Differential binding to HLA-C of p50-activating and p58-inhibitory natural killer cell receptors

Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons

1991 • 5,267 citations

RASMOL: biomolecular graphics for all

1995 • 2,601 citations

HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C

1998 • 2,114 citations

NK CELL RECEPTORS

1998 • 1,666 citations

Human Diversity in Killer Cell Inhibitory Receptor Genes

1997 • 1,052 citations

HLA-E is a major ligand for the natural killer inhibitory receptor CD94/NKG2A

1998 • 998 citations

Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells

1998 • 892 citations

RECEPTORS FOR HLA CLASS-I MOLECULES IN HUMAN NATURAL KILLER CELLS

1996 • 871 citations

Cloning of Immunoglobulin-Superfamily Members Associated with HLA-C and HLA-B Recognition by Human Natural Killer Cells

1995 • 735 citations

Functionally and Structurally Distinct NK Cell Receptor Repertoires in the Peripheral Blood of Two Human Donors

1997 • 735 citations

Recognition of Human Histocompatibility Leukocyte Antigen (HLA)-E Complexed with HLA Class I Signal Sequence–derived Peptides by CD94/NKG2 Confers Protection from Natural Killer Cell–mediated Lysis

1998 • 706 citations

Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains

1995 • 575 citations

P58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities.

1993 • 537 citations

CD80 (B7-1) Binds Both CD28 and CTLA-4 with a Low Affinity and Very Fast Kinetics

1997 • 525 citations

Antigen and Fc receptor signaling. The awesome power of the immunoreceptor tyrosine-based activation motif (ITAM).

1995 • 463 citations

Existence of both inhibitory (p58) and activatory (p50) receptors for HLA-C molecules in human natural killer cells.

1995 • 446 citations

Human natural killer cell receptors involved in MHC class I recognition are disulfide-linked heterodimers of CD94 and NKG2 subunits.

1996 • 441 citations

Direct Binding and Functional Transfer of NK Cell Inhibitory Receptors Reveal Novel Patterns of HLA-C Allotype Recognition

1998 • 426 citations

HLA-E-bound peptides influence recognition by inhibitory and triggering CD94/NKG2 receptors: preferential response to an HLA-G-derived nonamer

1998 • 366 citations

The natural killer cell receptor specific for HLA-A allotypes: a novel member of the p58/p70 family of inhibitory receptors that is characterized by three immunoglobulin-like domains and is expressed as a 140-kD disulphide-linked dimer.

1996 • 365 citations

A human killer inhibitory receptor specific for HLA-A1,2.

1996 • 347 citations

Protection from lysis by natural killer cells of group 1 and 2 specificity is mediated by residue 80 in human histocompatibility leukocyte antigen C alleles and also occurs with empty major histocompatibility complex molecules.

1996 • 340 citations

Killer cell inhibitory receptors specific for HLA-C and HLA-B identified by direct binding and by functional transfer

1995 • 338 citations

The human leukocyte antigen (HLA)-C-specific "activatory" or "inhibitory" natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions.

1996 • 337 citations

Superantigen-Dependent, Cell-Mediated Cytotoxicity Inhibited by MHC Class I Receptors on T Lymphocytes

1995 • 316 citations

Molecular cloning of NKB1. A natural killer cell receptor for HLA-B allotypes.

1995 • 309 citations

The CD94 and NKG2‐A C‐type lectins covalently assemble to form a natural killer cell inhibitory receptor for HLA class I molecules

1997 • 271 citations

Human killer cell activatory receptors for MHC class I molecules are included in a multimeric complex expressed by natural killer cells.

1997 • 260 citations

A novel surface antigen expressed by a subset of human CD3- CD16+ natural killer cells. Role in cell activation and regulation of cytolytic function.

1990 • 254 citations

NKG2A Complexed with CD94 Defines a Novel Inhibitory Natural Killer Cell Receptor

1997 • 252 citations

A single amino acid in the p58 killer cell inhibitory receptor controls the ability of natural killer cells to discriminate between the two groups of HLA-C allotypes.

1997 • 224 citations

Role of amino acid position 70 in the binding affinity of p50.1 and p58.1 receptors for HLA‐Cw4 molecules

1997 • 216 citations

The Direct Binding of a p58 Killer Cell Inhibitory Receptor to Human Histocompatibility Leukocyte Antigen (HLA)-Cw4 Exhibits Peptide Selectivity

1997 • 208 citations

Specificity of HLA class I antigen recognition by human NK clones: evidence for clonal heterogeneity, protection by self and non-self alleles, and influence of the target cell type.

1993 • 178 citations

Structure of the inhibitory receptor for human natural killer cells resembles haematopoietic receptors

1997 • 168 citations

Alloantigen recognition by two human natural killer cell clones is associated with HLA-C or a closely linked gene.

1992 • 157 citations

Allele-specific peptide ligand motifs of HLA-C molecules.

1993 • 128 citations

Kinetics of Interaction of HLA-C Ligands with Natural Killer Cell Inhibitory Receptors

1998 • 121 citations

Killer cell receptors: keeping pace with MHC class I evolution

1997 • 110 citations

Transduction of cytotoxic signals in natural killer cells: a general model of fine tuning between activatory and inhibitory pathways in lymphocytes

1997 • 107 citations

Signaling through human killer cell activating receptors triggers tyrosine phosphorylation of an associated protein complex

1998 • 96 citations

Enhancement of Class II-Restricted T cell Responses by Costimulatory NK Receptors for Class I MHC Proteins

1996 • 89 citations

Human NK cells: their ligands, receptors and functions

1997 • 89 citations

Direct binding of a soluble natural killer cell inhibitory receptor to a soluble human leukocyte antigen-Cw4 class I major histocompatibility complex molecule.

1996 • 88 citations

The NKB1 and HP-3E4 NK cells receptors are structurally distinct glycoproteins and independently recognize polymorphic HLA-B and HLA-C molecules.

1995 • 82 citations

Nucleotide and amino acid sequence alignment for human killer cell inhibitory receptors (KIR), 1998

1998 • 82 citations

Self and viral peptides can initiate lysis by autologous natural killer cells

1997 • 79 citations

Natural killer activating receptors trigger interferon γ secretion from T cells and natural killer cells

1998 • 67 citations

Molecular basis of HLA-C recognition by p58 natural killer cell inhibitory receptors.

1997 • 43 citations

The natural killer-related receptor for HLA-C expressed on T cells from CD3+ lymphoproliferative disease of granular lymphocytes displays either inhibitory or stimulatory function

1996 • 30 citations