Rigor-type mutation in the kinesin-related protein HsEg5 changes its subcellular localization and induces microtubule bundling

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.

1985 • 2,456 citations

Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo

1995 • 940 citations

Self-organization of microtubules and motors

1997 • 824 citations

Mitotic spindle organization by a plus-end-directed microtubule motor

1992 • 643 citations

KAR3, a kinesin-related gene required for yeast nuclear fusion

1990 • 504 citations

Dynactin, a conserved, ubiquitously expressed component of an activator of vesicle motility mediated by cytoplasmic dynein.

1991 • 482 citations

Microtubules Orient the Mitotic Spindle in Yeast through Dynein-dependent Interactions with the Cell Cortex

1997 • 468 citations

CENP-E is a putative kinetochore motor that accumulates just before mitosis

1992 • 424 citations

Mutation of a gene that encodes a kinesin-like protein blocks nuclear division in A. nidulans

1990 • 404 citations

Two Saccharomyces cerevisiae kinesin-related gene products required for mitotic spindle assembly.

1992 • 401 citations

A three-domain structure of kinesin heavy chain revealed by DNA sequence and microtubule binding analyses

1989 • 392 citations

Novel potential mitotic motor protein encoded by the fission yeast cut7+ gene

1990 • 366 citations

A bipolar kinesin

1996 • 365 citations

Kinesin-related proteins required for assembly of the mitotic spindle.

1992 • 347 citations

Evidence for alternating head catalysis by kinesin during microtubule-stimulated ATP hydrolysis.

1994 • 344 citations

Cytoplasmic dynein plays a role in mammalian mitotic spindle formation.

1993 • 335 citations

Mutations of p34cdc2 phosphorylation sites induce premature mitotic events in HeLa cells: evidence for a double block to p34cdc2 kinase activation in vertebrates.

1991 • 318 citations

Opposing motor activities are required for the organization of the mammalian mitotic spindle pole.

1996 • 301 citations

The kinesin-like protein KLP61F is essential for mitosis in Drosophila.

1993 • 299 citations

Targeting of Motor Proteins

1996 • 278 citations

Yeast Kar3 is a minus-end microtubule motor protein that destabilizes microtubules preferentially at the minus ends.

1994 • 271 citations

Mutations in the kinesin-like protein Eg5 disrupting localization to the mitotic spindle.

1995 • 269 citations

Kinesin-related cut 7 protein associates with mitotic and meiotic spindles in fission yeast

1992 • 262 citations

Pathway of processive ATP hydrolysis by kinesin

1995 • 249 citations

Point mutation of adenosine triphosphate-binding motif generated rigor kinesin that selectively blocks anterograde lysosome membrane transport.

1995 • 230 citations

Expression of tau protein in non-neuronal cells: microtubule binding and stabilization

1992 • 215 citations

Saccharomyces cerevisiae kinesin- and dynein-related proteins required for anaphase chromosome segregation.

1995 • 209 citations

Protein localization to the nucleolus: a search for targeting domains in nucleolin

1993 • 209 citations

Analysis of MAP 4 function in living cells using green fluorescent protein (GFP) chimeras.

1995 • 195 citations

Interacting Head Mechanism of Microtubule-Kinesin ATPase

1997 • 182 citations

Failure of a single-headed kinesin to track parallel to microtubule protofilaments

1995 • 173 citations

Xklp2, a Novel Xenopus Centrosomal Kinesin-like Protein Required for Centrosome Separation during Mitosis

1996 • 159 citations

Mitotic Regulation of Microtubule Cross-Linking Activity of CENP-E Kinetochore Protein

1994 • 148 citations

Phosphorylation by p34cdc2 Protein Kinase Regulates Binding of the Kinesin-related Motor HsEg5 to the Dynactin Subunit p150Glued

1997 • 145 citations

Cloning by Differential Screening of a Xenopus cDNA That Encodes a Kinesin-Related Protein

1991 • 143 citations

Suppression of the bimC4 mitotic spindle defect by deletion of klpA, a gene encoding a KAR3-related kinesin-like protein in Aspergillus nidulans.

1993 • 138 citations

Mutants of the Drosophila ncd microtubule motor protein cause centrosomal and spindle pole defects in mitosis

1994 • 128 citations

Localization of the Kar3 kinesin heavy chain-related protein requires the Cik1 interacting protein

1994 • 124 citations

Kinesin-Related Proteins at Mitotic Spindle Poles: Function and Regulation

1996 • 121 citations

Cloning by differential screening of a Xenopus cDNA that encodes a kinesin-related protein.

1991 • 118 citations

The force-producing mechanism for centrosome separation during spindle formation in vertebrates is intrinsic to each aster

1993 • 112 citations

Opposite Effects of Electrostatics and Steric Exclusion on Bundle Formation by F-Actin and Other Filamentous Polyelectrolytes

1997 • 110 citations

Competition between motor molecules (kinesin and cytoplasmic dynein) and fibrous microtubule-associated proteins in binding to microtubules.

1994 • 109 citations

Chromosomes take the lead in spindle assembly

1995 • 83 citations

Stable expression of heterologous microtubule-associated proteins (MAPs) in Chinese hamster ovary cells: evidence for differing roles of MAPs in microtubule organization.

1994 • 75 citations

Kinesin and ncd Bind Through a Single Head to Microtubules and Compete for a Shared MT Binding Site

1995 • 72 citations

The lethal(1)TW-6cs mutation of Drosophila melanogaster is a dominant antimorphic allele of nod and is associated with a single base change in the putative ATP-binding domain.

1991 • 70 citations

Kinetics and Motility of the Eg5 Microtubule Motor

1996 • 65 citations

The Kinesin-Related Protein Eg5 Associates with both Interphase and Spindle Microtubules during Xenopus Early Development

1994 • 54 citations

Chromosome motion in mitosis

1992 • 44 citations

Single kinesin molecules crossbridge microtubules in vitro.

1993 • 40 citations

Microinjection of intact MAP-4 and fragments induces changes of the cytoskeleton in PtK2 cells

1996 • 23 citations

Enhancement of the ncd D microtubule motor mutant by mutants of αTub67C

1997 • 16 citations

Making a connection: The “other” microtubule end

1996 • 8 citations