1,3-Di(2-[5-3H]tolyl)guanidine: a selective ligand that labels sigma-type receptors for psychotomimetic opiates and antipsychotic drugs.

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1980 • 8,534 citations

The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog.

1976 • 2,883 citations

Brain dopamine receptors.

1980 • 1,878 citations

A practical computer-based approach to the analysis of radioligand binding experiments

1983 • 834 citations

CLASSIFICATION OF OPIOID RECEPTORS

1983 • 787 citations

Light microscopic localization of brain opiate receptors: a general autoradiographic method which preserves tissue quality

1982 • 466 citations

Differentiation of delta and mu opiate receptor localizations by light microscopic autoradiography.

1980 • 463 citations

Evidence for sigma opioid receptor: binding of [3H]SKF-10047 to etorphine-inaccessible sites in guinea-pig brain.

1982 • 409 citations

Sigma opiates and certain antipsychotic drugs mutually inhibit (+)-[3H] SKF 10,047 and [3H]haloperidol binding in guinea pig brain membranes.

1984 • 348 citations

Pharmacological and autoradiographic discrimination of sigma and phencyclidine receptor binding sites in brain with (+)-[3H]SKF 10,047, (+)-[3H]-3-[3-hydroxyphenyl]-N-(1-propyl)piperidine and [3H]-1-[1-(2-thienyl)cyclohexyl]piperidine.

1986 • 339 citations

3-PPP, a new centrally acting DA-receptor agonist with selectivity for autoreceptors

1981 • 229 citations

Naloxone-inaccessible sigma receptor in rat central nervous system.

1983 • 214 citations

Central dopamine receptor agonist and antagonist actions of the enantiomers of 3-PPP

1983 • 200 citations

Psychotomimetic opiate receptors labeled and visualized with (+)-[3H]3-(3-hydroxyphenyl)-N-(1-propyl)piperidine.

1984 • 199 citations

Naltrexone fails to antagonize the σ effects of PCP and SKF 10,047 in the dog

1983 • 187 citations

Locomotor activity and antinociception after putative mu, kappa and sigma opioid receptor agonists in the rat: influence of dopaminergic agonists and antagonists.

1981 • 176 citations

Autoradiographic localization of μ- and δ-opiate receptors in the forebrain of the rat

1986 • 170 citations

(+)-[3H]SKF 10,047, (+)-[3H]ethylketocyclazocine, μ, κ, δ and phencyclidine binding sites in guinea pig brain membranes

1985 • 168 citations

Stereoisomers of N -Allylnormetazocine: Phencyclidine-Like Behavioral Effects in Squirrel Monkeys and Rats

1982 • 165 citations

Demonstration of [3H]cyclazocine binding to multiple opiate receptor sites.

1981 • 151 citations

Phencyclidine and σ opiate receptors in brain: Biochemical and autoradiographical differentiation

1985 • 124 citations

Subjective effects of narcotic antagonists cyclazocine and nalorphine on the Addiction Research Center Inventory (ARCI)

1970 • 124 citations

Kappa opiate receptors localized by autoradiography to deep layers of cerebral cortex: relation to sedative effects.

1982 • 108 citations

Characterization and autoradiographic visualization of (+)-[3H]SKF10,047 binding in rat and mouse brain: further evidence for phencyclidine/"sigma opiate" receptor commonality.

1986 • 101 citations

Dopamine receptor agonistic and antagonistic effects of 3-PPP enantiomers

1983 • 90 citations

Phencyclidine (PCP): A Review and Perspectives

1982 • 83 citations

Stereoisomers of [3H]-N-allylnormetazocine bind to different sites in mouse brain.

1984 • 71 citations

Pharmacological evaluation of N-allynormetazocine (SKF 10,047) on the basis of its discriminative stimulus properties in the rat.

1983 • 70 citations

The binding and analgesic properties of a sigma opiate, SKF 10,047.

1981 • 53 citations

Quantitative localization of [3H]TCP binding in rat brain by light microscopy autoradiography

1985 • 53 citations

Sigma receptors mediate the psychotomimetic effects of N-allylnormetazocine (SKF-10,047), but not its opioid agonistic-antagonistic properties

1984 • 48 citations

III. Simple tests that differentiate prototype agonists at opiate receptors

1981 • 36 citations

Three-choice drug discrimination: Phencyclidine-like stimulus effects of opioids

1983 • 28 citations

Demonstration of non-opioid sigma binding with (d)3H-SKF 10047 in guinea pig brain.

1985 • 6 citations