Cellular and molecular mechanisms of murine autoimmune myocarditis

Signal transduction by lymphocyte antigen receptors

1994 • 2,145 citations

Regulatory T Cell Clones Induced by Oral Tolerance: Suppression of Autoimmune Encephalomyelitis

1994 • 1,995 citations

The Pathophysiology of Tumor Necrosis Factors

1992 • 1,880 citations

Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection

1993 • 1,719 citations

CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones

1992 • 1,573 citations

The B7 and CD28 receptor families

1994 • 1,342 citations

Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy

1992 • 1,290 citations

Differential T Cell Costimulatory Requirements in CD28-Deficient Mice

1993 • 1,271 citations

Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes

1993 • 1,087 citations

Two TNF receptors

1992 • 1,048 citations

Profound block in thymocyte development in mice lacking p56lck

1992 • 965 citations

Viral myocarditis. A review.

1980 • 810 citations

Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions.

1991 • 735 citations

Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4

1991 • 695 citations

An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitis.

1990 • 692 citations

DETECTION OF COXSACKIE-B-VIRUS-SPECIFIC RNA SEQUENCES IN MYOCARDIAL BIOPSY SAMPLES FROM PATIENTS WITH MYOCARDITIS AND DILATED CARDIOMYOPATHY

1986 • 605 citations

Tumour necrosis factor-α in murine autoimmune 'lupus' nephritis

1988 • 599 citations

Active Myocarditis in the Spectrum of Acute Dilated Cardiomyopathies

1985 • 563 citations

Sequences and Factors: A Guide to MHC Class-II Transcription

1992 • 540 citations

CD8 is needed for development of cytotoxic T but not helper T cells

1991 • 528 citations

Myosin isoforms in mammalian skeletal muscle

1994 • 517 citations

Normal B lymphocyte development but impaired T cell maturation in CD45-Exon6 protein tyrosine phosphatase-deficient mice

1993 • 509 citations

Cardiac myosin induces myocarditis in genetically predisposed mice.

1987 • 507 citations

Autoimmune Diseases: The Failure of Self Tolerance

1990 • 495 citations

Unraveling Function in the TNF Ligand and Receptor Families

1994 • 431 citations

Antigen recognition in autoimmune encephalomyelitis and the potential for peptide-mediated immunotherapy

1989 • 394 citations

Involvement of endogenous tumor necrosis factor alpha and transforming growth factor beta during induction of collagen type II arthritis in mice.

1992 • 363 citations

Role of CD8 ⁺ T Cells in Murine Experimental Allergic Encephalomyelitis

1992 • 351 citations

Diagnosis and Classification of Myocarditis by Endomyocardial Biopsy

1983 • 339 citations

Myosin-induced acute myocarditis is a T cell-mediated disease.

1991 • 332 citations

CD28-B7 interactions in T-cell activation

1994 • 315 citations

In situ detection of enteroviral genomes in myocardial cells by nucleic acid hybridization: an approach to the diagnosis of viral heart disease.

1987 • 313 citations

The causes of dilated cardiomyopathy: A clinicopathologic review of 673 consecutive patients

1994 • 301 citations

Effect of tumor necrosis factor alpha on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process.

1994 • 300 citations

TNF, immunity and inflammatory disease: lessons of the past decade.

1995 • 261 citations

Viral infection and the pathogenesis of dilated cardiomyopathy.

1994 • 224 citations

Autoantibodies specific for the cardiac myosin isoform are found in mice susceptible to Coxsackievirus B3-induced myocarditis.

1987 • 224 citations

Interleukin 1 or tumor necrosis factor can promote Coxsackie B3-induced myocarditis in resistant B10.A mice.

1992 • 207 citations

Variations in the susceptibility to Coxsackievirus B3-induced myocarditis among different strains of mice.

1986 • 203 citations

Identification of cardiac myosin peptides capable of inducing autoimmune myocarditis in BALB/c mice.

1996 • 189 citations

Costimulator B7-1 confers antigen-presenting-cell function to parenchymal tissue and in conjunction with tumor necrosis factor alpha leads to autoimmunity in transgenic mice.

1994 • 188 citations

Synergy between anti-CD4 and anti-tumor necrosis factor in the amelioration of established collagen-induced arthritis.

1994 • 188 citations

Molecular Genetic Insights into Cardiovascular Disease

1996 • 184 citations

Diagnostic relevance of humoral and cell-mediated immune reactions in patients with acute viral myocarditis.

1982 • 175 citations

Mice expressing both B7-1 and viral glycoprotein on pancreatic beta cells along with glycoprotein-specific transgenic T cells develop diabetes due to a breakdown of T-lymphocyte unresponsiveness.

