Plasmid vectors for high-efficiency expression controlled by the promoter of coliphage lambda

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Experiments in molecular genetics

1972 • 28,260 citations

Methods in Enzymology , Vol

1966 • 26,261 citations

A new method for sequencing DNA.

1977 • 7,941 citations

Construction and characterization of new cloning vehicles. II. A multipurpose cloning system. 1977.

1992 • 4,683 citations

Construction and characterization of new cloning vehicle. II. A multipurpose cloning system

1977 • 3,829 citations

Novel Method for Detection of β-Lactamases by Using a Chromogenic Cephalosporin Substrate

1972 • 1,857 citations

Complete Nucleotide Sequence of the Escherichia coli Plasmid pBR322

1979 • 1,807 citations

Nucleotide sequence of the ampicillin resistance gene of Escherichia coli plasmid pBR322.

1978 • 791 citations

Transformation of Salmonella typhimurium by Plasmid Deoxyribonucleic Acid

1974 • 777 citations

Plasmid ColE1 as a Molecular Vehicle for Cloning and Amplification of DNA

1974 • 541 citations

[17] Plasmid cloning vehicles derived from plasmids ColE1, F, R6K, and RK2

1979 • 508 citations

Construction of plasmids carrying the cI gene of bacteriophage lambda.

1976 • 410 citations

Autoregulation and Function of a Repressor in Bacteriophage Lambda

1976 • 381 citations

A Comprehensive Molecular Map of Bacteriophage LAMBDA

1979 • 277 citations

Transient rates of synthesis of individual polypeptides in E. coli following temperature shifts

1978 • 257 citations

Transformation in Escherichia coli: cryogenic preservation of competent cells

1977 • 242 citations

Nucleotide sequence of small ColE1 derivatives: Structure of the regions essential for autonomous replication and colicin E1 immunity

1979 • 226 citations

Construction of plasmid cloning vehicles that promote gene expression from the bacteriophage lambda promoter

1979 • 220 citations

Recognition sequences of repressor and polymerase in the operators of bacteriophage lambda

1975 • 211 citations

Coliphage λnutL−: A unique class of mutants defective in the site of gene N product utilization for antitermination of leftward transcription

1978 • 207 citations

Expression of human fibroblast interferon gene in Escherichia coli

1980 • 190 citations

Extracellular nucleases of Pseudomonas BAL 31. I. Characterization of single strand-specific deoxyriboendonuclease and double-strand deoxyriboexonuclease activities

1975 • 190 citations

[107] Enzymes involved in the biosynthesis of tryptophan

1962 • 187 citations

A general method for maximizing the expression of a cloned gene.

1979 • 173 citations

Studies of heat-inducible lambda bacteriophage

1966 • 167 citations

Nucleotide sequences of trpA of Salmonella typhimurium and Escherichia coli: an evolutionary comparison.

1979 • 148 citations

Cloning of cDNA of major antigen of foot and mouth disease virus and expression in E. coli

1981 • 128 citations

Two restriction endonucleases from Bacillus globiggi

1976 • 119 citations

The region between the operator and first structural gene of the tryptophan operon of Escherichia coli may have a regulatory function

1973 • 114 citations

The kil gene of bacteriophage lambda

1975 • 114 citations

Cro regulatory protein specified by bacteriophage lambda. Structure, DNA-binding, and repression of RNA synthesis.

1977 • 111 citations

Mitomycin C-induced expression of trpA of Salmonella typhimurium inserted into the plasmid ColE1

1977 • 101 citations

Location of the phage λ gene responsible for turning off λ-exonuclease synthesis

1970 • 97 citations

Isolation and characterization of deletions in bacteriophage λ residing as prophage in E. coli K12

1972 • 97 citations

Plasmid vectors containing the tryptophan operon promoter suitable for efficient regulated expression of foreign genes

1980 • 88 citations

The N protein of bacteriophage lambda, defined by its DNA sequence, is highly basic

1979 • 73 citations

Separation and analysis of promoter sites in bacteriophage lambda DNA by specific endonucleases

1974 • 64 citations

The construction and characterisation of plasmid vectors suitable for the expression of all DNA phases under the control of the E. coli tryptophan promoter

1980 • 62 citations

Construction and characterization of a plasmid containing a nearly full-size DNA copy of bacteriophage MS2 RNA

1979 • 49 citations

Use of the T4 Polynucleotide Ligase in The Joining of Flush‐Ended DNA Segments Generated by Restriction Endonucleases

1978 • 46 citations

Sequence of the promoter -operator proximal region of the major leftward RNA of bacteriophage lambda

1975 • 43 citations

Lambda phage promoter used to enhance expression of a plasmid-cloned gene

1978 • 37 citations

Control of lambda messenger RNA by the CI-immunity region

1965 • 34 citations

Quantitative aspects of gene expression in a λ-trp fusion operon

1974 • 20 citations

Stimulation of tof function and pl-proximal transcription by the N gene product of coliphage lambda

1979 • 14 citations