Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Current protocols in molecular biology

1988 • 7,584 citations

Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction

1989 • 3,557 citations

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

1992 • 2,618 citations

In search of the ‘missing self’: MHC molecules and NK cell recognition

1990 • 2,600 citations

The Immunoglobulin Superfamily—Domains for Cell Surface Recognition

1988 • 2,237 citations

Signal transduction by lymphocyte antigen receptors

1994 • 2,145 citations

Current protocols in immunology

1992 • 1,464 citations

MHC class I alloantigen specificity of Ly-49+ IL-2-activated natural killer cells

1992 • 805 citations

P58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities.

1993 • 537 citations

The Bw4 public epitope of HLA-B molecules confers reactivity with natural killer cell clones that express NKB1, a putative HLA receptor.

1995 • 507 citations

The Ly-49 and NKR-P1 Gene Families Encoding Lectin-Like Receptors on Natural Killer Cells: The NK Gene Complex

1993 • 465 citations

HLA-C is the inhibitory ligand that determines dominant resistance to lysis by NK1- and NK2-specific natural killer cells.

1993 • 455 citations

A unique signature identifies a family of zinc‐dependent metallopeptidases

1989 • 453 citations

Human NKR-P1A. A disulfide-linked homodimer of the C-type lectin superfamily expressed by a subset of NK and T lymphocytes.

1994 • 408 citations

Identification of four subsets of human CD3-CD16+ natural killer (NK) cells by the expression of clonally distributed functional surface molecules: correlation between subset assignment of NK clones and ability to mediate specific alloantigen recognition.

1990 • 388 citations

Natural killer (NK) cells are present in mice with severe combined immunodeficiency (scid).

1985 • 362 citations

NKB1: a natural killer cell receptor involved in the recognition of polymorphic HLA-B molecules.

1994 • 343 citations

Peptide Specificity in the Recognition of MHC Class I by Natural Killer Cell Clones

1995 • 308 citations

Molecular cloning, expression, and chromosomal localization of the human earliest lymphocyte activation antigen AIM/CD69, a new member of the C-type animal lectin superfamily of signal-transmitting receptors.

1993 • 280 citations

Gamma ray-induced loss of expression of HLA and glyoxalase I alleles in lymphoblastoid cells.

1980 • 257 citations

Oligosaccharide ligands for NKR-P1 protein activate NK cells and cytotoxicity

1994 • 256 citations

A novel surface antigen expressed by a subset of human CD3- CD16+ natural killer cells. Role in cell activation and regulation of cytolytic function.

1990 • 254 citations

Involvement of HLA class I alleles in natural killer (NK) cell-specific functions: expression of HLA-Cw3 confers selective protection from lysis by alloreactive NK clones displaying a defined specificity (specificity 2).

1992 • 218 citations

Human natural killer cell receptors for HLA-class I molecules. Evidence that the Kp43 (CD94) molecule functions as receptor for HLA-B alleles.

1994 • 193 citations

Evidence of a natural killer (NK) cell repertoire for (allo) antigen recognition: definition of five distinct NK-determined allospecificities in humans.

1992 • 190 citations

Binding of diverse peptides to MHC class I molecules inhibits target cell lysis by activated natural killer cells

1995 • 180 citations

Specificity of HLA class I antigen recognition by human NK clones: evidence for clonal heterogeneity, protection by self and non-self alleles, and influence of the target cell type.

1993 • 178 citations

Ly-49 mediates EL4 lymphoma adhesion to isolated class I major histocompatibility complex molecules.

1994 • 162 citations

A natural killer cell receptor specific for a major histocompatibility complex class I molecule.

1994 • 157 citations

A multigene family on human chromosome 12 encodes natural killer-cell lectins

1993 • 125 citations

Cell surface phenotype of a cloned line of human natural killer cells.

1982 • 124 citations

Efficient cDNA expression vectors for stable and transient expression of HLA-DR in transfected fibroblast and lymphoid cells

1991 • 124 citations

Ly-49A, a receptor for H-2Dd, has a functional carbohydrate recognition domain

1994 • 115 citations

Self class I molecules protect normal cells from lysis mediated by autologous natural killer cells

1994 • 94 citations

Natural killer cell receptors specific for major histocompatibility complex class I molecules.

1995 • 88 citations

Recognition of virus-infected cells by natural killer cell clones is controlled by polymorphic target cell elements.

1993 • 85 citations

The NKB1 and HP-3E4 NK cells receptors are structurally distinct glycoproteins and independently recognize polymorphic HLA-B and HLA-C molecules.

1995 • 82 citations

Multiple natural killer cell‐activating signals are inhibited by major histocompatibility complex class I expression in target cells

1994 • 81 citations

Coexpression of two functionally independent p58 inhibitory receptors in human natural killer cell clones results in the inability to kill all normal allogeneic target cells.

1995 • 65 citations

The human natural killer cell receptor for major histocompatibility complex class I molecules. Surface modulation of p58 molecules and their linkage to CD3 ζ chain, FcϵRI γ chain and the p56^lck kinase

1994 • 50 citations

Organization of human T-cell receptor beta-chain genes: clusters of V beta genes are present on chromosomes 7 and 9.

1993 • 45 citations

Human CD3⁻CD16⁺ natural killer cells express the hGATA‐3 T cell transcription factor and an unrearranged 2.3‐kb TcR δ transcript

1993 • 24 citations

Isolation of Proteins for Microsequence Analysis

1992 • 4 citations