Polymorphisms in the 3′-untranslated region of human and monkey dopamine transporter genes affect reporter gene expression

Association of attention-deficit disorder and the dopamine transporter gene.

1995 • 1,023 citations

Human dopamine transporter gene (DAT1) maps to chromosome 5p15.3 and displays a VNTR

1992 • 718 citations

Striatal dopamine nerve terminal markers in human, chronic methamphetamine users

1996 • 715 citations

The human serotonin transporter gene linked polymorphism (5-HTTLPR) shows ten novel allelic variants

2000 • 622 citations

Cloning and Expression of a Cocaine-Sensitive Rat Dopamine Transporter

1991 • 587 citations

Cloning and Expression of a Cocaine-Sensitive Dopamine Transporter Complementary DNA

1991 • 584 citations

Molecular characterization of the dopamine transporter

1993 • 560 citations

Genotype Influences In Vivo Dopamine Transporter Availability in Human Striatum

2000 • 550 citations

Increased striatal dopamine transporter in adult patients with attention deficit hyperactivity disorder: effects of methylphenidate as measured by single photon emission computed tomography

2000 • 517 citations

Confirmation of association between attention deficit hyperactivity disorder and a dopamine transporter polymorphism

1997 • 498 citations

Dopamine nerve terminal degeneration produced by high doses of methylamphetamine in the rat brain

1982 • 480 citations

Association and Linkage of the Dopamine Transporter Gene and Attention-Deficit Hyperactivity Disorder in Children: Heterogeneity owing to Diagnostic Subtype and Severity

1998 • 467 citations

Cytoplasmic regulation of mRNA function: The importance of the 3′ untranslated region

1993 • 391 citations

Mapping susceptibility loci in attention deficit hyperactivity disorder: preferential transmission of parental alleles at DAT1, DBH and DRD5 to affected children

1999 • 390 citations

Single photon emission computed tomographic imaging demonstrates loss of striatal dopamine transporters in Parkinson disease.

1993 • 363 citations

Positron emission tomographic imaging of the dopamine transporter with ¹¹C‐WIN 35,428 reveals marked declines in mild Parkinson's disease

1993 • 319 citations

Attention deficit hyperactivity disorder: binding of [99mTc]TRODAT-1 to the dopamine transporter before and after methylphenidate treatment

2000 • 285 citations

Evidence suggesting the role of specific genetic factors in cigarette smoking.

1999 • 282 citations

Prediction of Dopamine Transporter Binding Availability by Genotype: A Preliminary Report

2000 • 279 citations

Polygenic inheritance of Tourette syndrome, stuttering, attention deficit hyperactivity, conduct, and oppositional defiant disorder: The additive and subtractive effect of the three dopaminergic genes—DRD2, DβH, and DAT1

1996 • 271 citations

Association of the Dopamine Transporter Gene (DAT1) With Poor Methylphenidate Response

1999 • 256 citations

Biogenic amine transporters: regulation in flux

2000 • 245 citations

Diversity of cytoplasmic functions for the 3′ untranslated region of eukaryotic transcripts

1995 • 241 citations

Evidence suggesting the role of specific genetic factors in cigarette smoking.

1999 • 240 citations

Dopamine transporters are markedly reduced in Lesch-Nyhan disease in vivo.

1996 • 238 citations

Severe depletion of cocaine recognition sites associated with the dopamine transporter in Parkinson's‐diseased striatum

1991 • 237 citations

[123I]beta-CIT SPECT imaging of striatal dopamine transporter binding in Tourette's disorder

1995 • 226 citations

Decreased dopamine transporters with age in healthy human subjects

1994 • 205 citations

A genetic association for cigarette smoking behavior.

1999 • 203 citations

Genetic Association between Dopamine Transporter Protein Alleles and Cocaine-Induced Paranoia

1994 • 198 citations

Global variation of a 40-bp VNTR in the 3′-untranslated region of the dopamine transporter gene (SLC6A3)

1999 • 184 citations

Dopamine transporter mRNA content in human substantia nigra decreases precipitously with age.

1992 • 179 citations

Striatal dopamine transporter density in major depression

1999 • 173 citations

Comparison of the role of dopamine, serotonin, and noradrenaline genes in ADHD, ODD and conduct disorder: multivariate regression analysis of 20 genes

2000 • 164 citations

Iodine-123-beta-CIT and iodine-123-FPCIT SPECT measurement of dopamine transporters in healthy subjects and Parkinson's patients.

