Immunotherapy of the Nonobese Diabetic Mouse: Treatment with an Antibody to T-Helper Lymphocytes

HLA-DQβ gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

1987 • 2,045 citations

Type I Diabetes Mellitus

1986 • 1,615 citations

Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to the human Leu-3/T4 molecule.

1983 • 1,307 citations

Breeding of a Non-Obese, Diabetic Strain of Mice

1980 • 1,255 citations

Characterization of the Murine Antigenic Determinant, Designated L3T4a, Recognized by Monoclonal Antibody GK 1.5: Expression of L3T4a by Functional T Cell Clones Appears to Correlate Primarily with Class II MHC Antigen‐Reactivity

1983 • 1,040 citations

Successful treatment of autoimmunity in NZB/NZW F1 mice with monoclonal antibody to L3T4.

1985 • 466 citations

The NOD Mouse: Recessive Diabetogenic Gene in the Major Histocompatibility Complex

1986 • 424 citations

The first external domain of the nonobese diabetic mouse class II I-A beta chain is unique.

1987 • 402 citations

Prevention of type II collagen-induced arthritis by in vivo treatment with anti-L3T4.

1985 • 372 citations

The pancreatic islets in diabetes

1981 • 349 citations

Reversal of Experimental Allergic Encephalomyelitis with Monoclonal Antibody to a T-Cell Subset Marker

1985 • 328 citations

Induction of tolerance by monoclonal antibody therapy

1986 • 307 citations

Three Recessive Loci Required for Insulin-Dependent Diabetes in Nonobese Diabetic Mice

1987 • 293 citations

Immunology of Insulin-Dependent Diabetes Mellitus

1985 • 240 citations

Predominance of T lymphocytes in pancreatic islets and spleen of pre-diabetic non-obese diabetic (NOD) mice: a longitudinal study.

1985 • 237 citations

Genetic control of diabetes and insulitis in the nonobese diabetic (NOD) mouse.

1987 • 222 citations

Preventive Effect of Monoclonal Anti-L3T4 Antibody on Development of Diabetes in NOD Mice

1987 • 216 citations

Reversal of advanced murine lupus in NZB/NZW F1 mice by treatment with monoclonal antibody to L3T4.

1987 • 211 citations

Immunologic Aspects of the Nonobese Diabetic (NOD) Mouse: Abnormalities of Cellular Immunity

1983 • 199 citations

CYCLOSPORIN PREVENTS DIABETES IN BB WISTAR RATS

1983 • 183 citations

Islet Allograft Survival After a Single Course of Treatment of Recipient with Antibody to L3T4

1987 • 179 citations

Induction of immune tolerance by administration of monoclonal antibody to L3T4.

1986 • 127 citations

Inhibition of humoral immunity in vivo by monoclonal antibody to L3T4: studies with soluble antigens in intact mice.

1985 • 116 citations

Long-term humoral unresponsiveness in vivo, induced by treatment with monoclonal antibody against L3T4.

1986 • 115 citations

Autoimmune Diabetes in NOD Mouse Is L3T4 T-Lymphocyte Dependent

1987 • 115 citations

Prevention of diabetes mellitus in the BB/W rat with Cyclosporin-A.

1984 • 76 citations

Non-obese-diabetic mice: immune mechanisms of pancreatic ?-cell destruction

1984 • 76 citations

Monoclonal antibodies against mycobacterial antigens

1985 • 31 citations

Immunological aspect of non-obese diabetic mice: immune islet cell-killing mechanism and cell-mediated immunity

1984 • 28 citations