Lymphocyte interactions with endothelial cells

Adhesion receptors of the immune system

1990 • 6,585 citations

CD44 is the principal cell surface receptor for hyaluronate

1990 • 2,433 citations

Leukocytes roll on a selectin at physiologic flow rates: Distinction from and prerequisite for adhesion through integrins

1991 • 2,195 citations

Endothelial Leukocyte Adhesion Molecule 1: an Inducible Receptor for Neutrophils Related to Complement Regulatory Proteins and Lectins

1989 • 2,045 citations

VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/Fibronectin binding site

1990 • 1,836 citations

A cell-surface molecule involved in organ-specific homing of lymphocytes

1983 • 1,515 citations

Cytokines and endothelial cell biology

1990 • 1,275 citations

Lymphocyte function-associated antigen-1 (LFA-1) interaction with intercellular adhesion molecule-1 (ICAM-1) is one of at least three mechanisms for lymphocyte adhesion to cultured endothelial cells.

1988 • 988 citations

PECAM-1 (CD31) Cloning and Relation to Adhesion Molecules of the Immunoglobulin Gene Superfamily

1990 • 948 citations

Leukocyte adhesion to endothelium in inflammation

1990 • 882 citations

ELAM-1 is an adhesion molecule for skin-homing T cells

1991 • 843 citations

Identification and characterization of the T lymphocyte adhesion receptor for an alternative cell attachment domain (CS-1) in plasma fibronectin.

1989 • 807 citations

Naive and memory T cells show distinct pathways of lymphocyte recirculation.

1990 • 792 citations

Adhesion molecules controlling lymphocyte migration

1989 • 654 citations

The neutrophil selectin LECAM-1 presents carbohydrate ligands to the vascular selectins ELAM-1 and GMP-140

1991 • 592 citations

CD44 — A molecule involved in leukocyte adherence and T-cell activation

1989 • 559 citations

Lymphocyte recognition of high endothelium: antibodies to distinct epitopes of an 85-95-kD glycoprotein antigen differentially inhibit lymphocyte binding to lymph node, mucosal, or synovial endothelial cells.

1987 • 554 citations

Role of Lymphocyte Adhesion Receptors in Transient Interactions and Cell Locomotion

1991 • 532 citations

Cytokines as communication signals between leukocytes and endothelial cells

1989 • 528 citations

Characterization of ICAM-2 and evidence for a third counter-receptor for LFA-1.

1991 • 510 citations

Enhancement of LFA-1-mediated cell adhesion by triggering through CD2 or CD3 on T lymphocytes

1989 • 482 citations

Ligands “activate” integrin αIIbβ3 (platelet GPIIb-IIIa)

1991 • 481 citations

Lectin-like cell adhesion molecule 1 mediates leukocyte rolling in mesenteric venules in vivo

1991 • 473 citations

Leukocyte-endothelial cell recognition: evidence of a common molecular mechanism shared by neutrophils, lymphocytes, and other leukocytes.

1987 • 417 citations

Leukocyte adhesion molecule-1 (LAM-1, L-selectin) interacts with an inducible endothelial cell ligand to support leukocyte adhesion.

1991 • 406 citations

Activation-independent binding of human memory T cells to adhesion molecule ELAM-1

1991 • 379 citations

The hyaluronate receptor is a member of the CD44 (H-CAM) family of cell surface glycoproteins [published erratum appears in J Cell Biol 1991 Feb;112(3):following 513]

1990 • 368 citations

A human endothelial cell-restricted, externally disposed plasmalemmal protein enriched in intercellular junctions.

1989 • 365 citations

Endothelial-leukocyte adhesion molecule 1 stimulates the adhesive activity of leukocyte integrin CR3 (CD11b/CD18, Mac-1, alpha m beta 2) on human neutrophils.

1991 • 347 citations

Four molecular pathways of T cell adhesion to endothelial cells: roles of LFA-1, VCAM-1, and ELAM-1 and changes in pathway hierarchy under different activation conditions.

1991 • 343 citations

Carbohydrate ligands of the LEC cell adhesion molecules

1990 • 338 citations

Roles of Adhesion Molecules in T‐Cell Recognition: Fundamental Similarities between Four Integrins on Resting Human T Cells (LFA‐1, VLA‐4, VLA‐5, VLA‐6) in Expression, Binding, and Costimulation

1990 • 322 citations

Identification of a carbohydrate-based endothelial ligand for a lymphocyte homing receptor.

1991 • 308 citations

The human peripheral lymph node vascular addressin is a ligand for LECAM-1, the peripheral lymph node homing receptor.

1991 • 307 citations

Vascular and nonvascular expression of INCAM-110. A target for mononuclear leukocyte adhesion in normal and inflamed human tissues.

1991 • 306 citations

Immune and inflammatory processes in cutaneous tissues. Mechanisms and speculations.

1990 • 303 citations

Evidence for an accessory role of LFA-1 in lymphocyte-high endothelium interaction during homing.

1988 • 302 citations

Neutrophil influx into an inflammatory site inhibited by a soluble homing receptor–IgG chimaera

1991 • 293 citations

Analysis of T cell stimulation by superantigen plus major histocompatibility complex class II molecules or by CD3 monoclonal antibody: costimulation by purified adhesion ligands VCAM-1, ICAM-1, but not ELAM-1.

