Topology of the CD2–CD48 cell-adhesion molecule complex: implications for antigen recognition by T cells

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Structure of the human class I histocompatibility antigen, HLA-A2

1987 • 3,453 citations

T-cell antigen receptor genes and T-cell recognition

1988 • 3,099 citations

Handbook of Experimental Immunology.

1968 • 2,480 citations

Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1

1993 • 2,360 citations

The Immunoglobulin Superfamily—Domains for Cell Surface Recognition

1988 • 2,237 citations

Human Growth Hormone and Extracellular Domain of Its Receptor: Crystal Structure of the Complex

1992 • 2,236 citations

pEF-BOS, a powerful mammalian expression vector

1990 • 1,641 citations

Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide

1994 • 1,553 citations

Molecular cloning of the CD2 antigen, the T-cell erythrocyte receptor, by a rapid immunoselection procedure.

1987 • 949 citations

Real-time biospecific interaction analysis using surface plasmon resonance and a sensor chip technology.

1991 • 909 citations

The structure of protein-protein recognition sites.

1990 • 825 citations

The outline structure of the T-cell alpha beta receptor.

1988 • 625 citations

Atomic structure of a fragment of human CD4 containing two immunoglobulin-like domains

1990 • 549 citations

Crystal structure of an HIV-binding recombinant fragment of human CD4

1990 • 545 citations

Mapping T-cell receptor–peptide contacts by variant peptide immunization of single-chain transgenics

1992 • 531 citations

Comparison of a Structural and a Functional Epitope

1993 • 512 citations

A strategy for the rapid multiple alignment of protein sequences

1987 • 482 citations

The T lymphocyte glycoprotein CD2 binds the cell surface ligand LFA-3

1987 • 453 citations

Domain association in immunoglobulin molecules

1985 • 389 citations

MHC class II interaction with CD4 mediated by a region analogous to the MHC class I binding site for CD8

1992 • 368 citations

Low Affinity Interaction of Peptide-MHC Complexes with T Cell Receptors

1991 • 366 citations

[18] Systematic mutational analyses of protein-protein interfaces

1991 • 345 citations

The Biologic Roles of CD2, CD4, and CD8 in T-Cell Activation

1989 • 301 citations

Crystal structure at 2.8 Å resolution of a soluble form of the cell adhesion molecule CD2

1992 • 295 citations

Preliminary refinement and structural analysis of the Fab fragment from human immunoglobulin new at 2.0 A resolution.

1978 • 293 citations

Helper T cells without CD4: control of leishmaniasis in CD4-deficient mice

1993 • 275 citations

Identification of a CD4 binding site on the β2 domain of HLA-DR molecules

1992 • 272 citations

Crystal structure of a soluble form of the human T cell coreceptor CD8 at 2.6 Å resolution

1992 • 268 citations

The dimensions of the T lymphocyte glycoprotein leukosialin and identification of linear protein epitopes that can be modified by glycosylation.

1991 • 266 citations

A differential-avidity model for T-cell selection

1994 • 239 citations

Identification of human CD4 residues affecting class II MHC versus HIV-1 gp120 binding

1989 • 227 citations

Specific low-affinity recognition of major histocompatibility complex plus peptide by soluble T-cell receptor

1992 • 221 citations

CD48 is a counter-receptor for mouse CD2 and is involved in T cell activation.

1992 • 220 citations

Anchoring mechanisms for LFA-3 cell adhesion glycoprotein at membrane surface

1987 • 220 citations

Transient intercellular adhesion: the importance of weak protein-protein interactions

1994 • 213 citations

Human Cell-Adhesion Molecule CD2 Binds CD58 (LFA-3) with a Very Low Affinity and an Extremely Fast Dissociation Rate but Does Not Bind CD48 or CD59

1994 • 204 citations

Implications of a Fab-like structure for the T-cell receptor

1989 • 193 citations

Specific interaction of lymphocyte function-associated antigen 3 with CD2 can inhibit T cell responses.

