Platelet Derived Growth Factor (PDGF) autocrine components in human tumor cell lines

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

The biology of platelet-derived growth factor

1986 • 2,036 citations

Simian Sarcoma Virus onc Gene, v- sis , Is Derived from the Gene (or Genes) Encoding a Platelet-Derived Growth Factor

1983 • 1,550 citations

Early Signals in the Mitogenic Response

1986 • 1,498 citations

Autocrine growth factors and cancer

1985 • 1,462 citations

Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors

1986 • 1,244 citations

Transforming Growth Factor-β: Biological Function and Chemical Structure

1986 • 1,198 citations

cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines

1986 • 786 citations

The Action of Oncogenes in the Cytoplasm and Nucleus

1985 • 708 citations

Cellular genes analogous to retroviral onc genes are transcribed in human tumour cells

1982 • 507 citations

Use of synthetic oligonucleotides as hybridization probes: isolation of cloned cDNA sequences for human beta 2-microglobulin.

1981 • 423 citations

Sarcoma growth factor from conditioned medium of virally transformed cells is composed of both type alpha and type beta transforming growth factors.

1983 • 381 citations

The c-sis gene encodes a precursor of the B chain of platelet-derived growth factor.

1984 • 376 citations

Expression of insulin-like growth factor-II transcripts in Wilms' tumour

1985 • 352 citations

Transforming protein of simian sarcoma virus stimulates autocrine growth of SSV-transformed cells through PDGF cell-surface receptors

1984 • 277 citations

Efficient reversion of simian sarcoma virus-transformation and inhibition of growth factor-induced mitogenesis by suramin.

1986 • 270 citations

Autocrine Stimulation of Intracellular PDGF Receptors in v- sis -Transformed Cells

1988 • 267 citations

Expression of a Platelet-Derived Growth Factor-Like Protein in Simian Sarcoma Virus Transformed Cells

1983 • 246 citations

Thrombin stimulates c-sis gene expression in microvascular endothelial cells.

1986 • 235 citations

Production of platelet-derived growth factor-like molecules and reduced expression of platelet-derived growth factor receptors accompany transformation by a wide spectrum of agents.

1984 • 233 citations

Human transforming growth factor. Production by a melanoma cell line, purification, and initial characterization.

1982 • 223 citations

Antibodies against platelet-derived growth factor inhibit acute transformation by simian sarcoma virus

1985 • 205 citations

Human melanoma cell lines of primary and metastatic origin express the genes encoding the chains of platelet-derived growth factor (PDGF) and produce a PDGF-like growth factor.

1986 • 187 citations

Expression of the normal human sis/PDGF-2 coding sequence induces cellular transformation

1984 • 170 citations

Nucleotide sequence analysis identifies the human c-sis proto-oncogene as a structural gene for platelet-derived growth factor

1984 • 170 citations

Blockade of autocrine stimulation in simian sarcoma virus-transformed cells reverses down-regulation of platelet-derived growth factor receptors.

1984 • 163 citations

Evidence That the v- sis Gene Product Transforms by Interaction with the Receptor for Platelet-Derived Growth Factor

1985 • 138 citations

Transforming Potential of Human c- sis Nucleotide Sequences Encoding Platelet-Derived Growth Factor

1984 • 127 citations

Regulated expression of the platelet-derived growth factor A chain gene in microvascular endothelial cells.

1987 • 126 citations

Synthesis and secretion of proteins resembling platelet-derived growth factor by human glioblastoma and fibrosarcoma cells in culture.

1985 • 125 citations

Processing of the platelet-derived growth factor receptor. Biosynthetic and degradation studies using anti-receptor antibodies.

1987 • 110 citations

Anchorage‐independent growth of primary rat embryo cells is induced by platelet‐derived growth factor and inhibited by type‐beta transforming growth factor

1986 • 108 citations

Bombesin-like peptides and receptors in human tumor cell lines

1983 • 103 citations

A Common PDGF rEceptor Is Activated by Homodimeric A and B Forms of PDGF

1988 • 85 citations

Stem cell studies of human malignant brain tumors

1983 • 80 citations

Expression of c-sis and Platelet-Derived Growth Factor in in Vitro-Transformed Glioma Cells from Rat Brain Tissue Transplacentally Treated with Ethylnitrosourea

1986 • 23 citations

Oncogene-related growth factors and growth factor receptors in human malignant glioma-derived cell lines

1989 • 20 citations