Induction of epithelial to mesenchymal transition in PMC42-LA human breast carcinoma cells by carcinoma-associated fibroblast secreted factors
Data up to Jan 2025
Total Citations Per Year
Abstract
References (73)
Epithelial–mesenchymal transitions in tumour progression
2002 • 6,431 citations
Tumors: Wounds That Do Not Heal
1986 • 4,202 citations
Stromal fibroblasts in cancer initiation and progression
2004 • 2,230 citations
Putting tumours in context
2001 • 2,145 citations
E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells.
1991 • 1,592 citations
Presence of modified fibroblasts in granulation tissue and their possible role in wound contraction
1971 • 1,458 citations
Carcinoma-associated fibroblasts stimulate tumor progression of initiated human epithelium
2000 • 1,445 citations
INTERMEDIATE FILAMENTS: Structure, Dynamics, Function and Disease
1994 • 1,408 citations
Role of tissue stroma in cancer cell invasion
2003 • 1,021 citations
Cell surface glycoprotein of reactive stromal fibroblasts as a potential antibody target in human epithelial cancers.
1990 • 677 citations
Identification, purification, and partial sequence analysis of autotaxin, a novel motility-stimulating protein.
1992 • 577 citations
Tumor cell autocrine motility factor.
1986 • 539 citations
Irradiated mammary gland stroma promotes the expression of tumorigenic potential by unirradiated epithelial cells.
2000 • 537 citations
Association of increased basement membrane invasiveness with absence of estrogen receptor and expression of vimentin in human breast cancer cell lines
1992 • 530 citations
E-cadherin binding prevents β-catenin nuclear localization and β-catenin/LEF-1-mediated transactivation
1999 • 526 citations
Molecular cloning of fibroblast activation protein alpha, a member of the serine protease family selectively expressed in stromal fibroblasts of epithelial cancers.
1994 • 522 citations
The multistep nature of cancer development.
1984 • 510 citations
The E-cadherin/catenin complex: an important gatekeeper in breast cancer tumorigenesis and malignant progression
2001 • 453 citations
Monoclonal antibodies specific for vimentin.
1984 • 394 citations
Malignant transformation in a nontumorigenic human prostatic epithelial cell line.
2001 • 343 citations
Expression of smooth muscle-specific proteins in myoepithelium and stromal myofibroblasts of normal and malignant human breast tissue.
1993 • 320 citations
Differentiation state and invasiveness of human breast cancer cell lines
1994 • 260 citations
Antibody targeting in metastatic colon cancer: a phase I study of monoclonal antibody F19 against a cell-surface protein of reactive tumor stromal fibroblasts.
1994 • 240 citations
Cell-surface glycoproteins of human sarcomas: differential expression in normal and malignant tissues and cultured cells.
1988 • 236 citations
Increased content of Type V Collagen in desmoplasia of human breast carcinoma.
1982 • 218 citations
Epithelial (E‐) and placentae (P‐) cadherin cell adhesion molecule expression in breast carcinoma
1993 • 200 citations
Creation of an hepatocyte growth factor/scatter factor autocrine loop in carcinoma cells induces invasive properties associated with increased tumorigenicity.
1994 • 171 citations
Loss of epithelial markers and acquisition of vimentin expression in adriamycin- and vinblastine-resistant human breast cancer cell lines.
1992 • 166 citations
E-cadherin mediates adhesion and suppresses cell motility via distinct mechanisms
1997 • 165 citations
Altered Localization of p120 Catenin During Epithelial to Mesenchymal Transition of Colon Carcinoma Is Prognostic for Aggressive Disease
2005 • 161 citations
Breast fibroblasts modulate epithelial cell proliferation in three-dimensional in vitro co-culture
2004 • 157 citations
Pleiotropic effects of FGFR1 on cell proliferation, survival, and migration in a 3D mammary epithelial cell model
2005 • 146 citations
Suppression of prostate cancer invasive potential and matrix metalloproteinase activity by E-cadherin transfection.
1999 • 141 citations
Collagenase-3 expression in breast myofibroblasts as a molecular marker of transition of ductal carcinoma in situ lesions to invasive ductal carcinomas.
2001 • 135 citations
Epidermal Growth Factor-Induced Epithelio-Mesenchymal Transition in Human Breast Carcinoma Cells
2003 • 132 citations
The plasticity of human breast carcinoma cells is more than epithelial to mesenchymal conversion.
2001 • 118 citations
Matrix-metalloproteinases 1, 2 and 3 and their tissue inhibitors 1 and 2 in benign and malignant breast lesions: an in situ hybridization study
1999 • 112 citations
Cell-adhesion-dependent influences on genomic instability and carcinogenesis
1998 • 101 citations
The role of stroma in breast carcinoma growth in vivo.