1993 • 180 citations

CD43 interferes with T-lymphocyte adhesion.

1992 • 164 citations

Monoclonal antibody and ligand binding sites of the T cell erythrocyte receptor (CD2)

1987 • 143 citations

Secondary, tertiary, and quaternary structure of T-cell-specific immunoglobulin-like polypeptide chains.

1986 • 143 citations

Structure of domain 1 of rat T lymphocyte CD2 antigen

1991 • 142 citations

Crystal Structure of Domains 3 and 4 of Rat CD4: Relation to the NH₂-Terminal Domains

1993 • 142 citations

Crystal structure of the extracellular region of the human cell adhesion molecule CD2 at 2.5å resolution

1994 • 139 citations

Development and function of T cells in mice with a disrupted CD2 gene.

1992 • 134 citations

Targeted disruption of CD43 gene enhances T lymphocyte adhesion.

1993 • 134 citations

Affinity and kinetic analysis of the interaction of the cell adhesion molecules rat CD2 and CD48.

1993 • 115 citations

The cell surface molecule recognized by the erythrocyte receptor of T lymphocytes. Identification and partial characterization using a monoclonal antibody.

1985 • 105 citations

Alloreactive cytotoxic T cells can develop and function in mice lacking both CD4 and CD8

1993 • 101 citations

Structure, expression, and genetic linkage of the mouse BCM1 (OX45 or Blast-1) antigen. Evidence for genetic duplication giving rise to the BCM1 region on mouse chromosome 1 and the CD2/LFA3 region on mouse chromosome 3.

1990 • 95 citations

T‐Lymphocyte Activation: The Biology and Function of CD2 and CD4

1989 • 87 citations

Expression of soluble isoforms of rat CD45. Analysis by electron microscopy and use in epitope mapping of anti-CD45R monoclonal antibodies.

1992 • 87 citations

The CD58 (LFA-3) binding site is a localized and highly charged surface area on the AGFCC'C" face of the human CD2 adhesion domain.

1993 • 81 citations

The MRC OX-45 antigen of rat leukocytes and endothelium is in a subset of the immunoglobulin superfamily with CD2, LFA-3 and carcinoembryonic antigens.

1988 • 74 citations

Blast-1 possesses a glycosyl-phosphatidylinositol (GPI) membrane anchor, is related to LFA-3 and OX-45, and maps to chromosome 1q21-23.

1989 • 72 citations

The NH₂‐terminal domain of rat CD2 binds rat CD48 with a low affinity and binding does not require glycosylation of CD2

1993 • 66 citations

Structure of the glycosylated adhesion domain of human T lymphocyte glycoprotein CD2

1993 • 66 citations

Expression of immunoglobulin and scavenger receptor superfamily domains as chimeric proteins with domains 3 and 4 of CD4 for ligand analysis

1994 • 54 citations

Interaction between human CD2 and CD58 involves the major beta sheet surface of each of their respective adhesion domains.

1994 • 41 citations

The human LFA-3 gene is located at the same chromosome band as the gene for its receptor CD2

1988 • 40 citations

Mutational analysis of the CD2/CD58 interaction: the binding site for CD58 lies on one face of the first domain of human CD2.

1993 • 39 citations

HLA class II antigens and the HIV envelope glycoprotein gp120 bind to the same face of CD4.

1994 • 39 citations

Expression cloning of an equine T‐lymphocyte glycoprotein CD2 cDNA

1994 • 29 citations

Physical linkage of genes encoding the lymphocyte adhesion molecules CD2 and its ligand LFA-3

1989 • 20 citations

Monoclonal antibodies against a rat leucocyte antigen block antigen-induced T-cell responses via an effect on accessory cells.

1986 • 19 citations

Measuring very low affinity interactions between immunoglobulin superfamily cell-adhesion molecules

1993 • 14 citations