Chromosome motion in mitosis

Molecular Cell Biology

2002 • 1,145 citations

Polewards microtubule flux in the mitotic spindle: evidence from photoactivation of fluorescence.

1989 • 603 citations

γ-Tubulin is a highly conserved component of the centrosome

1991 • 566 citations

γ-tubulin is a component of the spindle pole body that is essential for microtubule function in Aspergillus nidulans

1990 • 558 citations

Mitosis and the Physiology of Cell Division

1961 • 549 citations

Localization of cytoplasmic dynein to mitotic spindles and kinetochores

1990 • 508 citations

KAR3, a kinesin-related gene required for yeast nuclear fusion

1990 • 504 citations

Tubulin dynamics in cultured mammalian cells.

1984 • 489 citations

Kinetochores are transported poleward along a single astral microtubule during chromosome attachment to the spindle in newt lung cells.

1990 • 488 citations

Cytoplasmic dynein is localized to kinetochores during mitosis

1990 • 486 citations

Real-time visualization of cell cycle-dependent changes in microtubule dynamics in cytoplasmic extracts

1990 • 444 citations

Identification of dynamin, a novel mechanochemical enzyme that mediates interactions between microtubules

1989 • 436 citations

The Formation, Structure, and Composition of the Mammalian Kinetochore and Kinetochore Fiber

1982 • 428 citations

Sites of microtubule assembly and disassembly in the mitotic spindle

1986 • 410 citations

Polewards chromosome movement driven by microtubule depolymerization in vitro

1988 • 409 citations

γ-Tubulin is present in Drosophila melanogaster and homo sapiens and is associated with the centrosome

1991 • 405 citations

Mutation of a gene that encodes a kinesin-like protein blocks nuclear division in A. nidulans

1990 • 404 citations

Novel potential mitotic motor protein encoded by the fission yeast cut7+ gene

1990 • 366 citations

The Drosophila claret segregation protein is a minus-end directed motor molecule

1990 • 345 citations

The kinesin-like ncd protein of Drosophila is a minus end-directed microtubule motor

1990 • 335 citations

Variant Mitoses in Lower Eukaryotes: Indicators of the Evolution of Mitosis?

1980 • 323 citations

Chromosomes move poleward in anaphase along stationary microtubules that coordinately disassemble from their kinetochore ends.

1987 • 314 citations

Kinetochores capture astral microtubules during chromosome attachment to the mitotic spindle: direct visualization in live newt lung cells.

1990 • 312 citations

Oscillatory movements of monooriented chromosomes and their position relative to the spindle pole result from the ejection properties of the aster and half-spindle.

1986 • 302 citations

Identification of kinesin in sea urchin eggs, and evidence for its localization in the mitotic spindle

1985 • 301 citations

Polarized Intracellular Particle Transport: Saltatory Movements and Cytoplasmic Streaming

1972 • 267 citations

Monoclonal antibodies to kinesin heavy and light chains stain vesicle-like structures, but not microtubules, in cultured cells.

1989 • 261 citations

Mediation of meiotic and early mitotic chromosome segregation in Drosophila by a protein related to kinesin

1990 • 229 citations

Multiple nucleotide-binding sites in the sequence of dynein β heavy chain

1991 • 229 citations

Microtubule depolymerization promotes particle and chromosome movement in vitro.

1991 • 215 citations

Two different microtubule-based motor activities with opposite polarities in kinetochores

1991 • 202 citations

Kinesin heavy chain is essential for viability and neuromuscular functions in Drosophila, but mutants show no defects in mitosis

1991 • 197 citations

Rethinking mitosis

1982 • 195 citations

Microtubule-nucleating activity of centrosomes in Chinese hamster ovary cells is independent of the centriole cycle but coupled to the mitotic cycle.

1981 • 191 citations

Poleward microtubule flux mitotic spindles assembled in vitro.

1991 • 184 citations

Four ATP-binding sites in the midregion of the β heavy chain of dynein

1991 • 175 citations

Formation of spindle fibers, kinetochore orientation, and behavior of the nuclear envelope during mitosis in endosperm

1969 • 156 citations

Mitosis : molecules and mechanisms

1989 • 153 citations

Isolation of mitotic apparatus containing vesicles with calcium sequestration activity

1980 • 148 citations

Microtubule dynamics and chromosome motion visualized in living anaphase cells.

1988 • 147 citations

Movement and segregation of kinetochores experimentally detached from mammalian chromosomes

1988 • 146 citations

Functional autonomy of monopolar spindle and evidence for oscillatory movement in mitosis.

1982 • 145 citations

Respective roles of centrosomes and chromatin in the conversion of microtubule arrays from interphase to metaphase.

1984 • 115 citations

Subcellular localization and sequence of sea urchin kinesin heavy chain: evidence for its association with membranes in the mitotic apparatus and interphase cytoplasm [published erratum appears in J Cell Biol 1991 Aug;114(4):following 863]

1991 • 112 citations

Molecular cell biology, 2nd edn

1990 • 111 citations

The Cell in Development and Heredity

1925 • 107 citations

AN INTERPRETATION OF TRANSPORT PHENOMENA AT MITOSIS*

1960 • 107 citations

Chemical subdomains within the kinetochore domain of isolated CHO mitotic chromosomes.

1991 • 107 citations

Localization of kinesin in cultured cells.

1988 • 107 citations

Analysis of the treadmilling model during metaphase of mitosis using fluorescence redistribution after photobleaching.

1986 • 106 citations

THE CELL: Biochemistry, Physiology, Morphology

1961 • 101 citations

Microtubules of the kinetochore fiber turn over in metaphase but not in anaphase.

1989 • 93 citations

The distribution of calmodulin in living mitotic cells

1983 • 90 citations

Calcium and calmodulin-dependent phosphorylation of a 62 kd protein induces microtubule depolymerization in sea urchin mitotic apparatuses

1988 • 86 citations

A dynamin-like protein encoded by the yeast sporulation gene SP015

1991 • 80 citations

Chromosome motion and the spindle matrix.

1984 • 70 citations

Meiosis and early cleavage in Drosophila melanogaster eggs: Effects of the claret-non-disjunctional mutation

1983 • 64 citations

Cine-micrographic studies on chromosome movements inβ-irradiated cells

1957 • 62 citations

Microtubules in the metaphase-arrested mouse oocyte turn over rapidly.

1990 • 59 citations

Distributive segregation: Motors in the polar wind?

1991 • 57 citations

On the mechanism of anaphase A: evidence that ATP is needed for microtubule disassembly and not generation of polewards force.

1987 • 53 citations

Mechanically cut mitotic spindles: clean cuts and stable microtubules

1989 • 51 citations

Separation of meiotic and mitotic effects of claret non-disjunctional on chromosome segregation in Drosophila.

1991 • 49 citations

Microinjection of antibodies to a 62 kd mitotic apparatus protein arrests mitosis in dividing sea urchin embryos

1989 • 47 citations

Centromeres and kinetochores: integrated domains on eukaryotic chromosomes

1990 • 39 citations

Ciné-micrographic studies on mitosis in endosperm

1958 • 31 citations

In vitro reactivation of anaphase B in isolated spindles of the sea urchin egg

1988 • 30 citations

Characterization of mitotic motors by their relative sensitivity to amp-pnp

1989 • 22 citations

Spoke: a 120-kD protein associated with a novel filamentous structure on or near kinetochore microtubules in the mitotic spindle.

1991 • 20 citations

Non-kinetochore transport phenomena, microtubule ? chromosome associations, and force transmission in nuclear division

1990 • 17 citations

Location of the motive force for chromosome movement in sand dollar eggs

1982 • 13 citations