Sphingosine-1-Phosphate and Lysophosphatidic Acid Stimulate Endothelial Cell Migration

Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1995 • 4,387 citations

Cell Migration: A Physically Integrated Molecular Process

1996 • 3,909 citations

Angiogenesis.

1992 • 2,581 citations

Rho GTPases Control Polarity, Protrusion, and Adhesion during Cell Movement

1999 • 1,452 citations

Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K

1997 • 746 citations

Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1‐phosphate

1998 • 516 citations

Lysophosphatidic acid: G-protein signalling and cellular responses

1997 • 492 citations

Sphingosine-1-phosphate inhibits PDGF-induced chemotaxis of human arterial smooth muscle cells: spatial and temporal modulation of PDGF chemotactic signal transduction.

1995 • 264 citations

Differential Endothelial Migration and Proliferation to Basic Fibroblast Growth Factor and Vascular Endothelial Growth Factor

1996 • 248 citations

Invasion of T-lymphoma cells: cooperation between Rho family GTPases and lysophospholipid receptor signaling

1998 • 223 citations

Sphingosine 1-phosphate, a specific endogenous signaling molecule controlling cell motility and tumor cell invasiveness.

1992 • 223 citations

Lysophosphatidic Acid and Sphingosine 1-Phosphate Protection of T Cells from Apoptosis in Association with Suppression of Bax

1999 • 219 citations

Assays for angiogenesis: A review

1991 • 202 citations

Role of platelets and thrombosis in mechanisms of acute occlusion and restenosis after angioplasty

1987 • 194 citations

Increasing Complexity of Ras Signal Transduction: Involvement of Rho Family Proteins

1997 • 185 citations

Platelet-derived Growth Factor and Fibronectin-stimulated Migration Are Differentially Regulated by the Rac and Extracellular Signal-regulated Kinase Pathways

1997 • 173 citations

Lysophosphatidic Acid Increases Tight Junction Permeability in Cultured Brain Endothelial Cells

1997 • 172 citations

Release of cAMP Gating by the α6β4 Integrin Stimulates Lamellae Formation and the Chemotactic Migration of Invasive Carcinoma Cells

1998 • 156 citations

A growing family of receptor genes for lysophosphatidic acid (LPA) and other lysophospholipids (LPs)

1999 • 153 citations

The chemotactic response to PDGF-BB: evidence of a role for Ras.

1995 • 116 citations

Modulation of β1A Integrin Functions by Tyrosine Residues in the β1 Cytoplasmic Domain

1998 • 109 citations

Modulation of cell surface fibronectin assembly sites by lysophosphatidic acid.

1994 • 105 citations

Endothelial cell mitogenesis induced by LPA: Inhibition by thrombospondin-1 and thrombospondin-2

1997 • 96 citations

Inhibition of chemotactic motility and trans‐endothelial migration of human neutrophils by sphingosine 1‐phosphate

1997 • 83 citations

Sphingosine 1-Phosphate Stimulates Fibronectin Matrix Assembly Through a Rho-Dependent Signal Pathway

1999 • 73 citations

Lysophosphatidic acid is a chemoattractant for Dictyostelium discoideum amoebae.

1993 • 70 citations

rho-mediated protein tyrosine phosphorylation in lysophosphatidic-acid-induced tumor-cell invasion

1996 • 70 citations

Involvement of Focal Adhesion Kinase in Inhibition of Motility of Human Breast Cancer Cells by Sphingosine 1-Phosphate

1999 • 70 citations

[20] Purification and assay of recombinant C3 transferase

1995 • 62 citations

Signalling properties of lysophosphatidic acid in primary human skin fibroblasts: role of pertussis toxin-sensitive GTP-binding proteins

1996 • 56 citations

Synergism among Lysophosphatidic Acid, β1A Integrins, and Epidermal Growth Factor or Platelet-derived Growth Factor in Mediation of Cell Migration

1999 • 55 citations

Sphingosine 1-Phosphate Stimulates Fibronectin Matrix Assembly Through a Rho-Dependent Signal Pathway

1999 • 19 citations