TGF beta in murine morphogenetic processes: the early embryo and cardiogenesis

Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro.

1986 • 2,878 citations

Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix.

1986 • 2,499 citations

Transforming growth factor beta

2011 • 1,990 citations

Detection of mRNAs in sea urchin embryos by in situ hybridization using asymmetric RNA probes

1984 • 1,638 citations

Transforming Growth Factor-β: Biological Function and Chemical Structure

1986 • 1,198 citations

Tenascin: an extracellular matrix protein involved in tissue interactions during fetal development and oncogenesis

1986 • 989 citations

Expression and secretion of type beta transforming growth factor by activated human macrophages.

1987 • 981 citations

Inhibition of endothelial cell movement by pericytes and smooth muscle cells: activation of a latent transforming growth factor-beta 1-like molecule by plasmin during co-culture.

1989 • 914 citations

Synergistic induction of mesoderm by FGF and TGF-β and the identification of an mRNA coding for FGF in the early xenopus embryo

1987 • 883 citations

Peptide growth factors are multifunctional

1988 • 835 citations

Transforming growth factor beta is an important immunomodulatory protein for human B lymphocytes.

1986 • 777 citations

Role of transforming growth factor-beta in the development of the mouse embryo.

1987 • 760 citations

Developmental Expression of PDGF, TGF-α, and TGF-β Genes in Preimplantation Mouse Embryos

1988 • 688 citations

Vasculogenesis and angiogenesis in embryonic-stem-cell-derived embryoid bodies

1988 • 667 citations

Tenascin interferes with fibronectin action

1988 • 602 citations

Expression of the proto-oncogene int-1 is restricted to specific neural cells in the developing mouse embryo

1987 • 578 citations

Phenotypic modulation of endothelial cells by transforming growth factor-beta depends upon the composition and organization of the extracellular matrix.

1988 • 571 citations

Cell adhesion protein receptors as targets for transforming growth factor-$beta; action

1987 • 498 citations

The murine transforming growth factor-beta precursor.

1986 • 492 citations

Relationship between vasculogenesis, angiogenesis and haemopoiesis during avian ontogeny

1989 • 460 citations

Tenascin: cDNA cloning and induction by TGF-beta.

1988 • 453 citations

Mesoderm Induction in Amphibians: the Role of TGF-β2-Like Factors

1988 • 452 citations

Expression of transforming growth factor-beta 1 in specific cells and tissues of adult and neonatal mice.

1989 • 451 citations

Inhibition of Endothelial Regeneration by Type-Beta Transforming Growth Factor from Platelets

1986 • 439 citations

Transforming growth factor beta increases mRNA for matrix proteins both in the presence and in the absence of changes in mRNA stability.

1988 • 420 citations

Two contrary functions of tenascin: Dissection of the active sites by recombinant tenascin fragments

1989 • 415 citations

Two forms of transforming growth factor-β distinguished by multipotential haematopoietic progenitor cells

1987 • 407 citations

Transforming growth factor-beta 1: histochemical localization with antibodies to different epitopes.

1989 • 378 citations

Tenascin is associated with chondrogenic and osteogenic differentiation in vivo and promotes chondrogenesis in vitro.

1987 • 367 citations

Embryonic expression pattern of TGF beta type-1 RNA suggests both paracrine and autocrine mechanisms of action

1988 • 347 citations

TGF-β inhibition of endothelial cell proliferation: Alteration of EGF binding and EGF-induced growth-regulatory (competence) gene expression

1987 • 344 citations

Identification of another member of the transforming growth factor type beta gene family.

1988 • 326 citations

Inhibition of endothelial cell proliferation by type β-transforming growth factor: Interactions with acidic and basic fibroblast growth factors

1986 • 312 citations

Vasculogenesis and angiogenesis: Two distinct morphogenetic mechanisms establish embryonic vascular pattern

1989 • 288 citations

Epithelial-mesenchymal cell transformation in the embryonic heart can be mediated, in part, by transforming growth factor β

1989 • 286 citations

Localized production of TGF-β mRNA in tumour promoter-stimulated mouse epidermis

1988 • 275 citations

Mesoderm induction and mesoderm-inducing factors in early amphibian development

1989 • 274 citations

Developmental expression of transforming growth factors alpha and beta in mouse fetus.

1988 • 272 citations

Antibodies to the N-terminal portion of cartilage-inducing factor A and transforming growth factor beta. Immunohistochemical localization and association with differentiating cells.

1986 • 271 citations

Epithelial-mesenchymal interactions in the developing kidney lead to expression of tenascin in the mesenchyme.

1987 • 271 citations

Features of embryonic induction

1988 • 271 citations

Boundaries defined by adhesion molecules during development of the cerebral cortex: the J1 /tenascin glycoprotein in the mouse somatosensory cortical barrel field

1989 • 268 citations

Tenascin during gut development: appearance in the mesenchyme, shift in molecular forms, and dependence on epithelial-mesenchymal interactions [published erratum appears in J Cell Biol 1989 Mar;108(3):following 1175]

1988 • 254 citations

Endothelial Adhesiveness for Blood Neutrophils Is Inhibited by Transforming Growth Factor-β

1988 • 224 citations

Transcriptional regulation of osteopontin production in rat osteosarcoma cells by type beta transforming growth factor.

1988 • 206 citations

Expression of transforming growth factor β2 RNA during murine embryogenesis

1989 • 202 citations

Type β transforming growth factor (TGFβ) regulation of alkaline phosphatase expression and other phenotype‐related mRNAs in osteoblastic rat osteosarcoma cells

1987 • 196 citations

Comparison of the biological actions of TGF beta‐1 and TGF beta‐2: Differential activity in endothelial cells

1988 • 195 citations

SEQUENCES OF INTEREST: Complementary Deoxyribonucleic Acid Cloning of a Novel Transforming Growth Factor-β Messenger Ribonucleic Acid from Chick Embryo Chondrocytes

1988 • 191 citations

Identification of a novel transforming growth factor-beta (TGF-beta 5) mRNA in Xenopus laevis.

1990 • 177 citations

Myocardial specificity for initiating endothelial-mesenchymal cell transition in embryonic chick heart correlates with a particulate distribution of fibronectin

1987 • 158 citations

Mouse embryonic transforming growth factors related to those isolated from tumor cells.

1982 • 151 citations

Participation of tenascin and transforming growth factor-beta in reciprocal epithelial-mesenchymal interactions of MCF7 cells and fibroblasts.

1989 • 150 citations

Induction of an epithelial-mesenchymal transition by an in vivo adheron-like complex

1989 • 144 citations

Protein extracts from early embryonic hearts initiate cardiac endothelial cytodifferentiation

1985 • 136 citations

Effect of transforming growth factor β on cell proliferation and glycosaminoglycan synthesis by rabbit growth-plate chondrocytes in culture

1988 • 96 citations

Transforming growth factor β: Possible roles in the regulation of normal and leukemic hematopoietic cell growth

1989 • 82 citations

The Role of TGFβ in Mouse Development^a

1990 • 45 citations

Maturation of the extracellular material of the semilunar heart valves in the mouse

1981 • 28 citations

Distribution of fibronectin during the morphogenesis of the truncus

1985 • 23 citations

Changes in endocardial cell morphology during development of the endocardial cushions

1989 • 22 citations

Observations on the development of the aortico-pulmonary spiral septum in the mouse.

1988 • 22 citations

A Novel Low Molecular Weight Ribonucleic Acid (RNA) Related to Transforming Growth Factor α Messenger RNA

1988 • 19 citations

Origin and migration of cushion tissue in the developing heart.

1981 • 15 citations