Analysis of Clonotype Distribution and Persistence for an Influenza Virus-Specific CD8+ T Cell Response

Counting Antigen-Specific CD8 T Cells: A Reevaluation of Bystander Activation during Viral Infection

1998 • 1,996 citations

An αβ T Cell Receptor Structure at 2.5 Å and Its Orientation in the TCR-MHC Complex

1996 • 1,282 citations

Fundamental Immunology

1999 • 1,011 citations

A Direct Estimate of the Human αβ T Cell Receptor Diversity

1999 • 893 citations

Virus-Specific CD8+ T Cells in Primary and Secondary Influenza Pneumonia

1998 • 685 citations

The sizes of the CDR3 hypervariable regions of the murine T-cell receptor beta chains vary as a function of the recombined germ-line segments.

1993 • 664 citations

Complete primary structure of a heterodimeric T-cell receptor deduced from cDNA sequences

1984 • 652 citations

Major expansion of CD8+ T cells with a predominant Vβ usage during the primary immune response to HIV

1994 • 611 citations

Coordinate Regulation of Complex T Cell Populations Responding to Bacterial Infection

1998 • 535 citations

Mapping T-cell receptor–peptide contacts by variant peptide immunization of single-chain transgenics

1992 • 531 citations

Virus-specific CD8+ T-cell memory determined by clonal burst size

1994 • 525 citations

Antigen-Specific Development of Primary and Memory T Cells in Vivo

1995 • 444 citations

Mouse T cell antigen receptor: Structure and organization of constant and joining gene segments encoding the β polypeptide

1984 • 407 citations

Future influenza vaccines and the use of genetic recombinants.

1969 • 386 citations

Genomic organization and sequence of T-cell receptor β-chain constant- and joining-region genes

1984 • 377 citations

Roles of alphabeta and gammadelta T Cell Subsets in Viral Immunity

1992 • 350 citations

Cellular events in the lymph node and lung of mice with influenza. Consequences of depleting CD4+ T cells.

1990 • 340 citations

Measuring the diaspora for virus-specific CD8⁺T cells

2001 • 288 citations

Accessing Complexity: The Dynamics of Virus-Specific T Cell Responses

2000 • 283 citations

A Previously Unrecognized H-2D^b-Restricted Peptide Prominent in the Primary Influenza A Virus-Specific CD8⁺T-Cell Response Is Much Less Apparent following Secondary Challenge

2000 • 260 citations

Conserved T Cell Receptor Repertoire in Primary and Memory CD8 T Cell Responses to an Acute Viral Infection

1998 • 229 citations

Evolution of a Complex T Cell Receptor Repertoire during Primary and Recall Bacterial Infection

1998 • 202 citations

Public and private V beta T cell receptor repertoires against hen egg white lysozyme (HEL) in nontransgenic versus HEL transgenic mice.

1994 • 194 citations

Individual Variations in the Murine T Cell Response to a Specific Peptide Reflect Variability in Naive Repertoires

1998 • 192 citations

Single-Cell PCR Analysis of TCR Repertoires Selected by Antigen In Vivo: A High Magnitude CD8 Response Is Comprised of Very Few Clones

1996 • 174 citations

Evolution of Antigen-specific T Cell Receptors In Vivo: Preimmune and Antigen-driven Selection of Preferred Complementarity-determining Region 3 (CDR3) Motifs

1999 • 151 citations

Evolution of the T Cell Repertoire During Primary, Memory, and Recall Responses to Viral Infection

2000 • 150 citations

In vivoproliferation of naïve and memory influenza-specific CD8⁺T cells

1999 • 146 citations

Stability and Diversity of T Cell Receptor Repertoire Usage during Lymphocytic Choriomeningitis Virus Infection of Mice

1998 • 141 citations

Mouse T-cell receptor variable gene segment families

1995 • 138 citations

Recruitment and proliferation of CD8+ T cells in respiratory virus infections.

