Characterization of an NF-1/CTF Family Member as a Functional Activator of the Mouse Mammary Tumor Virus Long Terminal Repeat 5′ Enhancer

Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome

1982 • 1,790 citations

A cellular DNA-binding protein that activates eukaryotic transcription and DNA replication

1987 • 1,050 citations

Luciferase reporter gene vectors for analysis of promoters and enhancers.

1988 • 1,016 citations

Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes

1984 • 906 citations

Wnt genes

1992 • 799 citations

A family of human CCAAT-box-binding proteins active in transcription and DNA replication: cloning and expression of multiple cDNAs

1988 • 747 citations

Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice

1988 • 745 citations

A multiplicity of CCAAT box-binding proteins

1987 • 745 citations

Human CCAAT-binding proteins have heterologous subunits

1988 • 712 citations

Sequence-specific binding of glucocorticoid receptor to MTV DNA at sites within and upstream of the transcribed region

1983 • 700 citations

Identification of a rat liver nuclear protein that binds to the enhancer core element of three animal viruses.

1987 • 631 citations

Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15

1984 • 609 citations

Homologous recognition of a promoter domain common to the MSV LTR and the HSV tk gene

1986 • 562 citations

The hormone regulatory element of mouse mammary tumour virus mediates progesterone induction.

1986 • 406 citations

Tumorigenesis by mouse mammary tumor virus: Proviral activation of a cellular gene in the common integration region int-2

1984 • 356 citations

Specific binding of a cellular DNA replication protein to the origin of replication of adenovirus DNA.

1983 • 318 citations

Glucocorticoid regulation of the Ha-MuSV p21 gene conferred by sequences from mouse mammary tumor virus

1981 • 303 citations

The hormone response element of the mouse mammary tumour virus DNA mediates the progestin and androgen induction of transcription in the proviral long terminal repeat region.

1987 • 275 citations

Structure and nucleotide sequence of the putative mammary oncogene int-1; proviral insertions leave the protein-encoding domain intact

1984 • 222 citations

The TGGCA-binding protein: a eukaryotic nuclear protein recognizing a symmetrical sequence on double-stranded linear DNA

1984 • 191 citations

DNA sequences outside the receptor-binding sites differently modulate the responsiveness of the mouse mammary tumour virus promoter to various steroid hormones.

1988 • 184 citations

Multiple genes encode nuclear factor 1-like proteins that bind to the promoter for 3-hydroxy-3-methylglutaryl-coenzyme A reductase.

1988 • 171 citations

Interaction of the TGGCA-binding protein with upstream sequences is required for efficient transcription of mouse mammary tumor virus.

1987 • 168 citations

Distinct sequence elements involved in the glucocorticoid regulation of the mouse mammary tumor virus promoter identified by linker scanning mutagenesis

1986 • 158 citations

Recognition site of nuclear factor I, a sequence-specific DNA-binding protein from HeLa cells that stimulates adenovirus DNA replication.

1985 • 148 citations

Concerted activation of two potential proto-oncogenes in carcinomas induced by mouse mammary tumour virus

1986 • 137 citations

Transcription factor nuclear factor I proteins form stable homo‐ and heterodimers

1994 • 135 citations

A mammary cell-specific enhancer in mouse mammary tumor virus DNA is composed of multiple regulatory elements including binding sites for CTF/NFI and a novel transcription factor, mammary cell-activating factor.

1992 • 117 citations

Sequence-specific interactions of nuclear factors with conserved sequences of human class II major histocompatibility complex genes.

1987 • 103 citations

trans-activation of the alpha 1-acid glycoprotein gene acute phase responsive element by multiple isoforms of C/EBP and glucocorticoid receptor

1993 • 102 citations

Glucocorticoid regulation of transcription at an amplified, episomal promoter.

1983 • 88 citations

Two Regions of the Mouse Mammary Tumor Virus Long Terminal Repeat Regulate the Activity of Its Promoter in Mammary Cell Lines

1991 • 88 citations

Factors controlling the expression of mouse mammary tumour virus

1992 • 85 citations

Endogenous mouse mammary tumor virus is expressed in several organs in addition to the lactating mammary gland

1988 • 75 citations

Multiple regulatory domains in the mouse mammary tumor virus long terminal repeat revealed by analysis of fusion genes in transgenic mice.

1988 • 70 citations

The human alpha subunit glycoprotein hormone gene utilizes a unique CCAAT binding factor.

1990 • 64 citations

Negative regulation in correct tissue-specific expression of mouse mammary tumor virus in transgenic mice.

1990 • 60 citations

Dual function of a nuclear factor I binding site in MMTV transcription regulation

1989 • 54 citations

Oncogene activation and oncogene cooperation in MMTV-induced mouse mammary cancer

1995 • 52 citations

A mouse mammary tumor virus mammary gland enhancer confers tissue-specific but not lactation-dependent expression in transgenic mice

1992 • 45 citations

Identification of a novel mammary cell line-specific enhancer element in the long terminal repeat of mouse mammary tumor virus, which interacts with its hormone-responsive element

1991 • 36 citations

High frequency variation in mammary tumor virus expression in cell culture

1976 • 34 citations

Oncogene expression during progression of mouse mammary tumor cells; activity of a proviral enhancer and the resulting expression of int-2 is influenced by the state of differentiation.

1987 • 33 citations

Involvement of a C/EBP-like Protein in the Acquisition of Responsiveness to Glucocorticoid Hormones during Chick Neural Retina Development

1993 • 31 citations

The 5' enhancer of the mouse mammary tumor virus long terminal repeat contains a functional AP-2 element.

1994 • 23 citations

Efficient solubilization and partial purification of sea urchin histone genes as chromatin

1985 • 16 citations

Role of the TATA box in transcription of the mouse mammary tumor virus long terminal repeat.

1995 • 8 citations