Molecular determinants of glioma cell migration and invasion

Glioma Invasion in the Central Nervous System

1996 • 574 citations

Frequent Co‐Alterations of TP53, p16/CDKN2A, p14^ARF, PTEN Tumor Suppressor Genes in Human Glioma Cell Lines.

1999 • 539 citations

Glioblastoma expression of vitronectin and the alpha v beta 3 integrin. Adhesion mechanism for transformed glial cells.

1991 • 420 citations

Inhibition of invasion and induction of apoptotic cell death of cancer cell lines by overexpression of TIMP-3

1999 • 285 citations

Protooncogene bcl-2 gene transfer abrogates Fas/APO-1 antibody-mediated apoptosis of human malignant glioma cells and confers resistance to chemotherapeutic drugs and therapeutic irradiation.

1995 • 258 citations

PTEN Gene and Integrin Signaling in Cancer

1999 • 186 citations

Matrix metalloproteinase-2 activation modulates glioma cell migration

1997 • 186 citations

Predicting chemoresistance in human malignant glioma cells: The role of molecular genetic analyses

1998 • 171 citations

Vitronectin, a glioma-derived extracellular matrix protein, protects tumor cells from apoptotic death.

1999 • 167 citations

p53 Down-regulates Human Matrix Metalloproteinase-1 (Collagenase-1) Gene Expression

1999 • 144 citations

Cerebral microenvironment influences expression of the vitronectin gene in astrocytic tumors

1995 • 141 citations

Effect of synthetic matrix-metalloproteinase inhibitors on invasive capacity and proliferation of human malignant gliomasIn vitro

1999 • 140 citations

Transforming Growth Factors β1 (TGF-β1) and TGF-β2 Promote Glioma Cell Migration via Up-Regulation of αVβ3 Integrin Expression

2000 • 131 citations

The role of integrins in the malignant phenotype of gliomas

1999 • 123 citations

PTEN gene transfer in human malignant glioma: sensitization to irradiation and CD95L-induced apoptosis

1999 • 112 citations

Diffuse brain invasion of glioma cells requires beta 1 integrins.

1996 • 104 citations

BCL‐2 promotes migration and invasiveness of human glioma cells

1998 • 101 citations

Adenovirus-mediated delivery of antisense gene to urokinase-type plasminogen activator receptor suppresses glioma invasion and tumor growth.

1999 • 97 citations

Growth and migration markers of rat C6 glioma cells identified by serial analysis of gene expression

2000 • 95 citations

Phase I and Pharmacologic Study of the Specific Matrix Metalloproteinase Inhibitor BAY 12-9566 on a Protracted Oral Daily Dosing Schedule in Patients With Solid Malignancies

2000 • 85 citations

Hypericin-induced apoptosis of human malignant glioma cells is light-dependent, independent of bcl-2 expression, and does not require wild-type p53

1997 • 68 citations

ECM-mediated glioma cell invasion

1998 • 65 citations

BAG-1 accelerates cell motility of human gastric cancer cells

1999 • 52 citations

Accumulation of Mutant p53V143A Modulates the Growth, Clonogenicity, and Radiochemosensitivity of Malignant Glioma Cells Independent of Endogenous p53 Status

1999 • 32 citations