Cell surface expression of the epithelial Na channel and a mutant causing Liddle syndrome: A quantitative approach

Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits

1994 • 1,943 citations

Liddle's syndrome: Heritable human hypertension caused by mutations in the β subunit of the epithelial sodium channel

1994 • 1,238 citations

WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome.

1996 • 828 citations

Mutations in subunits of the epithelial sodium channel cause salt wasting with hyperkalaemic acidosis, pseudohypoaldosteronism type 1

1996 • 794 citations

Molecular Genetics of Human Blood Pressure Variation

1996 • 637 citations

Mechanism by which Liddle's syndrome mutations increase activity of a human epithelial Na+ channel

1995 • 408 citations

Identification of a PY motif in the epithelial Na channel subunits as a target sequence for mutations causing channel activation found in Liddle syndrome.

1996 • 397 citations

Membrane topology of the epithelial sodium channel in intact cells

1994 • 311 citations

A mutation in the epithelial sodium channel causing Liddle disease increases channel activity in the Xenopus laevis oocyte expression system.

1995 • 304 citations

Amiloride-sensitive Na channels from the apical membrane of the rat cortical collecting tubule.

1986 • 280 citations

Radiolabeled fragments of monoclonal antibodies against carcinoembryonic antigen for localization of human colon carcinoma grafted into nude mice.

1983 • 256 citations

Cloning and expression of the beta- and gamma-subunits of the human epithelial sodium channel

1995 • 234 citations

The lung amiloride-sensitive Na+ channel: biophysical properties, pharmacology, ontogenesis, and molecular cloning.

1994 • 229 citations

A role for the beta-subunit in the expression of functional Na+-K+-ATPase in Xenopus oocytes

1989 • 228 citations

Membrane topology of the amiloride-sensitive epithelial sodium channel.

1994 • 220 citations

Biochemical analysis of the membrane topology of the amiloride-sensitive Na+ channel.

1994 • 219 citations

Epithelial sodium channels

1994 • 173 citations

Effects of cell Ca and pH on Na channels from rat cortical collecting tubule

1987 • 161 citations

Single-channel recordings from amiloride-sensitive epithelial sodium channel

1985 • 142 citations

Gating of Na channels in the rat cortical collecting tubule: effects of voltage and membrane stretch.

1996 • 111 citations

The highly selective low-conductance epithelial Na channel of Xenopus laevis A6 kidney cells

1995 • 104 citations

Molecular cloning and functional expression of different molecular forms of rat amiloride‐binding proteins

1993 • 57 citations

Blocker-related changes of channel density. Analysis of a three-state model for apical Na channels of frog skin.

1990 • 44 citations

Feedback regulation of Na channels in rat CCT. III. Response to cAMP

1995 • 38 citations

Epithelial sodium channels: characterization by using the patch-clamp technique.

1986 • 31 citations