1995 • 130 citations

Selective Activation and Expansion of High-Affinity CD4+ T Cells in Resistant Mice upon Infection with Leishmania major

2000 • 130 citations

Profound Protection against Respiratory Challenge with a Lethal H7N7 Influenza A Virus by Increasing the Magnitude of CD8⁺T-Cell Memory

2000 • 121 citations

Virus-specific antigen presentation by different subsets of cells from lung and mediastinal lymph node tissues of influenza virus-infected mice

1995 • 118 citations

Changing Patterns of Dominant TCR Usage with Maturation of an EBV-Specific Cytotoxic T Cell Response

2000 • 117 citations

Identification of conserved T cell receptor CDR3 residues contacting known exposed peptide side chains from a major histocompatibility complex class I‐bound determinant

1993 • 116 citations

Influenza virus RNA in the lung and lymphoid tissue of immunologically intact and CD4-depleted mice

1991 • 115 citations

Contemporary Analysis of MHC-Related Immunodominance Hierarchies in the CD8+ T Cell Response to Influenza A Viruses

2000 • 111 citations

A γ-herpesvirus sneaks through a CD8⁺T cell response primed to a lytic-phase epitope

1999 • 111 citations

Influenza Viruses, Cell Enzymes, and Pathogenicity

1995 • 102 citations

Preferential usage of V_α4 and V_β10 T cell receptor genes by lymphocytic choriomeningitis virus glycoprotein‐specific H‐2D^b‐restricted cytotoxic T cells

1990 • 89 citations

Characterization of diverse primary herpes simplex virus type 1 gB-specific cytotoxic T-cell response showing a preferential V beta bias

1995 • 87 citations

A Class I MHC-Restricted Recall Response to a Viral Peptide Is Highly Polyclonal Despite Stringent CDR3 Selection: Implications for Establishing Memory T Cell Repertoires in “Real-World” Conditions

1998 • 87 citations

Inflammatory infiltration of the upper airway epithelium during Sendai virus infection: involvement of epithelial dendritic cells

1997 • 86 citations

T-Cell Antigen Receptors

1990 • 85 citations

T Cell Receptor (Tcr)-Mediated Repertoire Selection and Loss of Tcr Vβ Diversity during the Initiation of a Cd4+ T Cell Response in Vivo

2000 • 77 citations

Enumeration of Antigen-Presenting Cells in Mice Infected with Sendai Virus

1999 • 70 citations

T cell receptor variable gene usage in a specific cytotoxic T cell response. Primary structure of the antigen-MHC receptor of four hapten-specific cytotoxic T cell clones.

1987 • 68 citations

Intestinal and Splenic T Cell Responses to EntericListeria monocytogenesInfection: Distinct Repertoires of Responding CD8 T Lymphocytes

2001 • 67 citations

Restricted V-segment usage in T-cell receptors from cytotoxic T lymphocytes specific for a major epitope of lymphocytic choriomeningitis virus

1990 • 63 citations

Virus-specific memory T cells are Pgp-1+ and can be selectively activated with phorbol ester and calcium lonophore

1988 • 60 citations

Concurrent Naive and Memory CD8+ T Cell Responses to an Influenza A Virus

2001 • 60 citations

Junctional Biases in the Naive TCR Repertoire Control the CTL Response to an Immunodominant Determinant of HSV-1

2000 • 55 citations

On defining the rules for interactions between the T cell receptor and its ligand: A critical role for a specific amino acid residue of the T cell receptor β chain

1998 • 49 citations

The TCR Repertoire of an Immunodominant CD8+ T Lymphocyte Population

2001 • 49 citations

Location and character of the cellular enzyme that cleaves the hemagglutinin of a virulent avian influenza virus

1992 • 47 citations

Persistent HIV-1-Specific CTL Clonal Expansion Despite High Viral Burden Post In Utero HIV-1 Infection

1999 • 40 citations

Persistence of Human Immunodeficiency Virus Type 1-Specific Cytotoxic T-Lymphocyte Clones in a Subject with Rapid Disease Progression

2001 • 32 citations

Memory TCR repertoires analyzed long-term reflect those selected during the primary response

1996 • 24 citations

Functional mapping of the orientation for TCR recognition of an H2-Kb-restricted ovalbumin peptide suggests that the beta-chain subunit can dominate the determination of peptide side chain specificity.

1997 • 21 citations

Individuality of Ag-Selected and Preimmune TCR Repertoires

2001 • 9 citations