Caloric restriction attenuates β‐amyloid neuropathology in a mouse model of Alzheimer's disease

Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice

1996 • 4,118 citations

Pathways towards and away from Alzheimer's disease

2004 • 2,936 citations

Insulin-degrading enzyme regulates the levels of insulin, amyloid β-protein, and the β-amyloid precursor protein intracellular domain in vivo

2003 • 1,393 citations

Constitutive and regulated α-secretase cleavage of Alzheimer’s amyloid precursor protein by a disintegrin metalloprotease

1999 • 1,115 citations

Alzheimer's Disease

2004 • 1,082 citations

Age-Dependent Changes in Brain, CSF, and Plasma Amyloid β Protein in the Tg2576 Transgenic Mouse Model of Alzheimer's Disease

2001 • 990 citations

Evidence That Tumor Necrosis Factor α Converting Enzyme Is Involved in Regulated α-Secretase Cleavage of the Alzheimer Amyloid Protein Precursor

1998 • 922 citations

A Low-Carbohydrate, Ketogenic Diet versus a Low-Fat Diet To Treat Obesity and Hyperlipidemia

2004 • 911 citations

An 18-Year Follow-up of Overweight and Risk of Alzheimer Disease

2003 • 793 citations

Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake

2003 • 688 citations

The effects of low-carbohydrate versus conventional weight loss diets in severely obese adults: One-year follow-up of a randomized trial

2004 • 627 citations

A disintegrin-metalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alzheimer disease mouse model

2004 • 609 citations

Diet‐induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease

2004 • 609 citations

Caloric Intake and the Risk of Alzheimer Disease

2002 • 464 citations

Modification of Brain Aging and Neurodegenerative Disorders by Genes, Diet, and Behavior

2002 • 436 citations

Association between features of the insulin resistance syndrome and alzheimer's disease independently of apolipoprotein e4 phenotype: cross sectional population based study

1997 • 427 citations

Incidence of Dementia and Alzheimer Disease in 2 Communities

2001 • 378 citations

Neurodegenerative disorders associated with diabetes mellitus

2004 • 351 citations

A Loss of Function Mutation of Presenilin-2 Interferes with Amyloid β-Peptide Production and Notch Signaling

1999 • 306 citations

The Profile of Soluble Amyloid β Protein in Cultured Cell Media

1996 • 293 citations

Amyloid-β peptide levels in brain are inversely correlated with insulysin activity levels in vivo

2003 • 285 citations

Membrane-anchored metalloprotease MDC9 has an α-secretase activity responsible for processing the amyloid precursor protein

1999 • 260 citations

Augmented Senile Plaque Load in Aged Female β-Amyloid Precursor Protein-Transgenic Mice

2001 • 260 citations

Comparison of a Low-Fat Diet to a Low-Carbohydrate Diet on Weight Loss, Body Composition, and Risk Factors for Diabetes and Cardiovascular Disease in Free-Living, Overweight Men and Women

2004 • 225 citations

Progressive development of insulin resistance phenotype in male mice with complete aromatase (CYP19) deficiency

2003 • 182 citations

Secretion of the beta/A4 amyloid precursor protein. Identification of a cleavage site in cultured mammalian cells.

1991 • 178 citations

Presenilin Redistribution Associated with Aberrant Cholesterol Transport Enhances β-Amyloid ProductionIn Vivo

2003 • 173 citations

A comparative study of histological and immunohistochemical methods for neurofibrillary tangles and senile plaques in Alzheimer's disease

1992 • 164 citations

Raft disorganization leads to reduced plasmin activity in Alzheimer's disease brains

2003 • 124 citations

Differential vulnerability of oculomotor, facial, and hypoglossal nuclei in G86R superoxide dismutase transgenic mice

2000 • 112 citations

Cardiovascular and Other Risk Factors for Alzheimer's Disease and Vascular Dementia

2000 • 111 citations

Insulin resistance contributes to aberrant stress responses in the Tg2576 mouse model of Alzheimer's disease

2004 • 108 citations

Stereologic assessment of the total cortical volume occupied by amyloid deposits and its relationship with cognitive status in aging and Alzheimer’s disease

2002 • 107 citations

The role of ADAM10 and ADAM17 in the ectodomain shedding of angiotensin converting enzyme and the amyloid precursor protein

2004 • 90 citations

Role of glucocorticoids in mediating effects of fasting and diabetes on hypothalamic gene expression.

2003 • 86 citations

Amyloid at the cutting edge: activation of α-secretase prevents amyloidogenesis in an Alzheimer disease mouse model

2004 • 85 citations

Glucose intolerance, cognitive impairment and Alzheimer’s disease

1998 • 73 citations

Anti‐amyloid activity of neprilysin in plaque‐bearing mouse models of Alzheimer's disease

2004 • 45 citations

Adrenalectomy stimulates hypothalamic proopiomelanocortin expression but does not correct diet-induced obesity.

2003 • 19 citations