Noncompetitive excitatory amino acid receptor antagonists

Glycine potentiates the NMDA response in cultured mouse brain neurons

1987 • 3,116 citations

The Excitatory Amino Acid Receptors: Their Classes, Pharmacology, and Distinct Properties in the Function of the Central Nervous System

1989 • 2,203 citations

Ethanol Inhibits NMDA-Activated Ion Current in Hippocampal Neurons

1989 • 1,456 citations

Requirement for Glycine in Activation of NMDA-Receptors Expressed in Xenopus Oocytes

1988 • 1,415 citations

Micromolar concentrations of Zn2+ antagonize NMDA and GABA responses of hippocampal neurons

1987 • 852 citations

Cooperative Modulation of [³H]MK‐801 Binding to the N‐Methyl‐d‐Aspartate Receptor‐Ion Channel Complex by l‐Glutamate, Glycine, and Polyamines

1988 • 755 citations

Use-dependent block of excitatory amino acid currents in cultured neurons by ketamine

1987 • 380 citations

Classification and nomenclature of phencyclidine and sigma receptor sites

1987 • 272 citations

Excitatory amino acids in health and disease.

1988 • 254 citations

Phencyclidine and psychotomimetic sigma opiates: recent insights into their biochemical and physiological sites of action

1988 • 189 citations

Tricyclic antidepressants block N‐methyl‐D‐aspartate receptors: similarities to the action of zinc

1988 • 189 citations

Radioligand binding to central phencyclidine recognition sites is dependent on excitatory amino acid receptor agonists

1986 • 182 citations

Phencyclidine and related drugs bind to the activated receptor-channel complex in rat brain membranes

1987 • 170 citations

Spider toxins as tools for dissecting elements of excitatory amino acid transmission

1988 • 165 citations

Ifenprodil and SL 82.0715 are antagonists at the polyamine site of the N-methyl-D-aspartate (NMDA) receptor

1989 • 154 citations

Inhibition of Excitatory Amino Acid‐Stimulated Phosphoinositide Hydrolysis in the Neonatal Rat Hippocampus by 2‐Amino‐3‐Phosphonopropionate

1989 • 114 citations

Kinetic characterization of the phencyclidine-N-methyl-D-aspartate receptor interaction: evidence for a steric blockade of the channel

1988 • 112 citations

Antagonism of N-methyl-D-aspartate-induced transmitter release in the rat striatum by phencyclidine-like drugs and its relationship to turning behavior.

1985 • 109 citations

Behavioral and biochemical stereoselectivity of sigma opiate/PCP receptors

1984 • 104 citations

Barbiturates, alcohols and the CNS excitatory neurotransmission: Specific effects on the kainate and quisqualate receptors

1984 • 98 citations

Neocortical epileptogenesis in vitro: studies with N-methyl-D-aspartate, phencyclidine, sigma and dextromethorphan receptor ligands.

1989 • 97 citations

Antagonism of responses to excitatory amino acids on rat cortical neurones by the spider toxin, argiotoxin₆₃₆

1989 • 93 citations

The discriminative stimulus effects of N-methyl-d-aspartate antagonists in phencyclidine-trained rats

1988 • 56 citations

Phencyclidine-like behavioral effects in pigeons induced by systemic administration of the excitatory amino acid antagonist, 2-amino-5-phosphonovalerate

1986 • 54 citations

Voltage-dependent block of excitatory amino acid currents by pentobarbital

1986 • 53 citations

Effects of a spider toxin (JSTX) on hippocampal CA1 neurons in vitro

1989 • 47 citations

The competitive N-methyl-D-aspartate (NMDA) antagonist CGS 19755 attenuates the rate-decreasing effects of NMDA in rhesus monkeys without producing ketamine-like discriminative stimulus effects

1989 • 41 citations

Receptor site topographies for phencyclidine-like and sigma drugs: predictions from quantitative conformational, electrostatic potential, and radioreceptor analyses.

1988 • 36 citations

Non‐Competitive Antagonism of N‐Methyl‐D‐Aspartate by Displacement of an Endogenous Glycine‐Like Substance

1989 • 32 citations

Effects of barbiturates on responses evoked by excitatory amino acids in slices of rat olfactory cortex

1987 • 25 citations