Serum and Glucocorticoid-regulated Kinase Modulates Nedd4-2-mediated Inhibition of the Epithelial Na+Channel

Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits

1994 • 1,943 citations

Epithelial sodium channels: function, structure, and regulation

1997 • 1,154 citations

WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome.

1996 • 828 citations

Epithelial sodium channel regulated by aldosterone-induced protein sgk

1999 • 728 citations

Aldosterone-mediated regulation of ENaC α, β, and γ subunit proteins in rat kidney

1999 • 713 citations

Interaction with the NMDA receptor locks CaMKII in an active conformation

2001 • 695 citations

Molecular Genetics of Human Blood Pressure Variation

1996 • 637 citations

Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway

1999 • 555 citations

sgk Is an Aldosterone-induced Kinase in the Renal Collecting Duct

1999 • 452 citations

Mechanism by which Liddle's syndrome mutations increase activity of a human epithelial Na+ channel

1995 • 408 citations

Identification of a PY motif in the epithelial Na channel subunits as a target sequence for mutations causing channel activation found in Liddle syndrome.

1996 • 397 citations

Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase

1999 • 396 citations

Calcium/calmodulin-dependent protein kinase II is associated with the N -methyl- <scp>d</scp> -aspartate receptor

1999 • 377 citations

Defective regulation of the epithelial Na+ channel by Nedd4 in Liddle's syndrome

1999 • 358 citations

A novel mouse Nedd4 protein suppresses the activity of the epithelial Na⁺channel

2001 • 290 citations

The Serum and Glucocorticoid Kinase sgk Increases the Abundance of Epithelial Sodium Channels in the Plasma Membrane of Xenopus Oocytes

1999 • 274 citations

Cloning and expression of the beta- and gamma-subunits of the human epithelial sodium channel

1995 • 234 citations

AKAP signaling complexes at the cytoskeleton

2001 • 223 citations

SGK integrates insulin and mineralocorticoid regulation of epithelial sodium transport

2001 • 214 citations

The C2 Domain of the Ubiquitin Protein Ligase Nedd4 Mediates Ca2+-dependent Plasma Membrane Localization

1997 • 199 citations

Inhibition of the Epithelial Na+ Channel by Interaction of Nedd4 with a PY Motif Deleted in Liddle's Syndrome

1998 • 178 citations

The Nedd4-like Protein KIAA0439 Is a Potential Regulator of the Epithelial Sodium Channel

2001 • 154 citations

Liddle’s syndrome mutations disrupt cAMP-mediated translocation of the epithelial Na+ channel to the cell surface

2000 • 148 citations

Nedd4 mediates control of an epithelial Na ⁺ channel in salivary duct cells by cytosolic Na ⁺

1998 • 140 citations

Distinct characteristics of two human Nedd4 proteins with respect to epithelial Na⁺channel regulation

2001 • 127 citations

Immunolocalization of the ubiquitin-protein ligase Nedd4 in tissues expressing the epithelial Na+ channel (ENaC)

1997 • 85 citations

Multiple WW Domains, but Not the C2 Domain, Are Required for Inhibition of the Epithelial Na+ Channel by Human Nedd4

2001 • 84 citations

A Single Point Mutation in a Group I WW Domain Shifts Its Specificity to That of Group II WW Domains

1999 • 67 citations

Human Nedd4 interacts with the human epithelial Na+ channel: WW3 but not WW1 binds to Na+-channel subunits

2000 • 54 citations

Disorders of the epithelial sodium channel: Insights into the regulation of extracellular volume and blood pressure

1999 • 34 citations

Human Nedd4 interacts with the human epithelial Na+ channel: WW3 but not WW1 binds to Na+-channel subunits

2000 • 34 citations