DNA sequences outside the receptor-binding sites differently modulate the responsiveness of the mouse mammary tumour virus promoter to various steroid hormones.

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

pEMBL: a new family of single stranded plasmids

1983 • 1,231 citations

Identification of two distinct regulatory regions adjacent to the human β-interferon gene

1983 • 1,076 citations

Positive and negative regulation of transcription in vitro: Enhancer-binding protein AP-2 is inhibited by SV40 T antigen

1987 • 969 citations

Oligonucleotide-Directed Mutagenesis: A Simple Method Using Two Oligonucleotide Primers and a Single-Stranded DNA Template

1984 • 947 citations

Functional domains of the human glucocorticoid receptor

1986 • 933 citations

Multiple Point Mutations Affecting the Simian Virus 40 Enhancer

1983 • 883 citations

Activation of transcription by two factors that bind promoter and enhancer sequences of the human metallothionein gene and SV40

1987 • 762 citations

Cooperativity of glucocorticoid response elements located far upstream of the tyrosine aminotransferase gene

1987 • 760 citations

Sequence-specific binding of glucocorticoid receptor to MTV DNA at sites within and upstream of the transcribed region

1983 • 700 citations

DNA sequences bound specifically by glucocorticoid receptor in vitro render a heterologous promoter hormone responsive in vivo

1983 • 692 citations

Identification of a rat liver nuclear protein that binds to the enhancer core element of three animal viruses.

1987 • 631 citations

The glucocorticoid receptor binds to defined nucleotide sequences near the promoter of mouse mammary tumour virus

1983 • 619 citations

Protein-Binding Sites in Ig Gene Enhancers Determine Transcriptional Activity and Inducibility

1987 • 619 citations

Sequence-specific positioning of nucleosomes over the steroid-inducible MMTV promoter.

1987 • 597 citations

Enhancer elements

1983 • 576 citations

Colocalization of DNA-binding and transcriptional activation functions in the human glucocorticoid receptor

1987 • 512 citations

The hormone regulatory element of mouse mammary tumour virus mediates progesterone induction.

1986 • 406 citations

Glucocorticoid and progesterone receptors bind to the same sites in two hormonally regulated promoters

1985 • 366 citations

Carcinogenesis: A superfamily of potentially oncogenic hormone receptors

1986 • 324 citations

Dexamethasone-mediated induction of mouse mammary tumor virus RNA: a system for studying glucocorticoid action

1975 • 284 citations

The hormone response element of the mouse mammary tumour virus DNA mediates the progestin and androgen induction of transcription in the proviral long terminal repeat region.

1987 • 275 citations

Six distinct nuclear factors interact with the 75-base-pair repeat of the Moloney murine leukemia virus enhancer.

1987 • 259 citations

A small region of the mouse mammary tumor virus long terminal repeat confers glucocorticoid hormone regulation on a linked heterologous gene.

1983 • 213 citations

Steroid hormone receptors : structure and function

1983 • 210 citations

The TGGCA protein binds to the MMTV-LTR, the adenovirus origin of replication, and the BK virus enhancer

1985 • 203 citations

The TGGCA-binding protein: a eukaryotic nuclear protein recognizing a symmetrical sequence on double-stranded linear DNA

1984 • 191 citations

Interaction of the TGGCA-binding protein with upstream sequences is required for efficient transcription of mouse mammary tumor virus.

1987 • 168 citations

Hormonal response region in the mouse mammary tumor virus long terminal repeat can be dissociated from the proviral promoter and has enhancer properties.

1985 • 164 citations

Distinct sequence elements involved in the glucocorticoid regulation of the mouse mammary tumor virus promoter identified by linker scanning mutagenesis

1986 • 158 citations

Hybrid plasmids containing an active thymidine kinase gene of Herpes simplex virus 1

1979 • 147 citations

Six Distinct Nuclear Factors Interact with the 75-Base-Pair Repeat of the Moloney Murine Leukemia Virus Enhancer

1987 • 146 citations

Androgen regulation by the long terminal repeat of mouse mammary tumor virus.

1986 • 138 citations

One cell-specific and three ubiquitous nuclear proteins bind in vitro to overlapping motifs in the domain B1 of the SV40 enhancer.

1987 • 127 citations

Glucocorticoid-receptor interaction and induction of murine mammary tumor virus.

1975 • 76 citations

Nuclear proteins form lactating mammary glands bind to the promoter of a milk protein gene

1987 • 73 citations