The angiogenic factor platelet-derived endothelial cell growth factor/thymidine phosphorylase is up-regulated in breast cancer epithelium and endothelium

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Nonparametric Estimation from Incomplete Observations

1958 • 37,219 citations

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

1992 • 4,631 citations

Angiogenesis, assessed by platelet/endothelial cell adhesion molecule antibodies, as indicator of node metastases and survival in breast cancer

1992 • 822 citations

Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial cell growth factor

1989 • 726 citations

Tumor interactions with the vasculature: angiogenesis and tumor metastasis

1990 • 598 citations

Quantitation and prognostic value of breast cancer angiogenesis: Comparison of microvessel density, Chalkley count, and computer image analysis

1995 • 450 citations

JC70: a new monoclonal antibody that detects vascular endothelium associated antigen on routinely processed tissue sections.

1990 • 428 citations

Thymidine phosphorylase is angiogenic and promotes tumor growth.

1995 • 394 citations

Relationship of endothelial cell proliferation to tumor vascularity in human breast cancer.

1993 • 209 citations

Cytokines induce thymidine phosphorylase expression in tumor cells and make them more susceptible to 5?-deoxy-5-fluorouridine

1993 • 209 citations

Expression of platelet-derived endothelial cell growth factor in Escherichia coli and confirmation of its thymidine phosphorylase activity

1992 • 209 citations

Platelet-derived endothelial cell growth factor has thymidine phosphorylase activity

1992 • 198 citations

Platelet‐derived endothelial cell growth factor/thymidine phosphorylase expression in normal tissues: An immunohistochemical study

1995 • 192 citations

Purification and tissue distribution of human thymidine phosphorylase; high expression in lymphocytes, reticulocytes and tumors

1990 • 180 citations

Novel growth regulatory factors and tumour angiogenesis

1991 • 162 citations

The angiogenic factor platelet-derived endothelial cell growth factor/thymidine phosphorylase is up-regulated in breast cancer epithelium and endothelium

1996 • 156 citations

Secretion of epidermal growth factor by macrophages associated with breast carcinoma

1993 • 150 citations

Thymidine Phosphorylase Activity Associated with Platelet-Derived Endothelial Cell Growth Factor1

1993 • 144 citations

Association of ovarian Malignancy With Expression of Paltelet-Derived Endothelial Cell Growth Factor

1994 • 139 citations

Deoxyribosyl Transfer

1964 • 139 citations

Increased sensitivity to the prodrug 5'-deoxy-5-fluorouridine and modulation of 5-fluoro-2'-deoxyuridine sensitivity in MCF-7 cells transfected with thymidine phosphorylase

1995 • 130 citations

Identification and Comparative Analysis of Thymidine Phosphorylase in the Plasma of Healthy Subjects and Cancer Patients: Brief Communication 2

1977 • 81 citations

Thymidine phosphorylase activity of platelet‐derived endothelial cell growth factor is responsible for endothelial cell mitogenicity

1993 • 76 citations

Production of platelet-derived endothelial cell growth factor by normal and transformed human cells in culture.

1989 • 60 citations

Human platelet‐derived endothelial cell growth factor is homologous to Escherichia coli thymidine phosphorylase

1992 • 44 citations

Relationship of membrane-bound tissue type and urokinase type plasminogen activators in human breast cancers to estrogen and epidermal growth factor receptors.

1988 • 34 citations

Differential expression of platelet-derived endothelial cell growth factor/thymidine phosphorylase in human lung carcinoma cell lines

1993 • 30 citations

Elevated Thymidine Phosphorylase Activity in the Plasma and Ascitic Fluids of Tumor-Bearing Animals

1978 • 28 citations

Angiogenic potency of nucleotide metabolites: Potential role in ischemia-induced vascular growth

1989 • 25 citations

Substrate specificity of a thymidine phosphorylase in human liver tumor.

1984 • 21 citations

Thymidine kinase and thymidine phosphorylase activities in various types of leukaemia and lymphoma.

1984 • 19 citations

Platelet-derived Endothelial Cell Growth Factor: Structure and function.

1991 • 19 citations

Induction of thymidine kinase activity and clonal growth of certain leukemic cell lines by a granulocyte-derived factor

1990 • 14 citations

Differential expression of platelet-derived endothelial cell growth factor/thymidine phosphorylase in human lung carcinoma cell lines

1994 • 4 citations