1994 • 163 citations

The results of transvenous endomyocardial biopsy can frequently be used to diagnose myocardial diseases in patients with idiopathic heart failure. Endomyocardial biopsies in 100 consecutive patients revealed a substantial incidence of myocarditis.

1984 • 157 citations

Expression of a tumor necrosis factor alpha transgene in murine pancreatic beta cells results in severe and permanent insulitis without evolution towards diabetes.

1992 • 151 citations

T Cell Receptors in Murine Autoimmune Diseases

1989 • 137 citations

Myocarditis-inducing epitope of myosin binds constitutively and stably to I-Ak on antigen-presenting cells in the heart.

1995 • 135 citations

Prevention of experimental encephalomyelitis with peptides that block interaction of T cells with major histocompatibility complex proteins.

1989 • 135 citations

Neutralization of endogenous tumor necrosis factor ameliorates the severity of myosin-induced myocarditis.

1992 • 131 citations

Tumor necrosis factor α in autoimmunity: pretty girl or old witch?

1992 • 128 citations

Expression of myosin-class II major histocompatibility complexes in the normal myocardium occurs before induction of autoimmune myocarditis.

1992 • 126 citations

Reprogramming the Immune System for Peripheral Tolerance with CD4 and CD8 Monoclonal Antibodies

1992 • 124 citations

Autoimmune myocarditis: a paradigm of post-infection autoimmune disease

1988 • 112 citations

Anti‐CD4 Monoclonal Antibodies in Therapy: Creation of Nonclassical Tolerance in the Adult

1992 • 104 citations

Coxsackievirus induced myocarditis in mice: cardiac myosin autoantibodies do not cross-react with the virus.

1987 • 103 citations

Cardiac myosin-induced myocarditis. Heart autoantibodies are not involved in the induction of the disease.

1990 • 103 citations

Class II major histocompatibility complex‐restricted T cell function in CD4‐deficient mice

1994 • 102 citations

Neutralization of endogenous tumor necrosis factor ameliorates the severity of myosin-induced myocarditis.

1992 • 94 citations

Viral Myocarditis Leading to Cardiomyopathy: Do Cytokines Contribute to Pathogenesis?

1993 • 93 citations

Low-Molecular-Weight Tumor Necrosis Factor Receptor p55 Controls Induction of Autoimmune Heart Disease

1997 • 78 citations

The induction of experimental autoimmune myocarditis in mice lacking CD4 or CD8 molecules [corrected]

1993 • 73 citations

Identification of myocarditogenic peptides derived from cardiac myosin capable of inducing experimental allergic myocarditis in the Lewis rat. The utility of a class II binding motif in selecting self-reactive peptides.

1994 • 65 citations

Regulation of MHC expression in vivo. Bacterial lipopolysaccharide induces class I and II MHC products in mouse tissues by a T cell-independent, cyclosporine-sensitive mechanism.

1988 • 59 citations

From Antilymphocyte Serum to Therapeutic Monoclonal Antibodies: First Experiences with a Chimeric CD4 Antibody in the Treatment of Autoimmune Disease

1992 • 59 citations

Muscle-specific gene expression. A comparison of cardiac and skeletal muscle transcription strategies.

1993 • 54 citations

HIV-associated myocarditis. Pathology and immunopathology.

1990 • 54 citations

Cellular infiltrate, major histocompatibility antigen expression and immunopathogenic mechanisms in cardiac myosin-induced myocarditis.

1991 • 54 citations

Serum Cardiac Troponin T and Creatine Kinase–MB Elevations in Murine Autoimmune Myocarditis

1995 • 54 citations

Induction of autoimmunity in the absence of CD28 costimulation.

1996 • 49 citations

Regulation of IFN-gamma and tumor necrosis factor-alpha expression in vivo. Effects of cycloheximide and cyclosporine in normal and lipopolysaccharide-treated mice.

1993 • 49 citations

Cardiac myosin-induced myocarditis: target recognition by autoreactive T cells requires prior activation of cardiac interstitial cells.

1996 • 45 citations

In vivo deposition of myosin-specific autoantibodies in the hearts of mice with experimental autoimmune myocarditis.

1992 • 44 citations

Persistence of virus and viral genome in myocardium after Coxsackievirus B3-induced murine myocarditis

1994 • 35 citations

Experimental allergic encephalomyelitis (EAE) in mice lacking CD4⁺ T cells

1994 • 27 citations

Use of Monoclonal Antibodies in vivo as a Therapeutic Strategy for Alloimmune or Autoimmune Reactivity: The Besançon Experience

1992 • 21 citations

Cellular immune mechanisms in myosin-induced myocarditis

1995 • 11 citations