PARP alleles within the linked chromosomal region are associated with systemic lupus erythematosus

The 1982 revised criteria for the classification of systemic lupus erythematosus

1982 • 14,553 citations

Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM).

1993 • 3,693 citations

Genetic Dissection of Complex Traits

1994 • 3,497 citations

REGULATION OF IMMUNE RESPONSES BY TGF-β

1998 • 1,908 citations

Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies

1998 • 1,431 citations

Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells

1997 • 1,034 citations

Complete multipoint sib-pair analysis of qualitative and quantitative traits.

1995 • 929 citations

The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Belgian Diabetes Registry

1996 • 794 citations

A novel polymorphism of FcgammaRIIIa (CD16) alters receptor function and predisposes to autoimmune disease.

1997 • 698 citations

An extended transmission/disequilibrium test (TDT) for multi‐allele marker loci

1995 • 624 citations

Post-translational modification of poly(ADP-ribose) polymerase induced by DNA strand breaks

1995 • 600 citations

Assessing the role of HLA-linked and unlinked determinants of disease.

1987 • 548 citations

Polygenic control of susceptibility to murine systemic lupus erythematosus

1994 • 484 citations

Successful treatment of autoimmunity in NZB/NZW F1 mice with monoclonal antibody to L3T4.

1985 • 466 citations

Genome scan of human systemic lupus erythematosus: Evidence for linkage on chromosome 1q in African-American pedigrees

1998 • 458 citations

The epidemiology of systemic lupus erythematosus

1973 • 418 citations

A Log-Linear Approach to Case-Parent–Triad Data: Assessing Effects of Disease Genes That Act Either Directly or through Maternal Effects and That May Be Subject to Parental Imprinting

1998 • 399 citations

A genome-wide search for susceptibility genes in human systemic lupus erythematosus sib-pair families

1998 • 362 citations

Lupus susceptibility loci in New Zealand mice.

1994 • 359 citations

Synovium as a source of increased amino-terminal parathyroid hormone-related protein expression in rheumatoid arthritis. A possible role for locally produced parathyroid hormone-related protein in the pathogenesis of rheumatoid arthritis.

1998 • 340 citations

GENETIC SUSCEPTIBILITY TO SYSTEMIC LUPUS ERYTHEMATOSUS

1998 • 313 citations

HUMAN TYPE 1 DIABETES AND THE INSULIN GENE: Principles of Mapping Polygenes

1996 • 291 citations

Evidence for linkage of a candidate chromosome 1 region to human systemic lupus erythematosus.

1997 • 279 citations

Transient Poly(ADP-ribosyl)ation of Nuclear Proteins and Role of Poly(ADP-ribose) Polymerase in the Early Stages of Apoptosis

1998 • 274 citations

A connective tissue disease screening questionnaire for population studies

1995 • 216 citations

Hereditary C1q deficiency and systemic lupus erythematosus

1994 • 213 citations

Reversal of advanced murine lupus in NZB/NZW F1 mice by treatment with monoclonal antibody to L3T4.

1987 • 211 citations

DNA repair: PARP – another guardian angel?

1998 • 173 citations

Synergistic effect betweenIL-10 andbcl-2 genotypes in determining susceptibility to systemic lupus erythematosus

1998 • 159 citations

Analysis of the New Zealand Black contribution to lupus-like renal disease. Multiple genes that operate in a threshold manner.

1995 • 146 citations

Genetic susceptibility to Alzheimer disease

1995 • 128 citations

Interaction of the Transcription Factor YY1 with Human Poly(ADP-Ribosyl) Transferase

1997 • 100 citations

Apoptosis in the rheumatic diseases

1997 • 94 citations

Delayed Repair of DNA Damage by Ionizing Radiation in Cells from Patients with Juvenile Systemic Lupus Erythematosus and Rheumatoid Arthritis

1997 • 75 citations

Characterization of a putative promoter region of the human poly(ADP-ribose) polymerase gene: Structural similarity to that of the DNA polymerase β gene

1990 • 41 citations

Altered metabolism of poly(adp‐ribose) in the peripheral blood lymphocytes of patients with systemic lupus erythematosus

1989 • 28 citations

Decreased mRNA Levels Coding for Poly(ADP-Ribose) Polymerase in Lymphocytes of Patients with SLE

1994 • 19 citations

A human homeobox gene, HB24, inhibits development of CD4+ T cells and impairs thymic involution in transgenic mice.

1993 • 18 citations

Altered poly(ADP-ribose) metabolism in family members of patients with systemic lupus erythematosus.

1994 • 12 citations

DNA repair deficiency in systemic lupus erythematosus: cause or consequence of disease and implications for management

1995 • 11 citations