Brain Temperature Alters Hydroxyl Radical Production during Cerebral Ischemia/Reperfusion in Rats

Elevation of the Extracellular Concentrations of Glutamate and Aspartate in Rat Hippocampus During Transient Cerebral Ischemia Monitored by Intracerebral Microdialysis

1984 • 2,884 citations

Calcium-mediated neurotoxicity: relationship to specific channel types and role in ischemic damage

1988 • 1,745 citations

2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a Neuroprotectant for Cerebral Ischemia

1990 • 1,125 citations

Effect of mild hypothermia on ischemia-induced release of neurotransmitters and free fatty acids in rat brain.

1989 • 1,110 citations

Superoxide dismutases

1989 • 953 citations

Oxidative damage to brain proteins, loss of glutamine synthetase activity, and production of free radicals during ischemia/reperfusion-induced injury to gerbil brain.

1990 • 787 citations

Effect of Ischemia on the In Vivo Release of Striatal Dopamine, Glutamate, and γ‐Aminobutyric Acid Studied by Intracerebral Microdialysis

1988 • 704 citations

Free radical damage to protein and DNA: Mechanisms involved and relevant observations on brain undergoing oxidative stress

1992 • 539 citations

Excitatory amino acid release and free radical formation may cooperate in the genesis of ischemia-induced neuronal damage

1990 • 510 citations

Immature cortical neurons are uniquely sensitive to glutamate toxicity by inhibition of cystine uptake

1990 • 424 citations

The effect of mild hyperthermia and hypothermia on brain damage following 5, 10, and 15 minutes of forebrain ischemia

1990 • 409 citations

Switch in glutamate receptor subunit gene expression in CA1 subfield of hippocampus following global ischemia in rats.

1992 • 399 citations

The Significance of Brain Temperature in Focal Cerebral Ischemia: Histopathological Consequences of Middle Cerebral Artery Occlusion in the Rat

1992 • 353 citations

Effects of normothermic versus mild hyperthermic forebrain ischemia in rats.

1990 • 327 citations

Mitochondrial oxidative stress after carbon monoxide hypoxia in the rat brain.

1992 • 325 citations

Hydroxylation of salicylate as an assay for hydroxyl radicals: A cautionary note

1991 • 271 citations

Intracranial microdialysis of salicylic acid to detect hydroxyl radical generation through dopamine autooxidation in the caudate nucleus: Effects of MPP+

1992 • 234 citations

Free radical generation during brief period of cerebral ischemia may trigger delayed neuronal death

1990 • 216 citations

Temperature Modulation of Cerebral Depolarization during Focal Cerebral Ischemia in Rats: Correlation with Ischemic Injury

1993 • 201 citations

Moderate Hypothermia Reduces Postischemic Edema Development and Leukotriene Production

1987 • 191 citations

Effect of moderate hypothermia on lipid peroxidation in canine brain tissue after cardiac arrest and resuscitation.

1994 • 189 citations

Protection against oxidative damage to CNS by α-phenyl-tert-butyl nitrone (PBN) and other spin-trapping agents: A novel series of nonlipid free radical scavengers

1991 • 183 citations

The effect of profound hypothermia on preservation of cerebral ATP content during circulatory arrest

1968 • 183 citations

Protective effects of brain hypothermia on behavior and histopathology following global cerebral ischemia in rats

1992 • 180 citations

Repeated measurements of cerebral blood flow in rats. Comparisons between the hydrogen clearance method and laser Doppler flowmetry

1988 • 165 citations

Allopurinol and dimethylthiourea reduce brain infarction following middle cerebral artery occlusion in rats.

1989 • 162 citations

Role of dopamine in ischemic striatal injury

1987 • 154 citations

Temperature modulation of ischemic neuronal death and inhibition of calcium/calmodulin-dependent protein kinase II in gerbils.

1990 • 150 citations

Interrelationships between increased vascular permeability and acute neuronal damage following temperature-controlled brain ischemia in rats

1991 • 142 citations

Hydroxyl radical production and lipid peroxidation paralles selective post‐ischemic vulnerability in gerbil brain

1993 • 133 citations

Iron depletion or chelation reduces ischemia/reperfusion-induced edema in gerbil brains

1990 • 112 citations

Pharmacology of Cerebral Ischemia

1992 • 112 citations

Hydrogen Peroxide Production by Monoamine Oxidase during Ischemia-Reperfusion in the Rat Brain

1993 • 108 citations

Hypothermia Attenuates the Loss of Hippocampal Microtubule-Associated Protein 2 (MAP2) following Traumatic Brain Injury

1993 • 104 citations

Regional glucose utilization and blood flow following graded forebrain ischemia in the rat: Correlation with neuropathology

1985 • 95 citations

The biochemical mechanisms of the excitotoxicity of Kainic acid

1992 • 95 citations

Interaction between free radicals and excitatory amino acids in the formation of ischemic brain edema in rats.

1991 • 91 citations

Hypothermia prevents increased capillary permeability following ischemia-reperfusion injury

1988 • 91 citations

Time course of changes in lipid peroxidation, pre- and postsynaptic cholinergic indices, NMDA receptor binding and neuronal death in the gerbil hippocampus following transient ischemia

1991 • 90 citations

Increased excitotoxic vulnerability of cortical cultures with reduced levels of glutathione

1991 • 75 citations

Mitochondrial calcium handling and oxidative stress

1993 • 73 citations

Hyperoxia during reperfusion is a factor in reperfusion injury

1989 • 55 citations

Ischemia-Induced Neurotransmitter Release: Effects of Mild Intraischemic Hyperthermia

1992 • 34 citations

Hypothermia, Metabolic Stress, and NMDA‐Mediated Excitotoxicity

1993 • 33 citations

Prolonged hypothermia in treatment of massive cerebral haemorrhage; a preliminary report.

1956 • 21 citations

Glial contribution to free radical-induced neuronal damage

1993 • 5 citations

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