1991 • 293 citations

The Regulation of Lymphocyte Traffic

1986 • 285 citations

T-cell memory: the connection between function, phenotype and migration pathways

1991 • 271 citations

Differential expression of homing-associated adhesion molecules by T cell subsets in man.

1990 • 270 citations

Expression of the human leukocyte adhesion molecule, LAM1. Identity with the TQ1 and Leu-8 differentiation antigens.

1990 • 263 citations

The synergy between naive and memory T cells during activation

1991 • 247 citations

The preferential accumulation of helper‐inducer T lymphocytes in inflammatory lesions: evidence for regulation by selective endothelial and homotypic adhesion

1988 • 230 citations

Lymphocyte Homing

1989 • 227 citations

Predominance of ?memory? T cells (CD4+, CDw29+) over ?naive? T cells (CD4+, CD45R+) in both normal and diseased human skin

1989 • 218 citations

Human T lymphocyte adhesion to endothelial cells and transendothelial migration. Alteration of receptor use relates to the activation status of both the T cell and the endothelial cell.

1990 • 199 citations

T cells bind to cytokine-activated endothelial cells via a novel, inducible sialoglycoprotein and endothelial leukocyte adhesion molecule-1.

1990 • 196 citations

Mechanisms and regulation of lymphocyte migration

1989 • 191 citations

Specific Cell-Adhesion Mechanisms Determining Migration Pathways of Recirculating Lymphocytes

1987 • 181 citations

Lymphocyte emigration from high endothelial venules in rat lymph nodes.

1976 • 180 citations

An alternative leukocyte homotypic adhesion mechanism, LFA-1/ICAM-1-independent, triggered through the human VLA-4 integrin.

1990 • 180 citations

Warner-Lambert/Parke-Davis Award lecture. Cellular and molecular mechanisms that direct leukocyte traffic.

1990 • 170 citations

Role of endothelial leukocyte adhesion molecule-1 and platelet-activating factor in neutrophil adherence to IL-1-prestimulated endothelial cells. Endothelial leukocyte adhesion molecule-1-mediated CD18 activation.

1991 • 168 citations

Biased accumulation of T lymphocytes with "memory"-type CD45 leukocyte common antigen gene expression on the epithelial surface of the human lung.

1990 • 159 citations

Heterogeneous distribution and transmembrane signaling properties of lymphocyte function-associated antigen (LFA-1) in human lymphocyte subsets.

1989 • 158 citations

Endothelial cells augment T cell interleukin 2 production by a contact-dependent mechanism involving CD2/LFA-3 interaction.

1990 • 143 citations

A monoclonal antibody to VLA-4 alpha-chain (CDw49d) induces homotypic lymphocyte aggregation.

1990 • 142 citations

Evidence for differential expression of CD45 isoforms by precursors for memory-dependent and independent cytotoxic responses: human CD8 memory CTLp selectively express CD45R0 (UCHL1)

1989 • 138 citations

Role of CD11/CD18 in adhesion and transendothelial migration of T cells. Analysis utilizing CD18-deficient T cell clones.

1991 • 136 citations

Phenotypic analysis of lamina propria lymphocytes. Predominance of helper-inducer and cytolytic T-cell phenotypes and deficiency of suppressor-inducer phenotypes in Crohn's disease and control patients.

1986 • 135 citations

T cell receptor-dependent, antigen-specific stimulation of a murine T cell clone induces a transient, VLA protein-mediated binding to extracellular matrix.

1991 • 125 citations

Phenotypic analysis of lamina propria lymphocytes

1986 • 117 citations

Effect of a new monoclonal antibody, TA-2, that inhibits lymphocyte adherence to cytokine stimulated endothelium in the rat.

1991 • 116 citations

Lymphocyte recognition of lymph node high endothelium. VII. Cell surface proteins involved in adhesion defined by monoclonal anti-HEBFLN (A.11) antibody.

1985 • 106 citations

Dynamics of Lymphocyte-Endothelial Interactions in Vivo

1986 • 100 citations

A monoclonal anti-HEBFPP antibody with specificity for lymphocyte surface molecules mediating adhesion to Peyer's patch high endothelium of the rat.

1986 • 99 citations

Integrin Molecules Involved in Lymphocyte Homing to Peyer's Patches

1989 • 98 citations

Ability of human T lymphocytes to adhere to vascular endothelial cells and to augment endothelial permeability to macromolecules is linked to their state of post-thymic maturation.

1990 • 72 citations

Immunological memory in T cells

1991 • 53 citations

Prevention of lymphadenopathy in MRL-lpr/lpr mice by blocking peripheral lymph node homing with Mel-14 in vivo.

1988 • 43 citations

Use of synthetic peptides to probe lymphocyte- high endothelial cell interactions. Lymphocytes recognize a ligand on the endothelial surface which contains the CS1 adhesion motif

1990 • 41 citations

Lymphocyte surface marker expression in rheumatic diseases: evidence for prior activation of lymphocytes in vivo.

1990 • 31 citations

Leukocyte-endothelial cell interaction and the control of leukocyte migration into inflamed synovium

1989 • 27 citations

Separation and characterization of human T lymphocytes with varying adhesiveness for endothelial cells

1988 • 27 citations

Increased lymphocyte adherence to human arterial endothelial cell monolayers in the context of allorecognition.

1990 • 24 citations

Structure and Function of High Endothelial Postcapillary Venules in Lymphocyte Circulation

1990 • 24 citations