Profound Protection against Respiratory Challenge with a Lethal H7N7 Influenza A Virus by Increasing the Magnitude of CD8⁺T-Cell Memory

Counting Antigen-Specific CD8 T Cells: A Reevaluation of Bystander Activation during Viral Infection

1998 • 1,996 citations

The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides

1986 • 1,723 citations

Human influenza A H5N1 virus related to a highly pathogenic avian influenza virus

1998 • 1,386 citations

Induction of Bystander T Cell Proliferation by Viruses and Type I Interferon in Vivo

1996 • 1,077 citations

IMMUNODOMINANCE IN MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I–RESTRICTED T LYMPHOCYTE RESPONSES

1999 • 923 citations

Turnover of naive- and memory-phenotype T cells.

1994 • 900 citations

Virus-Specific CD8+ T Cells in Primary and Secondary Influenza Pneumonia

1998 • 685 citations

Virus-specific CD8+ T-cell memory determined by clonal burst size

1994 • 525 citations

Heterosubtypic immunity to influenza type A virus in mice. Effector mechanisms and their longevity.

1994 • 400 citations

Future influenza vaccines and the use of genetic recombinants.

1969 • 386 citations

Cellular events in the lymph node and lung of mice with influenza. Consequences of depleting CD4+ T cells.

1990 • 340 citations

A Previously Unrecognized H-2D^b-Restricted Peptide Prominent in the Primary Influenza A Virus-Specific CD8⁺T-Cell Response Is Much Less Apparent following Secondary Challenge

2000 • 260 citations

Resistance to and Recovery from Lethal Influenza Virus Infection in B Lymphocyte–deficient Mice

1997 • 239 citations

Delayed clearance of Sendai virus in mice lacking class I MHC-restricted CD8+ T cells.

1992 • 237 citations

Vaccination with HPV16 peptides of patients with advanced cervical carcinoma: clinical evaluation of a phase I–II trial

1999 • 231 citations

Clearance of an Influenza A Virus by CD4⁺T Cells Is Inefficient in the Absence of B Cells

1998 • 169 citations

In vivoproliferation of naïve and memory influenza-specific CD8⁺T cells

1999 • 146 citations

Protective cellular immunity: cytotoxic T-lymphocyte responses against dominant and recessive epitopes of influenza virus nucleoprotein induced by DNA immunization

1997 • 132 citations

Recruitment and proliferation of CD8+ T cells in respiratory virus infections.

1995 • 130 citations

Treatment of Influenza Virus-Infected SCID Mice with Nonneutralizing Antibodies Specific for the Transmembrane Proteins Matrix 2 and Neuraminidase Reduces the Pulmonary Virus Titer but Fails to Clear the Infection

1999 • 119 citations

Virus-specific antigen presentation by different subsets of cells from lung and mediastinal lymph node tissues of influenza virus-infected mice

1995 • 118 citations

A γ-herpesvirus sneaks through a CD8⁺T cell response primed to a lytic-phase epitope

1999 • 111 citations

DECLINING T-CELL IMMUNITY TO INFLUENZA, 1977-82

1983 • 109 citations

Broadly cross-reactive HIV-specific cytotoxic T-lymphocytes in highly-exposed persistently seronegative donors

1999 • 105 citations

Recombinant modified vaccinia virus Ankara–simian immunodeficiency virusgag polelicits cytotoxic T lymphocytes in rhesus monkeys detected by a major histocompatibility complex class I/peptide tetramer

1998 • 104 citations

Strong Human Immunodeficiency Virus (HIV)-Specific Cytotoxic T-Lymphocyte Activity in Sydney Blood Bank Cohort Patients Infected withnef-Defective HIV Type 1

1999 • 104 citations

Th Cell-Deficient Mice Control Influenza Virus Infection More Effectively Than Th- and B Cell-Deficient Mice: Evidence for a Th-Independent Contribution by B Cells to Virus Clearance

2000 • 96 citations

Recombinant viruses expressing a human malaria antigen can elicit potentially protective immune CD8⁺responses in mice

1998 • 88 citations

Inflammatory infiltration of the upper airway epithelium during Sendai virus infection: involvement of epithelial dendritic cells

1997 • 86 citations

Primary pulmonary cytotoxic T lymphocytes induced by immunization with a vaccinia virus recombinant expressing influenza A virus nucleoprotein peptide do not protect mice against challenge

1994 • 83 citations

Influenza – A Model of an Emerging Virus Disease

1993 • 75 citations

T-Cell Recognition of Human Melanoma Antigens

1993 • 68 citations

Protection against a Lethal Avian Influenza A Virus in a Mammalian System

1999 • 54 citations

Effective Immunization with Live Attenuated Influenza A Virus Can Be Achieved in Early Infancy

1996 • 51 citations

Quantitative studies of the inflammatory process in fatal viral meningoencephalitis.

1973 • 51 citations

Equine H7N7 influenza A viruses are highly pathogenic in mice without adaptation: potential use as an animal model

1991 • 49 citations

Heterotypic Immune Mice Lose Protection against Influenza Virus Infection with Senescence

1993 • 44 citations

Frequencies and regulation of trinitrophenyl-specific cytotoxic T precursor cells: immunization results in release from suppression.

1983 • 38 citations

Efficacy of Influenza Haemagglutinin and Nucleoprotein as Protective Antigens against Influenza Virus Infection in Mice

1988 • 38 citations

Dendritic cells: Therapeutic potentials

1997 • 22 citations

Higher Frequency of a Protein Band in the Cerebrospinal Fluid from Scrapie Mice

1973 • 7 citations