Biogenic amine transporters: regulation in flux

Association of Anxiety-Related Traits with a Polymorphism in the Serotonin Transporter Gene Regulatory Region

1996 • 5,154 citations

Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter

1996 • 2,452 citations

Characterization of single-nucleotide polymorphisms in coding regions of human genes

1999 • 1,531 citations

A New ER Trafficking Signal Regulates the Subunit Stoichiometry of Plasma Membrane KATP Channels

1999 • 1,038 citations

Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis

1999 • 1,023 citations

Association of attention-deficit disorder and the dopamine transporter gene.

1995 • 1,023 citations

Expression cloning of a cocaine-and antidepressant-sensitive human noradrenaline transporter

1991 • 928 citations

Role of Serotonin in the Paradoxical Calming Effect of Psychostimulants on Hyperactivity

1999 • 873 citations

Cloning and Expression of a Rat Brain GABA Transporter

1990 • 873 citations

Altered Brain Serotonin Homeostasis and Locomotor Insensitivity to 3,4-Methylenedioxymethamphetamine (“Ecstasy”) in Serotonin Transporter-Deficient Mice

1998 • 704 citations

Profound neuronal plasticity in response to inactivation of the dopamine transporter

1998 • 702 citations

Orthostatic Intolerance and Tachycardia Associated with Norepinephrine-Transporter Deficiency

2000 • 595 citations

The dopamine transporter is localized to dendritic and axonal plasma membranes of nigrostriatal dopaminergic neurons

1996 • 473 citations

Mice lacking the norepinephrine transporter are supersensitive to psychostimulants

2000 • 458 citations

Evidence of linkage between the serotonin transporter and autistic disorder

1997 • 435 citations

Mapping susceptibility loci in attention deficit hyperactivity disorder: preferential transmission of parental alleles at DAT1, DBH and DRD5 to affected children

1999 • 390 citations

Cocaine, Ethanol, and Genotype Effects on Human Midbrain Serotonin Transporter Binding Sites and mRNA Levels

1998 • 390 citations

Phosphorylation and Sequestration of Serotonin Transporters Differentially Modulated by Psychostimulants

1999 • 387 citations

Membrane Trafficking Regulates the Activity of the Human Dopamine Transporter

1999 • 378 citations

Protein Kinase C Activation Regulates Human Serotonin Transporters in HEK-293 Cells via Altered Cell Surface Expression

1997 • 377 citations

Regulated Trafficking of the Human Dopamine Transporter

1999 • 357 citations

Effects of Chronic Antidepressant Treatments on Serotonin Transporter Function, Density, and mRNA Level

1999 • 336 citations

Phosphorylation and Regulation of Antidepressant-sensitive Serotonin Transporters

1998 • 312 citations

Protein Kinase C-mediated Phosphorylation and Functional Regulation of Dopamine Transporters in Striatal Synaptosomes

1997 • 298 citations

Localization and Dynamic Regulation of Biogenic Amine Transporters in the Mammalian Central Nervous System

1998 • 276 citations

Immunolocalization of the cocaine- and antidepressant-sensitive l-norepinephrine transporter

2000 • 273 citations

Serotonin transporter (5-HTT) gene variants associated with autism?

1997 • 260 citations

Neurotransmitter transporters : structure, function, and regulation

2002 • 251 citations

Dopamine D₂ Receptor‐Deficient Mice Exhibit Decreased Dopamine Transporter Function but No Changes in Dopamine Release in Dorsal Striatum

1999 • 233 citations

Protein kinase C modulates the activity of a cloned gamma-aminobutyric acid transporter expressed in Xenopus oocytes via regulated subcellular redistribution of the transporter.

1994 • 211 citations

Phorbol Esters Increase Dopamine Transporter Phosphorylation and Decrease Transport V_max

1997 • 187 citations

Regulated phosphorylation and trafficking of antidepressant-sensitive serotonin transporter proteins

1998 • 187 citations

Activation of protein kinase C inhibits uptake, currents and binding associated with the human dopamine transporter expressed in Xenopus oocytes.

1997 • 186 citations

Protein kinase-mediated bidirectional trafficking and functional regulation of the human dopamine transporter

1998 • 173 citations

Regulation of γ-Aminobutyric Acid (GABA) Transporters by Extracellular GABA

1999 • 164 citations

Acute regulation of norepinephrine transport: II. PKC-modulated surface expression of human norepinephrine transporter proteins.

1998 • 157 citations

PDZ-mediated interactions retain the epithelial GABA transporter on the basolateral surface of polarized epithelial cells

1999 • 155 citations

Protein kinase C inhibitors block amphetamine-mediated dopamine release in rat striatal slices.

1998 • 151 citations

Acute regulation of norepinephrine transport: I. protein kinase C-linked muscarinic receptors influence transport capacity and transporter density in SK-N-SH cells.

1998 • 148 citations

Second Messengers, Trafficking-Related Proteins, and Amino Acid Residues that Contribute to the Functional Regulation of the Rat Brain GABA Transporter GAT1

1997 • 140 citations

Protein Kinase C Regulates the Interaction between a GABA Transporter and Syntaxin 1A

1998 • 136 citations

Multiple G Protein-Coupled Receptors Initiate Protein Kinase C Redistribution of GABA Transporters in Hippocampal Neurons

1999 • 101 citations

Polarized Expression of the Antidepressant-Sensitive Serotonin Transporter in Epinephrine-Synthesizing Chromaffin Cells of the Rat Adrenal Gland

1997 • 100 citations

Differential polarization of serotonin transporters in axons versus soma–dendrites: an immunogold electron microscopy study

1999 • 89 citations

Neurotransmitter Transporters: Regulators of Function and Functional Regulation

1998 • 86 citations

Down‐Regulation of the Human Norepinephrine Transporter in Intact 293‐hNET Cells Exposed to Desipramine

1998 • 84 citations

The human noradrenaline transporter gene contains multiple polyadenylation sites and two alternatively spliced C-terminal exons

1998 • 66 citations

Possible Existence of Quaternary Structure in the High-Affinity Serotonin Transport Complex

1998 • 65 citations

The Structure and Function of Norepinephrine, Dopamine, and Serotonin Transporters

1997 • 64 citations

Dominant Negative Isoform of Rat Norepinephrine Transporter Produced by Alternative RNA Splicing

1999 • 55 citations

Injection of the protein kinase C inhibitor Ro31-8220 into the nucleus accumbens attenuates the acute response to amphetamine: tissue and behavioral studies

1998 • 54 citations

Serotonin transporter candidate gene studies in affective disorders and personality: promises and potential pitfalls

1998 • 50 citations

Oligomerization of serotonin transporter and its functional consequences

2000 • 43 citations

5-HT1B antagonists modulate clearance of extracellular serotonin in rat hippocampus

1999 • 40 citations

Expression and regulation of the human dopamine transporter in a neuronal cell line

1998 • 36 citations

Arachidonic Acid Stimulates a Novel Cocaine-Sensitive Cation Conductance Associated with the Human Dopamine Transporter

2000 • 34 citations

Differential regulation of mammalian brain‐specific proline transporter by calcium and calcium‐dependent protein kinases

2000 • 14 citations