Substance P and Histamine Induce Interleukin‐6 Expression in Human Astrocytoma Cells by a Mechanism Involving Protein Kinase C and Nuclear Factor‐IL‐6

IκB: a Specific Inhibitor of the NF-κB Transcription Factor

1988 • 2,203 citations

Antioxidant and redox regulation of gene transcription

1996 • 1,999 citations

Cytokine expression in the brain during the acquired immunodeficiency syndrome

1992 • 572 citations

Interleukin-6 in human multiple myeloma

1995 • 550 citations

Interleukin‐6 and α‐2‐macroglobulin indicate an acute‐phase state in Alzheimer's disease cortices

1991 • 484 citations

Human immunodeficiency virus type 1 infection of the nervous system: Pathogenetic mechanisms

1993 • 367 citations

Multiple regulatory elements in the interleukin-6 gene mediate induction by prostaglandins, cyclic AMP, and lipopolysaccharide.

1994 • 325 citations

Redox signalling by transcription factors NF-κB and AP-1 in lymphocytes

1995 • 258 citations

Cytokine indices in Alzheimer's temporal cortex: no changes in mature IL-1β or IL-1RA but increases in the associated acute phase proteins IL-6, α2-macroglobulin and C-reactive protein

1993 • 243 citations

Cytokine mRNA expression in inflammatory multiple sclerosis lesions: Detection by non-radioactive in situ hybridization

1993 • 239 citations

Inflammatory mediators in demyelinating disorders of the CNS and PNS

1992 • 213 citations

Interleukin-6 is present in early stages of plaque formation and is restricted to the brains of Alzheimer's disease patients

1995 • 204 citations

Signal transduction pathways mediating astrocyte IL-6 induction by IL-1 beta and tumor necrosis factor-alpha.

1994 • 193 citations

Amyloid beta peptide potentiates cytokine secretion by interleukin-1 beta-activated human astrocytoma cells.

1995 • 176 citations

Expression of the Alzheimer amyloid-promoting factor antichymotrypsin is induced in human astrocytes by IL-1

1995 • 166 citations

Norepinephrine and vasoactive intestinal peptide induce IL-6 secretion by astrocytes: Synergism with IL-1β and TNFα

1993 • 124 citations

Proinflammatory and Antiinflammatory Cytokines in Multiple Sclerosis and Central Nervous System Acquired Immunodeficiency Syndrome

1992 • 120 citations

Adenosine A_2b Receptors Mediate an Increase in Interleukin (IL)‐6 mRNA and IL‐6 Protein Synthesis in Human Astroglioma Cells

1996 • 115 citations

Prostaglandin E₂ Induces Interleukin‐6 Synthesis in Human Astrocytoma Cells

1997 • 98 citations

Regulation of IL6 gene expression

1992 • 94 citations

Interleukin-6 and its receptor in autoimmunity

1992 • 82 citations

Interleukin-6 secretion from human astrocytoma cells induced by substance P

1994 • 78 citations

Expression of Tumor Necrosis Factor α (TNFα) and Interleukin 6 (IL-6) mRNA in Adult Human Astrocytes

1996 • 75 citations

Cytokine circuits in brain. Implications for AIDS dementia complex.

1994 • 73 citations

Interleukin‐1β Uses Common and Distinct Signaling Pathways for Induction of the Interleukin‐6 and Tumor Necrosis Factor α Genes in the Human Astrocytoma Cell Line U373

1996 • 68 citations

Regulation of the Release of Interleukin‐6 from Human Astrocytoma Cells

1994 • 60 citations

Interleukin‐1β and Tumor Necrosis Factor‐α Induce Expression of α₁‐Antichymotrypsin in Human Astrocytoma Cells by Activation of Nuclear Factor‐κB

1996 • 56 citations

Effects of NSAIDs on IL-1β-induced IL-6 mRNA and protein synthesis in human astrocytoma cells

1996 • 33 citations

Stimulation of the sphingomyelin pathway induces interleukin-6 gene expression in human astrocytoma cells

1995 • 32 citations