Selective Activation of Transcription by a Novel CCAAT Binding Factor

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis

1981 • 2,828 citations

DNAase footprinting a simple method for the detection of protein-DNA binding specificity

1978 • 2,092 citations

A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: application to components of the Escherichia coli lactose operon regulatory system

1981 • 1,991 citations

Regulation of Inducible and Tissue-Specific Gene Expression

1987 • 1,640 citations

Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins

1985 • 1,248 citations

Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region

1985 • 1,244 citations

A cellular DNA-binding protein that activates eukaryotic transcription and DNA replication

1987 • 1,050 citations

Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of Yeast

1986 • 946 citations

Deletion analysis of GAL4 defines two transcriptional activating segments

1987 • 898 citations

A multiplicity of CCAAT box-binding proteins

1987 • 745 citations

Human CCAAT-binding proteins have heterologous subunits

1988 • 712 citations

Separation of DNA Binding from the Transcription-Activating Function of a Eukaryotic Regulatory Protein

1986 • 626 citations

Genetic Switch

2008 • 590 citations

Homologous recognition of a promoter domain common to the MSV LTR and the HSV tk gene

1986 • 562 citations

Fine Structure Genetic Analysis of a β-Globin Promoter

1986 • 479 citations

Synthesis of double-stranded DNA complementary to lysozyme, ovomucoid, and ovalbumin mRNAs. Optimization for full length second strand synthesis by Escherichia coli DNA polymerase I.

1978 • 395 citations

A yeast and a human CCAAT-binding protein have heterologous subunits that are functionally interchangeable

1988 • 263 citations

Insertion of retrovirus into the first intron of alpha 1(I) collagen gene to embryonic lethal mutation in mice.

1984 • 229 citations

DNA sequence required for initiation of transcription in vitro from the major late promoter of adenovirus 2.

1981 • 216 citations

A CCAAT DNA binding factor consisting of two different components that are both required for DNA binding.

1988 • 175 citations

Identification of a cell-specific transcriptional enhancer in the first intron of the mouse alpha 2 (type I) collagen gene.

1987 • 169 citations

Interactions between a DNA-binding transcription factor (COUP) and a non-DNA binding factor (S300-II)

1987 • 158 citations

Separate binding sites for nuclear factor 1 and a CCAAT DNA binding factor in the mouse alpha 2(I) collagen promoter.

1987 • 109 citations

Point mutations and small substitution mutations in three different upstream elements inhibit the activity of the mouse alpha 2(I) collagen promoter.

1988 • 84 citations

Partial purification of a nuclear protein that binds to the CCAAT box of the mouse alpha 1-globin gene.

1986 • 83 citations

Differential binding of a CCAAT DNA binding factor to the promoters of the mouse alpha 2(I) and alpha 1(III) collagen genes.

1986 • 72 citations

Purification and characterization of chicken ovalbumin gene upstream promoter transcription factor from homologous oviduct cells.

1987 • 42 citations