1998 • 91 citations
The Epithelial to Mesenchymal Transition and Metastatic Progression in Carcinoma
1996 • 86 citations
Effects of human breast fibroblasts on growth and 17β-estradiol dehydrogenase activity of MCF-7 cells in culture
1988 • 82 citations
New highlights on stroma–epithelial interactions in breast cancer
2004 • 82 citations
A New Human Breast Carcinoma Cell Line (PMC42) With Stem Cell Characteristics. I. Morphologic Characterization
1983 • 76 citations
Angiogenic growth factors in preinvasive breast disease.
1999 • 75 citations
Smooth muscle differentiation in cultured human breast gland stromal cells.
1990 • 67 citations
Growth of normal and neoplastic mouse mammary epithelial cells in primary culture: stimulation by conditioned medium from mouse mammary fibroblasts.
1983 • 67 citations
The potential influence of radiation-induced microenvironments in neoplastic progression.
1998 • 62 citations
Differential regulation of breast tumor cell proliferation by stromal fibroblasts of various breast tissue sources
1996 • 58 citations
Role of tumor‐derived fibroblasts in the growth of primary cultures of human breast‐cancer cells: Effects of epidermal growth factor and the somatostatin analogue octreotide
1995 • 50 citations
Cytoskeleton-associated proteins: their role as cellular integrators in the neoplastic process
1985 • 50 citations
Biomass production of Cymbopogon citratus (D.C.) stapf., a medicinal plant, in temporary immersion systems
2006 • 50 citations
Expression of E-cadherin, α-catenin, and β-catenin in tubulolobular carcinoma of the breast
2006 • 49 citations
Significance of freshly cultured fibroblasts from different tissues in promoting cancer cell growth
1991 • 49 citations
PMC42, A Novel Model for the Differentiated Human Breast
2001 • 45 citations
Fibroblast‐mediated differentiation in human breast carcinoma cells (MCF‐7) grown as nodules IN VITRO
1994 • 45 citations
A New Human Breast Carcinoma Cell Line (PMC42) With Stem Cell Characteristics. III. Hormone Receptor Status and Responsiveness
1984 • 44 citations
Expression of Fibronectin Isoforms in Human Breast Tissue: Production of Extra Domain A+/Extra Domain B+ by Cancer Cells and Extra Domain A+ by Stromal Cells
1999 • 42 citations
Selective interactions between mammary epithelial cells and fibroblasts in co‐culture
1994 • 41 citations
A New Human Breast Carcinoma Cell Line (PMC42) With Stem Cell Characteristics. II. Characterization of Cells Growing as Organoids
1983 • 40 citations
Effect of hepatocyte growth factor/scatter factor and other growth factors on motility and morphology of non-tumorigenic and tumor cells
1994 • 39 citations
Influence of tumor derived fibroblasts and 1,25-dihydroxyvitamin D3 on growth of breast cancer cell lines
1995 • 38 citations
Mammary fibroblasts stimulate growth, alveolar morphogenesis, and functional differentiation of normal rat mammary epithelial cells
2000 • 37 citations
A scatter factor-like factor is produced by a metastatic variant of a rat bladder carcinoma cell line
1994 • 35 citations
Effect of organ-specific fibroblasts on proliferation and differentiation of breast cancer cells
2005 • 31 citations
Positive regulation of normal and tumoral mammary epithelial cell proliferation by fibroblasts in coculture
1998 • 29 citations
Desmoplasia in Benign and Malignant Breast Disease is Characterized by Alterations in Level of mRNAs Coding for Types I and III Procollagen
1991 • 15 citations
Abnormalities of the cadherin-catenin complex in chemically-induced colo-rectal carcinogenesis
2003 • 13 citations
Differential influence of stromal fibroblasts from different breast tissues on human breast tumour cell growth in nude mice.
1993 • 12 citations
Modulations of breast fibroblast and carcinoma cell interactions by a dextran derivative (CMDB7).
1997 • 9 citations
MYOEPITHELIAL MOLECULAR MARKERS IN HUMAN BREAST CARCINOMA PMC42-LA CELLS ARE INDUCED BY EXTRACELLULAR MATRIX AND STROMAL CELLS
2006 • 8 citations
Demonstration of a positive feedback loop of paracrine growth stimulation in a new co-culture model of breast cancer
1993 • 7 citations
[Correlation among expression of E-cadherin, beta-catenin, and cyclin D1 in breast cancers].
2004 • 5 citations
Interactions Between Stroma and Epithelium in Breast Cancer
1999 • 3 citations