Suppression of experimental autoimmune encephalomyelitis in Lewis rats by antibodies against CD2

Adhesion receptors of the immune system

1990 • 6,585 citations

Prevention of experimental autoimmune encephalomyelitis by antibodies against α4βl integrin

1992 • 1,711 citations

An alternative pathway of T-cell activation: A functional role for the 50 kd T11 sheep erythrocyte receptor protein

1984 • 1,132 citations

Limited heterogeneity of T cell receptors from lymphocytes mediating autoimmune encephalomyelitis allows specific immune intervention

1988 • 940 citations

Lymphocyte interactions with endothelial cells

1992 • 689 citations

Immunization with a synthetic T-cell receptor V-region peptide protects against experimental autoimmune encephalomyelitis

1989 • 588 citations

Restricted use of T cell receptor V genes in murine autoimmune encephalomyelitis raises possibilities for antibody therapy

1988 • 555 citations

Role of Lymphocyte Adhesion Receptors in Transient Interactions and Cell Locomotion

1991 • 532 citations

Suppression of experimental allergic encephalomyelitis in Lewis rats after elimination of macrophages.

1990 • 511 citations

A monoclonal antibody to a constant determinant of the rat T cell antigen receptor that induces T cell activation. Differential reactivity with subsets of immature and mature T lymphocytes.

1989 • 455 citations

Authentic T helper CD4 (W3/25) antigen on rat peritoneal macrophages.

1985 • 353 citations

Reversal of Experimental Allergic Encephalomyelitis with Monoclonal Antibody to a T-Cell Subset Marker

1985 • 328 citations

Both rat and mouse T cell receptors specific for the encephalitogenic determinant of myelin basic protein use similar V alpha and V beta chain genes even though the major histocompatibility complex and encephalitogenic determinants being recognized are different.

1989 • 321 citations

Alternative pathway activation of T cells by binding of CD2 to its cell-surface ligand

1987 • 251 citations

Correlation between segmental flexibility and effector function of antibodies

1984 • 235 citations

Experimental allergic encephalomyelitis: successful treatment in vivo with a monoclonal antibody that recognizes T helper cells.

1984 • 222 citations

Effects of in vivo administration of anti-CD3 monoclonal antibody on T cell function in mice. II. In vivo activation of T cells.

1989 • 198 citations

Identification and functional characterization of two distinct epitopes on the human T cell surface protein Tp50.

1983 • 171 citations

Prevention and treatment of murine experimental allergic encephalomyelitis with T cell receptor V beta-specific antibodies.

1990 • 164 citations

Suppression of human T-cell mitogenesis and E-rosette formation by the monoclonal antibody OKT11A.

1981 • 151 citations

Diversity in fine specificity and T cell receptor usage of the human CD4+ cytotoxic T cell response specific for the immunodominant myelin basic protein peptide 87-106.

1992 • 148 citations

Myelin basic protein-specific T lymphocyte repertoire in multiple sclerosis. Complexity of the response and dominance of nested epitopes due to recruitment of multiple T cell clones.

1993 • 145 citations

Is the E receptor on human T lymphocytes a "negative signal receptor"?

1982 • 137 citations

Multiple sclerosis: a pivotal role for the T cell in lesion development

1991 • 118 citations

[31] Myelin basic proteins

1974 • 111 citations

Anti-CD2 receptor and anti-CD2 ligand (CD48) antibodies synergize to prolong allograft survival.

1994 • 94 citations

Anti-CD2 antibodies induce T cell unresponsiveness in vivo.

1991 • 90 citations

Experimental autoimmune encephalomyelitis as a model of immune-mediated CNS disease

1993 • 82 citations

Diversity of T cell receptor α and β chain genes expressed by human T cells specific for similar myelin basic protein peptide/major histocompatibility complexes

1992 • 82 citations

Prevention and therapy of experimental autoimmune neuritis by an antibody against T cell receptors-alpha/beta.

1992 • 75 citations

Selective localisation of neuro-specific T lymphocytes in the central nervous system

1992 • 70 citations

Activation of rat T lymphocytes by anti-CD2 monoclonal antibodies.

1988 • 67 citations

Combined anti-CD2 and anti-CD3 receptor monoclonal antibodies induce donor-specific tolerance in a cardiac transplant model.

1993 • 57 citations

T cell adhesion, avidity regulation and signaling: a molecular analysis of CD2

1993 • 56 citations

Relative contribution of CD2 and LFA-1 to murine T and natural killer cell functions.

1990 • 56 citations

Activation of T Lymphocytes via Monoclonal Antibodies against Rat Cell Surface Antigens with Particular Reference to CD2 Antigen

1989 • 56 citations

Antigen‐specific T cell unresponsiveness in cloned helper T cells mediated via the CD2 or CD3/Ti receptor pathways

1987 • 38 citations

Induction of negative signal through CD2 during antigen-specific T cell activation.

1991 • 34 citations

Diverse T cell receptor β chain usage by rat encephalitogenic T cells reactive to residues 68‐88 of myelin basic protein

1993 • 33 citations

ANTI-CD2 MONOCLONAL ANTIBODIES ALTER CELL-MEDIATED IMMUNITY IN VIVO

1991 • 33 citations

ANTI-CD2 AND ANTI-CD3 MONOCLONAL ANTIBODIES SYNERGIZE TO PROLONG ALLOGRAFT SURVIVAL WITH DECREASED SIDE EFFECTS

1993 • 31 citations

A potential immunosuppressive effect of anti-lymphocyte function-associated antigen-1 monoclonal antibody on islet transplantation.

1994 • 29 citations

T cell vaccination does not induce resistance to experimental autoimmune neuritis

1991 • 26 citations

Successful prevention and treatment of autoimmune encephalomyelitis by short-term administration of anti-T-cell receptor alpha beta antibody.

1994 • 23 citations

Anti-CD2 monoclonal antibodies prevent spontaneous and adoptive transfer of diabetes in the BB/Wor rat.

1992 • 21 citations

Maturation of CD4⁻8⁻α/β TCR⁺T cells induced by CD2-stimulation in vivo and in vitro

1992 • 11 citations

The Ups and Downs of EAE

1993 • 9 citations

PROLONGATION OF RAT PANCREATIC ISLET ALLOGRAFT SURVIVAL BY ANTI-CD2 MONOCLONAL ANTIBODY TREATMENT

1992 • 3 citations

Treatment of clinical experimental allergic encephalomyelitis in the rat using fragments and combinations of monoclonal antibodies

1988 • 3 citations

Characterization of inhibitory effect of an anti-murine CD2 monoclonal antibody on the proliferation of T cell clones

1991 • 3 citations

The T-Cell Antigen Receptor and CD2 in Rat T-Cell Activation and Ontogeny

1989 • 2 citations