1998 • 156 citations

Allelic association of a dopamine transporter gene polymorphism in alcohol dependence with withdrawal seizures or delirium

1997 • 153 citations

Multivariate analysis of associations of 42 genes in ADHD, ODD and conduct disorder

2000 • 153 citations

A family-based and case-control association study of the dopamine D4 receptor gene and dopamine transporter gene in attention deficit hyperactivity disorder

2000 • 152 citations

Neurotransmitter transporters: fruitful targets for CNS drug discovery

2000 • 141 citations

Human dopamine transporter gene: coding region conservation among normal, Tourette's disorder, alcohol dependence and attention-deficit hyperactivity disorder populations

2000 • 136 citations

Distribution of the 3' VNTR polymorphism in the human dopamine transporter gene in world populations.

2000 • 119 citations

Rapid detection of Parkinson's disease by SPECT with altropane: A selective ligand for dopamine transporters

1998 • 117 citations

Cloning of dopamine, norepinephrine and serotonin transporters from monkey brain: relevance to cocaine sensitivity

2001 • 109 citations

Association of smoking and personality with a polymorphism of the dopamine transporter gene: Results from a community survey

2000 • 109 citations

Systematic screening for DNA sequence variation in the coding region of the human dopamine transporter gene (DAT1)

2000 • 107 citations

Association of a polymorphism in the dopamine‐transporter gene with parkinson's disease

1997 • 96 citations

Identification of a novel polymorphism of the human dopamine transporter (DAT1) gene and the significant association with alcoholism

1999 • 92 citations

Modification of Alcohol Withdrawal by the A₉Allele of the Dopamine Transporter Gene

1998 • 91 citations

Population genetic study of the human dopamine transporter gene (DAT1)

1995 • 87 citations

The Neurobiology of Cocaine: Cellular and Molecular Mechanisms

1995 • 75 citations

Technepine: A high-affinity99mtechnetium probe to label the dopamine transporter in brain by SPECT imaging

1996 • 67 citations

Dopamine transporter gene polymorphisms are not associated with polysubstance abuse

1993 • 62 citations

Genotypic association between dopamine transporter gene polymorphisms and schizophrenia

1997 • 60 citations

Altropane, a SPECT or PET imaging probe for dopamine neurons: III. Human dopamine transporter in postmortem normal and Parkinson's diseased brain

1998 • 55 citations

A rapid and reversible change in dopamine transporters induced by methamphetamine

1997 • 55 citations

DAT1 gene polymorphism in alcoholism: a family-based association study

1999 • 54 citations

Polymorphisms of dopamine receptor and transporter genes and Parkinson's disease

1995 • 47 citations

Single nucleotide polymorphisms distinguish multiple dopamine transporter alleles in primates: implications for association with attention deficit hyperactivity disorder and other neuropsychiatric disorders

2000 • 45 citations

The human dopamine transporter gene: the 5′-flanking region reveals five diallelic polymorphic sites in a Caucasian population sample

2001 • 43 citations

The 3′ UTR of Human MnSOD mRNA Hybridizes to a Small Cytoplasmic RNA and Inhibits Gene Expression

2000 • 41 citations

Variable number tandem repeat dopamine transporter gene polymorphism and Parkinson's disease: no association found

1999 • 38 citations

Human dopamine transporter gene polymorphism (VNTR) and alcoholism

1997 • 38 citations

Dopamine transporter gene polymorphism and psychiatric symptoms seen in schizophrenic patients at their first episode

1996 • 38 citations

A single nucleotide polymorphism of dopamine transporter gene is associated with Parkinson's disease

2000 • 34 citations

Efficiency of different viral promoters in directing gene expression in mammalian cells: Effect of 3′-untranslated sequences

1996 • 25 citations

Human phosducin-like protein (hPhLP) messenger RNA stability is regulated by cis-acting instability elements present in the 3′-untranslated region

1999 • 23 citations

The Parvovirus H-1 NS2 Protein Affects Viral Gene Expression through Sequences in the 3′ Untranslated Region

1993 • 19 citations

Lack of association between dopamine transporter gene polymorphisms and delusional disorder.

1998 • 19 citations

Genetic Variation in the 3′ Untranslated Region of the Neurofibromatosis 1 Gene: Application to Unequal Allelic Expression

1998 • 17 citations

Lack of association between dopamine transporter gene polymorphisms and delusional disorder

1998 • 16 citations

Plasma homovanillic acid and the dopamine transporter during cocaine withdrawal

1998 • 13 citations

Translational regulation of parathyroid hormone gene expression and RNA: Protein interactions

1996 • 10 citations

Tenotomy decreases reporter protein synthesis via the 3′-untranslated region of the β-myosin heavy chain mRNA

2000 • 10 citations

Site-directed mutagenesis of the -10 region of the lacUV5 promoter. Introduction of dA4.dT4 tract suppresses open complex formation.

1990 • 6 citations