Oncogene-related growth factors and growth factor receptors in human malignant glioma-derived cell lines

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences

1984 • 2,564 citations

CELLULAR ONCOGENES AND RETROVIRUSES

1983 • 1,671 citations

Simian Sarcoma Virus onc Gene, v- sis , Is Derived from the Gene (or Genes) Encoding a Platelet-Derived Growth Factor

1983 • 1,550 citations

Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin

1985 • 1,523 citations

Autocrine growth factors and cancer

1985 • 1,462 citations

Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors

1986 • 1,244 citations

Cellular Oncogenes and Multistep Carcinogenesis

1983 • 1,154 citations

PLATELET-DERIVED GROWTH FACTOR

1989 • 967 citations

Growth factors: Mechanism of action and relation to oncogenes

1984 • 885 citations

Visualization by fluorescence of the binding and internalization of epidermal growth factor in human carcinoma cells A-431.

1978 • 578 citations

Cellular genes analogous to retroviral onc genes are transcribed in human tumour cells

1982 • 507 citations

Expression of epidermal growth factor receptors in human brain tumors.

1984 • 478 citations

Specific receptors for platelet-derived growth factor on cells derived from connective tissue and glia.

1981 • 427 citations

Transforming protein of simian sarcoma virus stimulates autocrine growth of SSV-transformed cells through PDGF cell-surface receptors

1984 • 277 citations

Chromosomal Localization of the Human Homolog (c- sis ) of the Simian Sarcoma Virus onc Gene

1982 • 262 citations

Thrombin stimulates c-sis gene expression in microvascular endothelial cells.

1986 • 235 citations

Production of platelet-derived growth factor-like molecules and reduced expression of platelet-derived growth factor receptors accompany transformation by a wide spectrum of agents.

1984 • 233 citations

Platelet-derived growth factor

1985 • 226 citations

Evidence for the platelet-derived growth factor-stimulated tyrosine phosphorylation of the platelet-derived growth factor receptor in vivo. Immunopurification using a monoclonal antibody to phosphotyrosine.

1984 • 209 citations

Platelet-derived growth factor receptors form a high affinity state in membrane preparations. Kinetics and affinity cross-linking studies.

1984 • 207 citations

Antibodies against platelet-derived growth factor inhibit acute transformation by simian sarcoma virus

1985 • 205 citations

A glioma-derived analog to platelet-derived growth factor: demonstration of receptor competing activity and immunological crossreactivity.

1984 • 160 citations

Density dependent proliferation of human glia cells stimulated by epidermal growth factor

1976 • 150 citations

Evidence That the v- sis Gene Product Transforms by Interaction with the Receptor for Platelet-Derived Growth Factor

1985 • 138 citations

Simian Sarcoma Virus—Transformed Cells Secrete a Mitogen Identical to Platelet-Derived Growth Factor

1984 • 137 citations

Detection of c- sis Transcripts and Synthesis of PDGF-Like Proteins by Human Osteosarcoma Cells

1984 • 134 citations

Antibody guided irradiation of brain glioma by arterial infusion of radioactive monoclonal antibody against epidermal growth factor receptor and blood group A antigen.

1985 • 134 citations

Patterns of the early, gross chromosomal changes in malignant human gliomas

2008 • 131 citations

A model of cell cycle control: Sequential events regulated by growth factors

1983 • 127 citations

Synthesis and secretion of proteins resembling platelet-derived growth factor by human glioblastoma and fibrosarcoma cells in culture.

1985 • 125 citations

Synthesis of a PDGF-like growth factor in human glioma and sarcoma cells suggests the expression of the cellular homologue to the transforming protein of simian sarcoma virus

1983 • 116 citations

Mapping of the human gene for epidermal growth factor receptor (EGFR) on the p13→q22 region of chromosome 7

1983 • 112 citations

Genetic analysis of epidermal growth factor action: assignment of human epidermal growth factor receptor gene to chromosome 7.

1980 • 103 citations

Stem cell studies of human malignant brain tumors

1983 • 80 citations

Interferon Inhibits the Establishment of Competence in G ₀ /S-phase Transition

1986 • 75 citations

Amplified, overexpressed and rearranged epidermal growth factor receptor gene in a human astrocytoma cell line

1985 • 75 citations

Oncogenes

1985 • 28 citations

Autocrine regulation of growth: II. Glucocorticoids inhibit transcription of c-sis oncogene-specific RNA transcripts

1984 • 24 citations

Epidermal growth factor receptors in the human glioblastoma cell line SF268 differ from those in epidermoid carcinoma cell line A431

1985 • 12 citations