Transmembrane signaling by a chimera of the Escherichia coli aspartate receptor and the human insulin receptor.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

1984 • 2,762 citations

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

1985 • 2,257 citations

The human insulin receptor cDNA: The structural basis for hormone-activated transmembrane signalling

1985 • 1,485 citations

The human LDL receptor: A cysteine-rich protein with multiple Alu sequences in its mRNA

1984 • 1,386 citations

[42] Detection and quantification of phosphotyrosine in proteins

1983 • 1,184 citations

After Insulin Binds

1987 • 687 citations

Plasmid vectors for high-efficiency expression controlled by the promoter of coliphage lambda

1981 • 664 citations

Signal Transduction by the Platelet-Derived Growth Factor Receptor

1989 • 653 citations

Complete primary structure of a heterodimeric T-cell receptor deduced from cDNA sequences

1984 • 652 citations

Phosphorylation activates the insulin receptor tyrosine protein kinase.

1983 • 558 citations

[67] Separation of the inner (cytoplasmic) and outer membranes of gram-negative bacteria

1974 • 320 citations

Identification of a protein methyltransferase as the cheR gene product in the bacterial sensing system.

1977 • 307 citations

Sensory transduction in Escherichia coli: two complementary pathways of information processing that involve methylated proteins.

1977 • 281 citations

Construction and analysis of in vivo activity of E. coll promoter hybrids and promoter mutants that alter the −35 to −10 spacing

1982 • 219 citations

Sensory transducers of E. coli are composed of discrete structural and functional domains

1983 • 212 citations

Separation of Signal Transduction and Adaptation Functions of the Aspartate Receptor in Bacterial Sensing

1983 • 196 citations

Structure of the serine chemoreceptor in Escherichia coli

1983 • 182 citations

Myristyl and palmityl acylation of the insulin receptor.

1987 • 114 citations

Structure of the Trg protein: Homologies with and differences from other sensory transducers of Escherichia coli.

1984 • 109 citations

Relationship of site-specific beta subunit tyrosine autophosphorylation to insulin activation of the insulin receptor (tyrosine) protein kinase activity.

1988 • 103 citations

DEFINITION OF ADDITIONAL FLAGELLAR GENES IN ESCHERICHIA COLI K12

1980 • 103 citations

Amplification and isolation of E. coli nusA protein and studies of its effects on in vitro RNA chain elongation

1984 • 93 citations

Ligand-induced stimulation of epidermal growth factor receptor mutants with altered transmembrane regions.

1988 • 81 citations

Two different protein kinase activities are associated with the insulin receptor

1983 • 77 citations

Characterization of affinity-purified insulin receptor/kinase. Effects of dithiothreitol on receptor/kinase function.

1986 • 76 citations

Insulin-dependent intermolecular subunit communication between isolated alpha beta heterodimeric insulin receptor complexes.

1987 • 57 citations

Sites of methyl esterification on the aspartate receptor involved in bacterial chemotaxis.

1983 • 55 citations

Nucleotidylation, not phosphorylation, is the major source of the phosphotyrosine detected in enteric bacteria

1989 • 50 citations

Insulin stimulates a novel Mn2+-dependent cytosolic serine kinase in rat adipocytes.

1987 • 44 citations

Solubilization of a vectorial transmembrane receptor in functional form: aspartate receptor of chemotaxis.

1985 • 43 citations

Insulin stimulation of the insulin receptor kinase can occur in the complete absence of beta subunit autophosphorylation.

1987 • 40 citations

Substrate specificity and kinetic mechanism of human placental insulin receptor/kinase

1987 • 31 citations

Linking functional domains of the human insulin receptor with the bacterial aspartate receptor.

1986 • 25 citations