Activation of rat T lymphocytes by anti-CD2 monoclonal antibodies.

[1] Preparation of monoclonal antibodies: Strategies and procedures

1981 • 1,787 citations

An alternative pathway of T-cell activation: A functional role for the 50 kd T11 sheep erythrocyte receptor protein

1984 • 1,132 citations

Molecular cloning of the CD2 antigen, the T-cell erythrocyte receptor, by a rapid immunoselection procedure.

1987 • 949 citations

Two subsets of rat T lymphocytes defined with monoclonal antibodies

1980 • 678 citations

The kinetics of antibody binding to membrane antigens in solution and at the cell surface

1980 • 568 citations

Antigens of activated rat T lymphocytes including a molecule of 50,000 Mr detected only on CD4 positive T blasts

1987 • 453 citations

Two antigen-independent adhesion pathways used by human cytotoxic T-cell clones

1986 • 437 citations

Identification of a human T lymphocyte surface protein associated with the E-rosette receptor.

1981 • 419 citations

The localization of populations of lymphocytes defined by monoclonal antibodies in rat lymphoid tissues.

1981 • 389 citations

Authentic T helper CD4 (W3/25) antigen on rat peritoneal macrophages.

1985 • 353 citations

MRC OX‐19: A monoclonal antibody that labels rat T lymphocytes and augments in vitro proliferative responses

1984 • 305 citations

Molecular and antigenic heterogeneity of the rat leukocyte‐common antigen from thymocytes and T and B lymphocytes

1985 • 286 citations

Human T cell activation. II. A new activation pathway used by a major T cell population via a disulfide-bonded dimer of a 44 kilodalton polypeptide (9.3 antigen).

1985 • 285 citations

A human T lymphocyte differentiation marker defined by monoclonal antibodies that block E-rosette formation.

1981 • 281 citations

Purified lymphocyte function-associated antigen 3 binds to CD2 and mediates T lymphocyte adhesion.

1987 • 259 citations

Thy-1 functions as a signal transduction molecule in T lymphocytes and transfected B lymphocytes

1986 • 188 citations

Identification and functional characterization of two distinct epitopes on the human T cell surface protein Tp50.

1983 • 171 citations

Suppression of human T-cell mitogenesis and E-rosette formation by the monoclonal antibody OKT11A.

1981 • 151 citations

T cell activation via CD2 [T, gp50] molecules: accessory cells are required to trigger T cell activation via CD2-D66 plus CD2-9.6/T11(1) epitopes.

1985 • 150 citations

Sialophorin, a surface sialoglycoprotein defective in the Wiskott-Aldrich syndrome, is involved in human T lymphocyte proliferation.

1987 • 145 citations

TAP, a novel T cell-activating protein involved in the stimulation of MHC-restricted T lymphocytes.

1986 • 144 citations

Similarities in sequences and cellular expression between rat CD2 and CD4 antigens.

1987 • 143 citations

Is the E receptor on human T lymphocytes a "negative signal receptor"?

1982 • 137 citations

Analysis of lymphopoietic stem cells with a monoclonal antibody to the rat transferrin receptor.

1985 • 121 citations

Molecular cloning of the human T-lymphocyte surface CD2 (T11) antigen.

1986 • 121 citations

The cell surface molecule recognized by the erythrocyte receptor of T lymphocytes. Identification and partial characterization using a monoclonal antibody.

1985 • 105 citations

T cell activation via CD2 [T, gp50]: the role of accessory cells in activating resting T cells via CD2.

1986 • 105 citations

T cell stimulation via the erythrocyte receptor. Synergism between monoclonal antibodies and phorbol myristate acetate without changes of free cytoplasmic Ca++ levels.

1986 • 81 citations

The murine homologue of the T lymphocyte CD2 antigen: molecular cloning, chromosome assignment and cell surface expression

1987 • 68 citations

Purified lymphocyte function‐associated antigen‐3 and T11 target structure are active in CD2‐mediated T cell stimulation

1987 • 60 citations

Inositol trisphosphate is generated by a rat natural killer cell tumor in response to target cells or to crosslinked monoclonal antibody OX-34: possible signaling role for the OX-34 determinant during activation by target cells.

1987 • 50 citations

Functional properties of the 50 kd protein associated with the E-receptor on human T lymphocytes: suppression of IL 2 production by anti-p50 monoclonal antibodies.

1985 • 40 citations

Quantitative studies of natural immunity to solid tumours in rats. Persistence of natural immunity throughout reproductive life, and absence of suppressor cells in infant rats.

1980 • 40 citations

Semi-automated limit-dilution assay and clonal expansion of all T-cell precursors of cytotoxic lymphocytes

1982 • 38 citations