B cells.

1996 • 26 citations

Demonstration of cross-reactivity between bacterial antigens and class I human leukocyte antigens by using monoclonal antibodies to Shigella flexneri

1990 • 17 citations

An ATF/CREB binding motif is required for aberrant constitutive expression of the MHC class II DRα promoter and activation by SV4O T-antigen

1992 • 16 citations

Regulation of Major Histocompatibility (MHC) Class II Human Leukocyte Antigen-DRα Gene Expression in Thyrocytes by Single Strand Binding Protein-1, a Transcription Factor That Also Regulates Thyrotropin Receptor and MHC Class I Gene Expression

1998 • 14 citations

The DNA mobility shift assay

1999 • 11 citations

Affinity Enrichment and Functional Characterization of TRAX1, a Novel Transcription Activator and X1-Sequence-Binding Protein of HLA-DRA

1995 • 10 citations

Deleted Work

1955 • 0 citations