Electrophysiological Characterization of the Rat Epithelial Na+ Channel (rENaC) Expressed in MDCK Cells

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Down-Regulation of Na⁺/K⁺ATPase Activity by Human Parvovirus B19 Capsid Protein VP1

2013 • 8,607 citations

Regulation of the Voltage Gated K<sup>+</sup> Channel K<sub>v1.3</sub> by Recombinant Human Klotho Protein

2014 • 5,592 citations

Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits

1994 • 1,943 citations

The Kidney: Physiology and Pathophysiology

1992 • 1,714 citations

Ionic Blockage of Sodium Channels in Nerve

1973 • 1,590 citations

Liddle's syndrome: Heritable human hypertension caused by mutations in the β subunit of the epithelial sodium channel

1994 • 1,238 citations

Epithelial sodium channels: function, structure, and regulation

1997 • 1,154 citations

CFTR as a cAMP-Dependent Regulator of Sodium Channels

1995 • 1,074 citations

Epithelial sodium channel related to proteins involved in neurodegeneration

1993 • 911 citations

Early death due to defective neonatal lung liquid clearance in αENaC-deficient mice

1996 • 873 citations

WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome.

1996 • 828 citations

Mutations in subunits of the epithelial sodium channel cause salt wasting with hyperkalaemic acidosis, pseudohypoaldosteronism type 1

1996 • 794 citations

Regulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination

1997 • 696 citations

Liquid junction potentials and small cell effects in patch-clamp analysis

1991 • 681 citations

Cell surface expression of the epithelial Na channel and a mutant causing Liddle syndrome: A quantitative approach

1996 • 418 citations

The heterotetrameric architecture of the epithelial sodium channel (ENaC)

1998 • 408 citations

[16] Electrophysiologic recordings from Xenopus oocytes

1998 • 361 citations

Expression cloning of an epithelial amiloride‐sensitive Na⁺ channel

1993 • 340 citations

Current—voltage curve of sodium channels and concentration dependence of sodium permeability in frog skin

1977 • 321 citations

Membrane topology of the epithelial sodium channel in intact cells

1994 • 311 citations

Amiloride-sensitive Na channels from the apical membrane of the rat cortical collecting tubule.

1986 • 280 citations

Identification of Amino Acid Residues in the α, β, and γ Subunits of the Epithelial Sodium Channel (ENaC) Involved in Amiloride Block and Ion Permeation

1997 • 254 citations

A novel spice–site mutation in the γ subunit of the epithelial sodium channel gene in three pseudohypoaldosteronism type 1 families

1996 • 241 citations

[19] Electrophysiological recording from Xenopus oocytes

1992 • 236 citations

Cloning and expression of the beta- and gamma-subunits of the human epithelial sodium channel

1995 • 234 citations

The lung amiloride-sensitive Na+ channel: biophysical properties, pharmacology, ontogenesis, and molecular cloning.

1994 • 229 citations

Membrane topology of the amiloride-sensitive epithelial sodium channel.

1994 • 220 citations

Biochemical analysis of the membrane topology of the amiloride-sensitive Na+ channel.

1994 • 219 citations

Cystic Fibrosis Transmembrane Conductance Regulator Inverts Protein Kinase A-mediated Regulation of Epithelial Sodium Channel Single Channel Kinetics

1997 • 200 citations

The C2 Domain of the Ubiquitin Protein Ligase Nedd4 Mediates Ca2+-dependent Plasma Membrane Localization

1997 • 199 citations

Epithelial Na Channels: Function and Diversity

1992 • 193 citations

Diversity of Channels Generated by Different Combinations of Epithelial Sodium Channel Subunits

1997 • 179 citations

Different homologous subunits of the amiloride-sensitive Na+ channel are differently regulated by aldosterone.

1994 • 166 citations

Effects of cell Ca and pH on Na channels from rat cortical collecting tubule

1987 • 161 citations

Cloning, expression, and tissue distribution of a human amiloride-sensitive Na+ channel

1994 • 158 citations

The role of sodium-channel density in the natriferic response of the toad urinary bladder to an antidiuretic hormone

1982 • 154 citations

Effects of luminal Na+ on single Na+ channels in A6 cells, a regulatory role for protein kinase C

1989 • 129 citations

Current-voltage analysis of apical sodium transport in toad urinary bladder: Effects of inhibitors of transport and metabolism

1980 • 117 citations

Gating of Na channels in the rat cortical collecting tubule: effects of voltage and membrane stretch.

1996 • 111 citations

The highly selective low-conductance epithelial Na channel of Xenopus laevis A6 kidney cells

1995 • 104 citations

Conductance and gating of epithelial Na channels from rat cortical collecting tubule. Effects of luminal Na and Li.

1988 • 104 citations

Triple-barrel Organization of ENaC, a Cloned Epithelial Na+ Channel

1996 • 100 citations

Role of actin in regulation of epithelial sodium channels by CFTR

1997 • 99 citations

Feedback regulation of Na channels in rat CCT. II. Effects of inhibition of Na entry

1993 • 93 citations

Cytosolic Na+ controls and epithelial Na+ channel via the Go guanine nucleotide-binding regulatory protein.

1996 • 87 citations

Protein kinase regulation of a cloned epithelial Na+ channel.

1996 • 81 citations

Highly inducible synthesis of heterologous proteins in epithelial cells carrying a glucocorticoid-responsive vector

1992 • 62 citations

Cloning of a bovine renal epithelial Na+ channel subunit

1995 • 58 citations

Direct inhibition of epithelial Na+ channels by a pH-dependent interaction with calcium, and by other divalent ions

1987 • 57 citations

Does calcium couple the apical and basolateral membrane permeabilities in epithelia?

1984 • 56 citations

Modulation of apical Na permeability of the toad urinary bladder by intracellular Na, Ca, and H

1985 • 51 citations

Relation between intracellular sodium and active sodium transport in rabbit colon: Current-voltage relations of the apical sodium entry mechanism in the presence of varying luminal sodium concentrations

1983 • 48 citations

Ca2+-dependent, temperature-sensitive regulation of Na+ channels in tight epithelia. A study using membrane vesicles.

1985 • 47 citations

Voltage dependence of Na channel blockage by amiloride: Relaxation effects in admittance spectra

1985 • 44 citations

A highly calcium‐selective cation current activated by intracellular calcium release in MDCK cells.

1995 • 39 citations

Ion Channels in Madin-Darby Canine Kidney Cells

1990 • 34 citations

Cytosolic Na^+ controls an epithelial Na^+ chanel via the G_o guaninine nucleotide-binding regulatory protein

1996 • 34 citations

Feedback inhibition of sodium uptake in K+-depolarized toad urinary bladders

1984 • 31 citations

Ca2+-induced down-regulation of Na+ channels in toad bladder epithelium.

1986 • 29 citations

Regulation by Na+ and Ca2+ of renal epithelial Na+ channels reconstituted into planar lipid bilayers.

1995 • 29 citations

Control of the Amiloride-Sensitive Na + Current in Salivary Duct Cells by Extracellular Sodium

1996 • 25 citations

Ca-EGTA buffer in physiological solution

1987 • 24 citations

Cloning and induction by low NaCl intake of avian intestine Na+ channel subunits

1997 • 23 citations

Relationships among sodium current, permeability, and Na activities in control and glucocorticoid-stimulated rabbit descending colon

1986 • 12 citations

Chapter 3 Feedback Regulation of Epithelial Sodium Channels

1989 • 11 citations

Guanine-Nucleotide-Binding Regulatory Proteins

1985 • 7 citations

Deleted Work

1955 • 0 citations