Separation of DNA Binding from the Transcription-Activating Function of a Eukaryotic Regulatory Protein

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes.

1985 • 2,450 citations

Yeast transformation: a model system for the study of recombination.

1981 • 1,491 citations

Sequences That Regulate the Divergent GAL1-GAL10 Promoter in Saccharomyces cerevisiae

1984 • 955 citations

Vectors bearing a hybrid trp-lac promoter useful for regulated expression of cloned genes in Escherichia coli

1983 • 810 citations

lac repressor-operator interaction

1970 • 791 citations

Specific DNA binding of GAL4, a positive regulatory protein of yeast

1985 • 767 citations

The Molecular Biology of the Yeast Saccharomyces (Metabolism and Gene Expression)

1985 • 712 citations

A eukaryotic transcriptional activator bearing the DNA specificity of a prokaryotic repressor

1985 • 686 citations

Genetic Switch

2008 • 590 citations

A GAL10-CYC1 hybrid yeast promoter identifies the GAL4 regulatory region as an upstream site.

1982 • 575 citations

Enhancers and eukaryotic gene transcription

1985 • 515 citations

GCN4 protein, synthesize in vitro, binds HIS3 regulatory sequences: Implications for general control of amino acid biosynthetic genes in yeast

1985 • 496 citations

Negatively supercoiled simian virus 40 DNA contains Z-DNA segments within transcriptional enhancer sequences

1983 • 474 citations

How the λ repressor and cro work

1980 • 452 citations

Cooperative binding of λ repressors to sites separated by integral turns of the DNA helix

1986 • 450 citations

Homology among DNA-binding proteins suggests use of a conserved super-secondary structure

1982 • 432 citations

Saccharomyces cerevisiae GAL1-GAL10 Divergent Promoter Region: Location and Function of the Upstream Activating Sequence UAS_G

1984 • 395 citations

Domain structure of human glucocorticoid receptor and its relationship to the v-erb-A oncogene product

1985 • 368 citations

The organization and transcription of the galactose gene cluster of Saccharomyces

1981 • 350 citations

Interactions between DNA-bound repressors govern regulation by the λ phage repressor

1979 • 329 citations

Repressor structure and the mechanism of positive control

1983 • 324 citations

Use of lacZ fusions to delimit regulatory elements of the inducible divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae.

1984 • 310 citations

Amino terminus of the yeast GAL4 gene product is sufficient for nuclear localization.

1984 • 284 citations

Primary Structure of the Saccharomyces cerevisiae GAL4 Gene

1984 • 276 citations

Specific protein binding to far upstream activating sequences in polymerase II promoters.

1985 • 246 citations

Gene regulation at the right operator (OR) of bacteriophage λ

1980 • 241 citations

A bacterial repressor protein or a yeast transcriptional terminator can block upstream activation of a yeast gene

1984 • 237 citations

Binding of a simian virus 40 T antigen-related protein to DNA

1981 • 233 citations

Yeast promoters: Positive and negative elements

1984 • 227 citations

Two Decades of Research on Biosynthesis of Saccharides

1971 • 191 citations

Changing the binding specificity of a represser by redesigning an α-helix

1985 • 176 citations

[76] Bacteriophage λ repressor and cro protein: Interactions with operator DNA

1980 • 154 citations

A synthetic HIS4 regulatory element confers general amino acid control on the cytochrome c gene (CYC1) of yeast.

1985 • 144 citations

A phage repressor–operator complex at 7 Å resolution

1985 • 140 citations

Multiple binding sites for polyomavirus large T antigen within regulatory sequences of polyomavirus DNA

1984 • 121 citations

The and 434 Phage Repressors

1970 • 116 citations

Regulation of the galactose pathway in Saccharomyces cerevisiae : Induction of uridyl transferase mRNA and dependency on GAL4 gene function

1978 • 114 citations

Gene regulation at the right operator (OR) of bacteriophage λ

1980 • 108 citations

Nucleotide sequence of the ARGRII regulatory gene and amino acid sequence homologies between ARGRII PPRI and GAL4 regulatory proteins

1986 • 100 citations

Mutant lambda phage repressor with a specific defect in its positive control function.

1982 • 93 citations

Molecular expression and regulation of the galactose pathway genes in Saccharomyces cerevisiae. Distinct messenger RNAs specified by the Gali and Gal7 genes in the Gal7-Gal10-Gal1 cluster.

1978 • 41 citations

Transcription of the human β-globin gene is stimulated by an SV40 enhancer to which it is physically linked but topologically uncoupled

1986 • 36 citations