Elevation of Reactive Oxygen Species following Ischemia-Reperfusion in Mouse Cochlea Observed in vivo

Reactive Oxygen Species and the Central Nervous System

1992 • 2,931 citations

Mitochondrial production of reactive oxygen species in cortical neurons following exposure to N-methyl-D-aspartate

1995 • 779 citations

Carboxyfullerenes as neuroprotective agents

1997 • 724 citations

Ischemia-induced neuronal apoptosis

1996 • 600 citations

Free Radicals and Brain Damage

1993 • 527 citations

Oxidative stress: Free radical production in neural degeneration

1994 • 483 citations

Oxygen free radical involvement in ischemia and reperfusion injury to brain

1988 • 429 citations

Early Elevation of Cochlear Reactive Oxygen Species following Noise Exposure

1999 • 416 citations

Sensitive assay of hydroxyl free radical formation utilizing high pressure liquid chromatography with electrochemical detection of phenol and salicylate hydroxylation products

1984 • 394 citations

Detection of Free Radical Activity During Transient Global Ischemia and Recirculation: Effects of Intraischemic Brain Temperature Modulation

1995 • 388 citations

Aromatic hydroxylation as a potential measure of hydroxyl-radical formation in vivo. Identification of hydroxylated derivatives of salicylate in human body fluids

1986 • 374 citations

A major gene affecting age-related hearing loss in C57BL/6J mice

1997 • 352 citations

EXPERIMENTS ON TEMPORARY OBSTRUCTION OF THE INTERNAL AUDITORY ARTERY.

1959 • 328 citations

Mechanism of Cisplatin Ototoxicity: Antioxidant System

1995 • 320 citations

Brain Temperature Alters Hydroxyl Radical Production during Cerebral Ischemia/Reperfusion in Rats

1996 • 293 citations

Formation of free radicals by gentamicin and iron and evidence for an iron/gentamicin complex

1995 • 286 citations

Direct detection of ototoxicant-induced reactive oxygen species generation in cochlear explants

1996 • 284 citations

Appearance of free radicals in the guinea pig inner ear after noise-induced acoustic trauma

1995 • 280 citations

Hydroxylation of salicylate as an assay for hydroxyl radicals: A cautionary note

1991 • 271 citations

Use of organotypic cultures of Corti's organ to study the protective effects of antioxidant molecules on cisplatin-induced damage of auditory hair cells.

1997 • 262 citations

C57BL/6 strain is most susceptible to cerebral ischemia following bilateral common carotid occlusion among seven mouse strains: selective neuronal death in the murine transient forebrain ischemia

1997 • 235 citations

Excitotoxicity, free radicals, and cell membrane changes

1994 • 228 citations

Brain Hydroxyl Radical Generation in Acute Experimental Head Injury

1993 • 226 citations

Targeted Deletion of the Cytosolic Cu/Zn-Superoxide Dismutase Gene (<i>Sod1</i>) Increases Susceptibility to Noise-Induced Hearing Loss

1999 • 212 citations

The protective effects of allopurinol and superoxide dismutase on noise‐induced cochlear damage

1993 • 207 citations

I Arterial Obstruction of the Labyrinth

1958 • 179 citations

Reactive oxygen species in chick hair cells after gentamicin exposure in vitro

1997 • 176 citations

Genetics of age-related hearing loss in mice. III. Susceptibility of inbred and F1 hybrid strains to noise-induced hearing loss

1996 • 157 citations

Variable efficacy of radical scavengers and iron chelators to attenuate gentamicin ototoxicity in guinea pig in vivo

1996 • 155 citations

Hydroxyl Radicals, Iron, Oxidative Stress, and Neurodegeneration^a

1994 • 141 citations

Attenuation of gentamicin ototoxicity by glutathione in the guinea pig in vivo

1994 • 140 citations

Simultaneous Measurement of Salicylate Hydroxylation and Glutamate Release in the Penumbral Cortex following Transient Middle Cerebral Artery Occlusion in Rats

1996 • 127 citations

Direct effects of intraperilymphatic reactive oxygen species generation on cochlear function

1996 • 112 citations

Effects of carbon monoxide on cochlear electrophysiology and blood flow

1987 • 99 citations

Lipid peroxidation inhibitor attenuates noise-induced temporary threshold shifts

1994 • 94 citations

Murine models of brain aging and age-related neurodegenerative diseases

1997 • 93 citations

Sulfhydryl compounds and antioxidants inhibit cytotoxicity to outer hair cells of a gentamicin metabolite in vitro

1994 • 89 citations

The use of salicylate hydroxylation to detect hydroxyl radical generation in ischemic and traumatic brain injury

1993 • 85 citations

The nature and progression of injury in the organ of Corti during ischemia

1989 • 81 citations

Salicylate, mefenamate, meclofenamate, and quinine on cochlear potentials

1990 • 79 citations

High-Performance Liquid Chromatography-Electrochemical Determination of Salicylate Hydroxylation Products as an in Vivo Marker of Oxidative Stress

1995 • 78 citations

The Protective Effects of Allopurinol and Superoxide Dismutase‐Polyethylene Glycol on Ischemic and Reperfusion‐Induced Cochlear Damage

1991 • 76 citations

Co-expression of NMDA and AMPA/kainate receptor mRNAs in cochlear neurones

1992 • 75 citations

The Protective Effects of Tirilated Mesylate (U74006F) on Ischemic and Reperfusion‐Induced Cochlear Damage

1991 • 68 citations

Intracochlear salicylate reduces low-intensity acoustic and cochlear microphonic distortion products

1992 • 65 citations

A reversible ischemia model in gerbil cochlea

1995 • 62 citations

Differential Hydroxylation of Salicylate in Core and Penumbra Regions During Focal Reversible Cerebral Ischemia

1997 • 53 citations

Implication of non-NMDA and NMDA receptors in cochlear ischemia

1992 • 51 citations

Effects of intra-cochlear perfusion of salicylates on cochlear microphonic and other auditory responses in the guinea pig

1993 • 50 citations

Expression of the major mammalian stress protein in the rat cochlea following transient ischemia

1992 • 43 citations

Detection of Free Radicals by Microdialysis/Spin Trapping Epr Following Focal Cerebral Ischemia-Reperfusion and a Cautionary Note on the Stability of 5,5-Dimethyl-1-Pyrroline N-Oxide (DMPO)

1995 • 41 citations

Effects of Superoxide Dismutase and U74389G on Acute Trimethyltin-Induced Cochlear Dysfunction

1996 • 34 citations

Dynamic response of cochlear blood flow to occlusion of anterior inferior cerebellar artery in guinea pigs

1994 • 32 citations

Contribution of the anterior inferior cerebellar artery to cochlear blood flow in guinea pig: A model-based analysis

1993 • 24 citations

Cochlear blood flow following temporary occlusion of the cerebellar arteries

1990 • 23 citations

The anterior inferior cerebellar arterial network supplying the rat cochlea and its role in autoregulation of cochlear blood flow

1992 • 22 citations

The production of free oxygen radicals and nitric oxide in the rat cochlea

1998 • 21 citations

Myocardial microdialysis of salicylic acid to detect hydroxyl radical generation during ischemia

1995 • 17 citations

Induction of free radicals in the cochlea by an aminoglycoside antibiotic.

1997 • 11 citations

Postmortem Changes in Surface Preparations of the Cochlea

1973 • 9 citations