Association of Microglia with Amyloid Plaques in Brains of APP23 Transgenic Mice

Glutamate neurotoxicity and diseases of the nervous system

1988 • 7,257 citations

Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice

1996 • 4,118 citations

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

1995 • 2,456 citations

The Fine Structure of the Nervous System.

1970 • 1,971 citations

RAGE and amyloid-β peptide neurotoxicity in Alzheimer's disease

1996 • 1,955 citations

Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

1997 • 1,438 citations

Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease

1996 • 1,371 citations

Amyloid, the presenilins and Alzheimer's disease

1997 • 1,370 citations

Activation of microglial cells by β-amyloid protein and interferon-γ

1995 • 1,298 citations

The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases

1995 • 1,290 citations

Risk of Alzheimer's disease and duration of NSAID use

1997 • 1,113 citations

Relationship of microglia and astrocytes to amyloid deposits of Alzheimer disease

1989 • 904 citations

Alzheimer's Disease--Genotypes, Phenotype, and Treatments

1997 • 884 citations

Microglial Cells Internalize Aggregates of the Alzheimer's Disease Amyloid β-Protein Via a Scavenger Receptor

1996 • 649 citations

ULTRASTRUCTURAL STUDIES IN ALZHEIMER'S PRESENILE DEMENTIA.

1964 • 646 citations

APPSW Transgenic Mice Develop Age-related Aβ Deposits and Neuropil Abnormalities, but no Neuronal Loss in CA1

1997 • 640 citations

Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E

1997 • 601 citations

Microglial response to amyloid plaques in APPsw transgenic mice.

1998 • 580 citations

Aβ Deposition Is Associated with Neuropil Changes, but not with Overt Neuronal Loss in the Human Amyloid Precursor Protein V717F (PDAPP) Transgenic Mouse

1997 • 502 citations

Neurodegenerative Diseases

1994 • 492 citations

Inflammation and Alzheimer's disease pathogenesis

1996 • 444 citations

Brain microglia constitutively express β-2 integrins

1990 • 423 citations

Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein and Alzheimer's disease.

1996 • 373 citations

Amyloid Fibrils Activate Tyrosine Kinase-Dependent Signaling and Superoxide Production in Microglia

1997 • 318 citations

Comparison of Neurodegenerative Pathology in Transgenic Mice Overexpressing V717F β-Amyloid Precursor Protein and Alzheimer’s Disease

1996 • 301 citations

Processing of beta-amyloid precursor protein in microglia and astrocytes favors an internal localization over constitutive secretion

1991 • 276 citations

Specific Domains of β-Amyloid from Alzheimer Plaque Elicit Neuron Killing in Human Microglia

1996 • 268 citations

Ultrastructure of the microglia that phagocytose amyloid and the microglia that produce ?-amyloid fibrils

1992 • 267 citations

Astrocytes Regulate Microglial Phagocytosis of Senile Plaque Cores of Alzheimer's Disease

1998 • 253 citations

Morphologic association between microglia and senile plaque amyloid in Alzheimer's disease

1990 • 238 citations

Role of microglia in senile plaque formation

1995 • 176 citations

Neuronal and microglial involvement in beta-amyloid protein deposition in Alzheimer's disease.

1990 • 175 citations

The complex of microglial cells and amyloid star in three-dimensional reconstruction

1990 • 162 citations

Stereological analysis of astrocyte and microglia in aging mouse hippocampus

1998 • 160 citations

Microglia, Scavenger Receptors, and the Pathogenesis of Alzheimer’s Disease

1998 • 157 citations

Early and rapid de novo synthesis of Alzheimer βA4‐Amyloid precursor protein (APP) in activated microglia

1993 • 129 citations

Phagocytosis of ?/A4 amyloid fibrils of the neuritic neocortical plaques

1991 • 104 citations

Immunohistochemical localization of beta‐amyloid precursor protein sequences in Alzheimer and normal brain tissue by light and electron microscopy

1992 • 88 citations

Ultrastructure of the cells forming amyloid fibers in Alzheimer disease and scrapie

2005 • 78 citations

Age-related deposition of glia-associated fibrillar material in brains of c57BL/6 mice

1994 • 76 citations

β-Amyloid Peptide Secretion by a Microglial Cell Line Is Induced by β-Amyloid-(25–35) and Lipopolysaccharide

1996 • 74 citations

Microglial Response to Transient Focal Cerebral Ischemia: An Immunocytochemical Study on the Rat Cerebral Cortex Using Anti-Phosphotyrosine Antibody

1994 • 61 citations

Amyloid Precursor Protein (APP) in the Striatum in Alzheimerʼs Disease: An Immunohistochemical Study

1993 • 42 citations

Phosphotyrosine antibodies specifically label ameboid microglia in vitro and ramified microglia in vivo

1989 • 38 citations

Alzheimer’s disease: coated vesicles, coated pits and the amyloid-related cell

1988 • 31 citations